Preprints (not yet peer-reviewed)

103 downloads
322 views

The ability of vertebrates to generate rhythm within their spinal neural networks is essential for walking, running, and other rhythmic behaviors. The central pattern generator (CPG) network responsible for these behaviors is well-characterized with experimental...

["Animal Behavior","Bioinformatics","Computational Biology","Neuroscience","Computational Science"]
doi:10.7287/peerj.preprints.26734v2
103 downloads
397 views

The success of personalized medicine does not only rely on methodological advances but also on the availability of data to learn from. While the generation and sharing of large data sets is becoming increasingly easier, there is a remarkable lack of diversity within...

["Genomics","Neuroscience","Ethical Issues","Data Mining and Machine Learning","Data Science"]
doi:10.7287/peerj.preprints.27079v1
116 downloads
176 views

Introduction: Sleep scoring is an important step in the treatment of sleep disorders. Manual annotation of sleep stages is time-consuming and experience-relevant and, therefore, needs to be done using machine learning techniques. methods: Sleep-edf polysomnography...

["Bioinformatics","Neuroscience","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27020v1
172 downloads
410 views

Background The Human hand can perform a range of manipulation tasks, from holding a pen to holding a hammer. Central Nervous System (CNS) uses different strategies in different manipulation tasks based on task requirements. Several attempts to compare postures...

["Bioengineering","Neuroscience","Kinesiology","Computational Science"]
doi:10.7287/peerj.preprints.3080v2
80 downloads
201 views

A simulation based study on model fitting for sensory neurons from stimulus/response data is presented. The employed model is a continuous time recurrent neural network (CTRNN) which is a member of models with known universal approximation features. This feature...

["Computational Biology","Neuroscience"]
doi:10.7287/peerj.preprints.27015v1
54 downloads
201 views

Background. Human multitasking is typically defined as the practice of performing more than one task at the same time (dual-task) or rapidly alternating between multiple tasks (task switching). The majority of research in multitasking has been focusing on individual...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27010v1
61 downloads
161 views

GDF11, a member of TGF-β superfamily, has recently received widespread attention as a novel anti-ageing/rejuvenation factor to reverse age-related dysfunctions in heart and skeletal muscle, and to induce angiogenesis and neurogenesis. However, these positive effects...

["Biochemistry","Bioinformatics","Cell Biology","Neuroscience","Evidence Based Medicine"]
doi:10.7287/peerj.preprints.27003v1
38 downloads
106 views

Sudden unexpected death in epilepsy (SUDEP) is a common cause of premature death amongst epilepsy patients. It is hypothesized to result from cardiorespiratory dysfunction, but the exact aetiology is unknown. The aim of this study was to determine if functional...

["Neuroscience","Anatomy and Physiology"]
doi:10.7287/peerj.preprints.26999v1
42 downloads
165 views

Identifying the best framework for two-choice decision-making has been a goal of psychology theory for many decades (Bohil, Szalma, & Hancock, 2015; Macmillan & Creelman, 1991). There are two main candidates: the theory of signal detectability (TSD) (Swets, Tanner...

["Mathematical Biology","Neuroscience","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.26978v1
64 downloads
99 views

Microglia are highly ramified brain phagocytes that are finely tuned to surrounding neuronal and glial activity. Combined, microglia morphology, dynamic process movement, phagocytic, and neuroinflammatory responses aid in the detection of changed neuronal function,...

["Neuroscience","Neurology"]
doi:10.7287/peerj.preprints.26937v1
222 downloads
541 views

Lesion of the dopaminergic neurons of the nigrostriatal system is a key feature of Parkinson's disease (PD). Alpha-synuclein is a protein that is a major component of Lewy bodies, histopathological hallmarks of PD, and is involved in regulation of dopamine (DA)...

["Developmental Biology","Neuroscience","Neurology","Pathology"]
doi:10.7287/peerj.preprints.26547v2
536 downloads
1,526 views

Physiological mechanisms for passive and active transmembrane transport have been theoretically described using many different approaches. A generic formulation for both passive and active transmembrane transport, is derived from basic thermodynamical principles...

["Biophysics","Mathematical Biology","Neuroscience"]
doi:10.7287/peerj.preprints.1312v8
57 downloads
229 views

The variation between the actual and perceived lightness of a stimulus has strong dependency on its background, a phenomena commonly known as lightness induction in the literature of visual neuroscience and psychology. For instance, a gray patch may perceptually...

["Neuroscience"]
doi:10.7287/peerj.preprints.26831v1
125 downloads
278 views

The material-weight illusion (MWI) is one example in a class of weight perception illusions that seem to defy principled explanation. In this illusion, when an observer lifts two objects of the same size and mass, but that appear to be made of different materials,...

["Neuroscience","Psychiatry and Psychology","Computational Science"]
doi:10.7287/peerj.preprints.26825v1
39 downloads
137 views

Many experiments have demonstrated that the rhythms in the brain influence an initial information processing. We investigated whether the alternation rate of the perception of a Necker cube depended on the degree of synchronization between two streams of spikes,...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.26778v1
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