Preprints (not yet peer-reviewed)

35 downloads
69 views

Describing cell morphology is a tricky task, prone to misinterpretation due to subjective nature of the human observer and his vocabulary limitations. Consequently, these limitations actuate prevalence of non-formalized, statistically unverifiable language use....

["Bioinformatics","Cell Biology","Computational Biology","Marine Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.27271v2
20 downloads
58 views

Background. Following recent advances in bioimaging, high-resolution 3D models of biological structures are now generated rapidly and at low-cost. To utilise this data to address evolutionary and ecological questions, an array of tools has been developed to conduct...

["Computational Biology","Evolutionary Studies","Mathematical Biology"]
doi:10.7287/peerj.preprints.27270v1
152 downloads
323 views

Seasonality is an important feature of essentially all natural systems but the consequences of seasonality have been vastly underappreciated. Early work emphasized the role of seasonality in driving cyclic population dynamics, but the consequences of seasonality...

["Ecology","Mathematical Biology"]
doi:10.7287/peerj.preprints.27235v1
225 downloads
463 views

The sixth mass extinction poses an unparalleled quantitative challenge to conservation biologists. Mathematicians and ecologists alike face the problem of developing models that can scale predictions of extinction rates from populations to the level of a species,...

["Conservation Biology","Ecology","Mathematical Biology","Statistics","Climate Change Biology"]
doi:10.7287/peerj.preprints.3367v2
188 downloads
337 views

The general purpose of this paper is to build up on our understanding of the basic mathematical principles that underlie the emergence of synchronous biological rhythms, in particular, the circadian clock. To do so, we study the role that the coupling strength,...

["Computational Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.26447v2
46 downloads
172 views

Background. The time distribution of biological phenomena (phenology) is a subject of wide interest, but a general statistical distribution to describe and quantify its essential properties is lacking. Existing distributions are limiting, if not entirely inappropriate,...

["Mathematical Biology","Population Biology"]
doi:10.7287/peerj.preprints.27175v1
40 downloads
73 views

The Bertalanffy-Pütter growth model describes mass m at age t by means of the differential equation dm/dt = p⋅ma−q⋅mb. The special case using the Bertalanffy exponent-pair a=2/3 and b=1 is most common (it corresponds to the von Bertalanffy growth function VBGF...

["Aquaculture, Fisheries and Fish Science","Computational Biology","Marine Biology","Mathematical Biology","Computational Science"]
doi:10.7287/peerj.preprints.27152v1
78 downloads
175 views

Background. Mesenchymal stem/stromal cells (MSCs) are a promising tool for cell-based therapies in the treatment of tissue injury. The stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4) axis plays a significant role in directing MSC homing to...

["Cell Biology","Mathematical Biology","Drugs and Devices"]
doi:10.7287/peerj.preprints.27144v1
66 downloads
131 views

In genetic studies, quantitative traits are found possibly associated with genetic data. Due to advanced sequencing technology, many methods have been proposed in genome wide association study (GWAS) to search the single nucleotide polymorphism (SNP) associated...

["Bioinformatics","Mathematical Biology","Statistics"]
doi:10.7287/peerj.preprints.27118v2
447 downloads
797 views

The classical way of defining enzyme inhibition has obscured the distinction between inhibitory effect and the inhibitor binding constant. This article examines the relationship between the simple binding curve used to define biomolecular interactions and the standard...

["Biochemistry","Computational Biology","Mathematical Biology","Drugs and Devices","Pharmacology"]
doi:10.7287/peerj.preprints.3094v2
69 downloads
191 views

Identifying the best framework for two-choice decision-making has been a goal of psychology theory for many decades (Bohil, Szalma, & Hancock, 2015; Macmillan & Creelman, 1991). There are two main candidates: the theory of signal detectability (TSD) (Swets, Tanner...

["Mathematical Biology","Neuroscience","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.26978v1
153 downloads
123 views

According to the energy supply/energy depletion model, it is not clear how the depletion of substrates (adenosine triphosphate) affects sprint performance. Therefore, this research was conducted to find out how the human organism regulates the amount and the rate...

["Computational Biology","Mathematical Biology","Global Health","Kinesiology","Nutrition"]
doi:10.7287/peerj.preprints.26919v1
88 downloads
157 views

Ecologists often analyze relative abundances, which are compositions (sets of non-negative numbers with a fixed sum). However, they have made surprisingly little use of recent advances in the field of compositional data analysis. Compositions form a vector space...

["Ecology","Marine Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.26908v1
598 downloads
1,585 views

Physiological mechanisms for passive and active transmembrane transport have been theoretically described using many different approaches. A generic formulation for both passive and active transmembrane transport, is derived from basic thermodynamical principles...

["Biophysics","Mathematical Biology","Neuroscience"]
doi:10.7287/peerj.preprints.1312v8
75 downloads
217 views

Sclerochronology is presented as an approach to reconstruct, from linear growth records, environmental conditions. This was proposed by analogy with dendrochronology, but shells differ from trees since shells increase in size by terminal, instead of radial, growth....

["Developmental Biology","Ecology","Evolutionary Studies","Mathematical Biology","Environmental Impacts"]
doi:10.7287/peerj.preprints.26827v1
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