Preprints (not yet peer-reviewed)

30 downloads
43 views

Causality testing methods are being widely used in various disciplines of science. Model-free methods for causality estimation are very useful as the underlying model generating the data is often unknown. However, existing model-free measures assume separability...

["Adaptive and Self-Organizing Systems","Data Science","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.27416v1
16 downloads
42 views

The problem of aircraft conflict avoidance for Air Traffic Management systems is studied. In the scenario, aircraft are considered to fly within a shared three-dimensional airspace and not allowed to approach close less than a minimum safe separation during their...

["Optimization Theory and Computation","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.27410v1
57 downloads
96 views

The concept underlying precision medicine is that prevention, diagnosis and treatment of pathologies such as cancer can be improved through an understanding of the influence of individual patient characteristics. Predictive medicine seeks to derive this understanding...

["Computational Biology","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.27299v1
122 downloads
153 views

Building more open-ended evolutionary systems can simultaneously advance our understanding of biology, artificial life, and evolutionary computation. In order to do so, however, we need a way to determine when we are moving closer to this goal. We propose a set...

["Computational Biology","Adaptive and Self-Organizing Systems","Agents and Multi-Agent Systems","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.27249v3
30 downloads
48 views

Open source projects may face a forking situation at some point during their life-cycle. The traditional view is that forks are a waste of project resources and should be avoided. However, in a wider technological and organisational context, forks can be a way...

["Scientific Computing and Simulation","Software Engineering"]
doi:10.7287/peerj.preprints.27159v1
84 downloads
125 views

This paper addresses two questions related to reproducibility within the context of research related to computer science. First, requirements on reproducibility are analyzed based on a survey addressed to researchers in the academic and private sector. The survey...

["Data Science","Scientific Computing and Simulation","Software Engineering"]
doi:10.7287/peerj.preprints.27082v1
115 downloads
280 views

Fine-scale evolutionary dynamics can be challenging to tease out when focused on broad brush strokes of whole populations over long time spans. We propose a suite of diagnostic metrics that operate on lineages and phylogenies in digital evolution experiments with...

["Computational Biology","Adaptive and Self-Organizing Systems","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.26883v1
293 downloads
363 views

Background. Over the last few decades, in developing nations including India, there have been rapid developments in information and communication technologies with progress towards sustainable development goals facilitating universal access to education. With the...

["Emerging Technologies","Scientific Computing and Simulation","World Wide Web and Web Science","Software Engineering"]
doi:10.7287/peerj.preprints.26715v1
219 downloads
460 views

Most of today’s scientific research relies on computers and software not only for administrational tasks, but also for processing scientific information. Examples of such computer-aided research are the analysis of experimental data or the simulation of phenomena...

["Human-Computer Interaction","Digital Libraries","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.26633v1
190 downloads
288 views

Being able to quantify the similarity between two protein complexes is essential for numerous applications. Prominent examples are database searches for known complexes with a given query complex, comparison of the output of different protein complex prediction...

["Bioinformatics","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.26612v1
147 downloads
349 views

The surgical skills required to successfully maintain hemostasis, the control of operative blood, requires considerable deliberate practice. Hemostasis requires the deft orchestration of bi-dexterous tool manipulation. We present our approach to computationally...

["Human-Computer Interaction","Graphics","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.3334v2
150 downloads
245 views

Configuration files are widely used by scientists and researchers to configure the parameters and initial settings for their computer programs. We present here a Python package that adds physical quantities to these parameters and validate them against user defined...

["Scientific Computing and Simulation","Programming Languages","Software Engineering"]
doi:10.7287/peerj.preprints.3418v1
215 downloads
280 views

We present a linear time-varying Luenberger observer (LTVLO) using compartmental models to estimate the unmeasurable states in patients with type 1 diabetes. The LTVLO proposed is based on the linearization in an operation point of the virtual patient (VP), where...

["Algorithms and Analysis of Algorithms","Scientific Computing and Simulation","Theory and Formal Methods"]
doi:10.7287/peerj.preprints.3341v1
409 downloads
845 views

Landscape genetics combines population genetics, landscape ecology, and spatial analysis to identify landscape and genetic factors that influence genetic and genomic variation. Progress in the field depends on a strong conceptual foundation and the means of identifying...

["Computational Biology","Scientific Computing and Simulation","Spatial and Geographic Information Systems"]
doi:10.7287/peerj.preprints.2225v5
320 downloads
334 views

Background. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease primarily affecting upper and lower motor neurons in the brain and spinal cord. The heterogeneity in the course of ALS clinical progression and ultimately survival, coupled...

["Bioinformatics","Computational Biology","Data Mining and Machine Learning","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.3262v1
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