Preprints (not yet peer-reviewed)

70 downloads
125 views

Borderline Personality Disorder (BPD) is a complex psychological condition characterised by affective instability, cognitive impairment, problematic behaviours and social dysfunction. Due to the variability in symptomatic profiles, efforts have recently been directed...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27414v1
31 downloads
65 views

Introduction Social isolation induces depressive-like behavior in animals and humans by impacting RNA editing, but the detailed mechanisms are still unknown. The purpose of this study was to explore how an ADAR1 (RNA-editing enzyme) inducer and inhibitor may impact...

["Animal Behavior","Neuroscience","Zoology","Psychiatry and Psychology","Environmental Impacts"]
doi:10.7287/peerj.preprints.27413v1
47 downloads
81 views

Many Zika virus (ZIKV) pathogenesis-related studies have focused primarily on virus-driven pathology and neurotoxicity, instead of considering the possibility of pathogenesis as an (unintended) consequence of host innate immunity: specifically, as the side-effect...

["Bioinformatics","Neuroscience","Virology","Global Health","Infectious Diseases"]
doi:10.7287/peerj.preprints.27401v1
50 downloads
105 views

Crowding research has become a hotbed of vision research and some fundamentals are now widely agreed upon. It is highly likely that you would agree with the following statements. 1) Bouma’s Law can be sensibly stated as saying that ‘critical distance for crowding...

["Computational Biology","Neuroscience","Anatomy and Physiology","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27353v1
60 downloads
103 views

Multiple associative learning events can take place within sub-second time and the "completed" mechanism can then be used for specific memory retrieval without any lapse of time. This indicates that a biological process is completed within the matching time-scales...

["Animal Behavior","Biophysics","Neuroscience","Cognitive Disorders","Computational Science"]
doi:10.7287/peerj.preprints.27343v1
447 downloads
533 views

A long-standing goal in neuroscience has been to bring together neuronal recordings and neural network modeling to understand brain function. Neuronal recordings can inform the development of network models, and network models can in turn provide predictions for...

["Neuroscience","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27340v1
40 downloads
123 views

We propose a biologically-inspired research agenda with parallel tracks aimed at AI and AI safety. The bottom-up component consists of building a sequence of biophysically realistic simulations of simple organisms such as the nematode Caenorhabditis elegans, the...

["Animal Behavior","Computational Biology","Entomology","Neuroscience","Zoology"]
doi:10.7287/peerj.preprints.27321v1
238 downloads
315 views

Possible combinations of inputs in the order of 10100 can fire (axonal spike or action potential) a neuron that has nearly 104 inputs (dendritic spines). This extreme degeneracy of inputs that can fire a neuron is associated with significant loss of information...

["Biophysics","Computational Biology","Neuroscience","Cognitive Disorders","Computational Science"]
doi:10.7287/peerj.preprints.27228v4
61 downloads
103 views

Forming generalizations from previous experiences is a complex skill, which requires a delicate coordination between several basic cognitive abilities. In menacing situations, this ability is called “fear generalization”. It allows humans to predict harmful events...

["Animal Behavior","Computational Biology","Neuroscience","Cognitive Disorders","Computational Science"]
doi:10.7287/peerj.preprints.27311v1
74 downloads
169 views

Crowding research has become a hotbed of vision research and some fundamentals are now widely agreed upon. You would agree with the following statements – wouldn’t you? 1) Bouma’s Law can be sensibly stated as saying that ‘critical distance for crowding is about...

["Neuroscience","Anatomy and Physiology","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27250v1
80 downloads
164 views

Optogenetics is revolutionizing neuroscience but an often neglected effect of light stimulation of the brain is the generation of heat. In extreme cases, light-generated heat kills neurons but mild temperature changes alter neuronal function. In this work, we investigated...

["Molecular Biology","Neuroscience"]
doi:10.7287/peerj.preprints.27248v1
475 downloads
425 views

In the fifty years since Evarts first recorded single neurons in motor cortex of behaving monkeys, great effort has been devoted to understanding their relation to movement. Yet these single neurons exist within a vast network, the nature of which has been largely...

["Bioengineering","Neuroscience","Computational Science","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27217v1
104 downloads
200 views

It has been proposed that the brain processes quantities such as space, size, number, and other magnitudes using a common neural metric, and that this common representation system reflects a direct link to motor control, because the integration of spatial, temporal,...

["Neuroscience","Kinesiology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27194v1
228 downloads
512 views

Human body sense is surprisingly flexible – precisely administered multisensory stimulation may result in the illusion that an external object is part of one’s body. There seems to be a general consensus that there are certain top-down constraints on which objects...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27136v1
176 downloads
450 views

The ability of vertebrates to generate rhythm within their spinal neural networks is essential for walking, running, and other rhythmic behaviors. The central pattern generator (CPG) network responsible for these behaviors is well-characterized with experimental...

["Animal Behavior","Bioinformatics","Computational Biology","Neuroscience","Computational Science"]
doi:10.7287/peerj.preprints.26734v2
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