Preprints (not yet peer-reviewed)

25 downloads
73 views

Background: To date, the theoretical bases of Lewis’s law and Aboav-Weaire’s law are still unclear. Methods: Software R with package Conicfit was used to fit ellipses based on geometric parameters of polygonal cells of red alga Pyropia haitanensis. Results: The...

["Cell Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.27421v1
189 downloads
226 views

Some marine microparasitic pathogens can survive several months outside the host in the water column to make contact with hosts or to be absorbed or filtered by hosts. Once inside, pathogens invade the host if they find suitable conditions for reproduction within...

["Ecology","Marine Biology","Mathematical Biology","Parasitology","Infectious Diseases"]
doi:10.7287/peerj.preprints.26454v3
28 downloads
98 views

To compare multiple genome sequences, we transform each primary genome sequence into corresponding k-mer-based vectors. According to the principle of independent component analysis (ICA), the operation can be regarded as mixing multiple source genomic signals via...

["Bioinformatics","Computational Biology","Genomics","Mathematical Biology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27333v1
53 downloads
123 views

Describing cell morphology is a tricky task, prone to misinterpretation due to subjective nature of the human observer and his vocabulary limitations. Consequently, these limitations actuate prevalence of non-formalized, statistically unverifiable language use....

["Bioinformatics","Cell Biology","Computational Biology","Marine Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.27271v2
64 downloads
124 views

Background. Following recent advances in bioimaging, high-resolution 3D models of biological structures are now generated rapidly and at low-cost. To utilise this data to address evolutionary and ecological questions, an array of tools has been developed to conduct...

["Computational Biology","Evolutionary Studies","Mathematical Biology"]
doi:10.7287/peerj.preprints.27270v1
265 downloads
415 views

Seasonality is an important feature of essentially all natural systems but the consequences of seasonality have been vastly underappreciated. Early work emphasized the role of seasonality in driving cyclic population dynamics, but the consequences of seasonality...

["Ecology","Mathematical Biology"]
doi:10.7287/peerj.preprints.27235v1
356 downloads
503 views

The sixth mass extinction poses an unparalleled quantitative challenge to conservation biologists. Mathematicians and ecologists alike face the problem of developing models that can scale predictions of extinction rates from populations to the level of a species,...

["Conservation Biology","Ecology","Mathematical Biology","Statistics","Climate Change Biology"]
doi:10.7287/peerj.preprints.3367v2
223 downloads
386 views

The general purpose of this paper is to build up on our understanding of the basic mathematical principles that underlie the emergence of synchronous biological rhythms, in particular, the circadian clock. To do so, we study the role that the coupling strength,...

["Computational Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.26447v2
76 downloads
205 views

Background. The time distribution of biological phenomena (phenology) is a subject of wide interest, but a general statistical distribution to describe and quantify its essential properties is lacking. Existing distributions are limiting, if not entirely inappropriate,...

["Mathematical Biology","Population Biology"]
doi:10.7287/peerj.preprints.27175v1
56 downloads
99 views

The Bertalanffy-Pütter growth model describes mass m at age t by means of the differential equation dm/dt = p⋅ma−q⋅mb. The special case using the Bertalanffy exponent-pair a=2/3 and b=1 is most common (it corresponds to the von Bertalanffy growth function VBGF...

["Aquaculture, Fisheries and Fish Science","Computational Biology","Marine Biology","Mathematical Biology","Computational Science"]
doi:10.7287/peerj.preprints.27152v1
102 downloads
207 views

Background. Mesenchymal stem/stromal cells (MSCs) are a promising tool for cell-based therapies in the treatment of tissue injury. The stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4) axis plays a significant role in directing MSC homing to...

["Cell Biology","Mathematical Biology","Drugs and Devices"]
doi:10.7287/peerj.preprints.27144v1
71 downloads
142 views

In genetic studies, quantitative traits are found possibly associated with genetic data. Due to advanced sequencing technology, many methods have been proposed in genome wide association study (GWAS) to search the single nucleotide polymorphism (SNP) associated...

["Bioinformatics","Mathematical Biology","Statistics"]
doi:10.7287/peerj.preprints.27118v2
517 downloads
846 views

The classical way of defining enzyme inhibition has obscured the distinction between inhibitory effect and the inhibitor binding constant. This article examines the relationship between the simple binding curve used to define biomolecular interactions and the standard...

["Biochemistry","Computational Biology","Mathematical Biology","Drugs and Devices","Pharmacology"]
doi:10.7287/peerj.preprints.3094v2
88 downloads
214 views

Identifying the best framework for two-choice decision-making has been a goal of psychology theory for many decades (Bohil, Szalma, & Hancock, 2015; Macmillan & Creelman, 1991). There are two main candidates: the theory of signal detectability (TSD) (Swets, Tanner...

["Mathematical Biology","Neuroscience","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.26978v1
237 downloads
141 views

According to the energy supply/energy depletion model, it is not clear how the depletion of substrates (adenosine triphosphate) affects sprint performance. Therefore, this research was conducted to find out how the human organism regulates the amount and the rate...

["Computational Biology","Mathematical Biology","Global Health","Kinesiology","Nutrition"]
doi:10.7287/peerj.preprints.26919v1
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