Preprints (not yet peer-reviewed)

17 downloads
88 views

In recent years, the pharmaceutical industry has been confronted with rising R&D costs paired with decreasing productivity. Attrition rates for new molecules are tremendous, with a substantial number of molecules failing in an advanced stage of development. Repositioning...

["Bioinformatics","Drugs and Devices","Computational Science","Data Mining and Machine Learning","Data Science"]
doi:10.7287/peerj.preprints.27002v1
641 downloads
894 views

Random forest and similar Machine Learning techniques are already used to generate spatial predictions, but spatial location of points (geography) is often ignored in the modeling process. Spatial auto-correlation, especially if still existent in the cross-validation...

["Biogeography","Soil Science","Computational Science","Data Mining and Machine Learning","Spatial and Geographic Information Science"]
doi:10.7287/peerj.preprints.26693v2
100 downloads
255 views

The material-weight illusion (MWI) is one example in a class of weight perception illusions that seem to defy principled explanation. In this illusion, when an observer lifts two objects of the same size and mass, but that appear to be made of different materials,...

["Neuroscience","Psychiatry and Psychology","Computational Science"]
doi:10.7287/peerj.preprints.26825v1
138 downloads
291 views

Identifying and counting individual fish on videos is a crucial task to cost-effectively monitor marine biodiversity, but it remains a difficult and time-consuming task. In this paper, we present a method to assist the automated identification of fish species on...

["Biodiversity","Computational Science","Data Science"]
doi:10.7287/peerj.preprints.26818v1
86 downloads
199 views

Protein-Protein interaction plays an important role in the life processes. Molecular mechanisms of the related processes can be better understood with the help of interface prediction. In this work, we use game theory concept of Shapley value to analyse the spatial...

["Bioinformatics","Computational Science"]
doi:10.7287/peerj.preprints.26785v1
54 downloads
160 views

Time-resolved phylogenetic methods use information about the time of sample collection to estimate the rate of evolution. Originally, the models used to estimate evolutionary rates were quite simple, assuming that all lineages evolve at the same rate, an assumption...

["Bioinformatics","Genetics","Computational Science"]
doi:10.7287/peerj.preprints.26744v1
2,281 downloads
4,480 views

Computers are a central tool in the research process, enabling complex and large scale data analysis. As computer-based research has increased in complexity, so have the challenges of ensuring that this research is reproducible. To address this challenge, we review...

["Anthropology","Computational Biology","Science and Medical Education","Computational Science","Data Science"]
doi:10.7287/peerj.preprints.3192v2
75 downloads
256 views

The ability of vertebrates to generate rhythm within their spinal neural networks is essential for walking, running, and other rhythmic behaviors. The central pattern generator (CPG) network responsible for these behaviors is well-characterized with experimental...

["Animal Behavior","Bioinformatics","Computational Biology","Neuroscience","Computational Science"]
doi:10.7287/peerj.preprints.26734v1
182 downloads
146 views

The classification of fresh fruits according to their ripeness is typically a subjective and tedious task; consequently, there is growing interest in the use of non-contact techniques such as those based on computer vision and machine learning. In this paper, we...

["Agricultural Science","Computational Biology","Food Science and Technology","Computational Science","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.26691v1
232 downloads
545 views

Emotion expression encompasses various types of information, including face and eye movement, voice and body motion. Most of the studies in automated affective recognition use faces as stimuli, less often they include speech and even more rarely gestures. Emotions...

["Neuroscience","Human-Computer Interaction","Computational Science","Data Mining and Machine Learning","Data Science"]
doi:10.7287/peerj.preprints.26688v1
118 downloads
222 views

When the task is reading nonwords aloud, skilled adult readers are very variable in the responses they produce: a nonword can evoke as many as 24 different responses in a group of such readers. Why is nonword reading so variable? We analysed a large database of...

["Cognitive Disorders","Psychiatry and Psychology","Computational Science"]
doi:10.7287/peerj.preprints.26647v1
319 downloads
691 views

The demand for reproducibility of research is on the rise in disciplines concerned with data analysis and computational methods. In this work existing recommendations for reproducible research are reviewed and translated into criteria for assessing reproducibility...

["Science Policy","Computational Science","Data Science","Spatial and Geographic Information Science"]
doi:10.7287/peerj.preprints.26561v1
200 downloads
336 views

Dot plots are widely used to quickly compare sequence sets. They provide a synthetic similarity overview, highlighting repetitions, breaks and inversions. Different tools have been developed to easily generated genomic alignment dot plots, but they are often limited...

["Bioinformatics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.26567v1
70 downloads
229 views

Proteins that modify the activity of transcription factor (TF), often called modulators, play a vital role in gene transcriptional regulation. Alternative splicing is a critical step of gene processing and it can modulate gene function by adding or removing certain...

["Bioengineering","Bioinformatics","Biotechnology","Genetics","Computational Science"]
doi:10.7287/peerj.preprints.26482v1
24,853 downloads
65,973 views

The website Sci-Hub enables users to download PDF versions of scholarly articles, including many articles that are paywalled at their journal’s site. Sci-Hub has grown rapidly since its creation in 2011, but the extent of its coverage was unclear. Here we report...

["Bioinformatics","Legal Issues","Science and Medical Education","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.3100v3
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