Preprints (not yet peer-reviewed)

284 downloads
608 views

Vertebrate bone is composed of three main cell types, the most prominent of which are the osteocytes. These cells are thought to play a fundamental role in bone physiology, however they are entirely absent in most extant species of teleosts, a group that comprises...

["Aquaculture, Fisheries and Fish Science","Evolutionary Studies","Paleontology","Zoology","Histology"]
doi:10.7287/peerj.preprints.27406v1
39 downloads
100 views

Background. The fibronectin type 3 and ankyrin repeat domains 1 gene, Fank1, is an ancient, evolutionarily conserved gene present in vertebrates. Fank1-knockdown mice have oligospermia caused by an increase in apoptotic germ cells. In this study, we investigated...

["Andrology","Histology"]
doi:10.7287/peerj.preprints.27356v1
181 downloads
750 views

Background. Ampelisca eschrichtii Krøyer, 1842 of the Sakhalin Shelf of the Okhotsk Sea, Far Eastern Russia, comprise the highest known biomass concentration of any amphipod population in the world and are a critically important prey source for western gray whales....

["Conservation Biology","Ecology","Marine Biology","Zoology","Histology"]
doi:10.7287/peerj.preprints.3496v3
89 downloads
174 views

The results in this paper demonstrate that Ishikawa endometrial monolayer cells become multinucleated by a process of nuclear “donation” from neighboring cells. As the resulting polyploid cell detaches from the colony in which it was formed, it is possible to detect...

["Cell Biology","Developmental Biology","Histology"]
doi:10.7287/peerj.preprints.26793v1
172 downloads
250 views

Calcium signaling and body temperature are two important factors governing activation of immune cells. However, molecular identities of major players involved in such critical regulations are still unknown, especially in avian systems. In this work we explored...

["Cell Biology","Immunology","Histology"]
doi:10.7287/peerj.preprints.26614v1
64 downloads
154 views

Myotendinous junction (MTJ) is the largest area of force transmission between skeletal muscle and bone tissue, which is directly associated with physical exercise that possible promotes morphological changes in muscle and tendon tissues. The aim of this study is...

["Geriatrics","Histology"]
doi:10.7287/peerj.preprints.26601v1
151 downloads
433 views

Objective. In the foveola of the eye, photoreceptors and Müller cells with a unique morphology have been described, but little is known about their 3D structure and orientation. Considering that there is an angle-dependent change in the foveolar photoreceptor response...

["Biophysics","Cell Biology","Anatomy and Physiology","Ophthalmology","Histology"]
doi:10.7287/peerj.preprints.26518v1
268 downloads
447 views

Background. The sustainable methods of propagation for Typha domingensis through somatic embryogenesis can help to mitigate its current condition of ecological marginalisation and overexploitation. Then, the hypothesis established that the variation of the concentration...

["Biotechnology","Developmental Biology","Plant Science","Histology","Freshwater Biology"]
doi:10.7287/peerj.preprints.26459v1
963 downloads
1,707 views

Here we provide a detailed description of the postcranial skeleton of the holotype and referred specimens of Buitreraptor gonzalezorum. This taxon was recovered as a unenlagiine dromaeosaurid in several recent phylogenetic studies and is the best represented Gondwanan...

["Paleontology","Taxonomy","Histology"]
doi:10.7287/peerj.preprints.26450v1
286 downloads
450 views

The compound eye is the primary visual system in crustaceans. Although the histological structure and histochemical characteristics of compound eyes of some insect and crab species are now well understood, no such studies have been undertaken in the whiteleg shrimp...

["Aquaculture, Fisheries and Fish Science","Anatomy and Physiology","Ophthalmology","Pathology","Histology"]
doi:10.7287/peerj.preprints.3453v1
99 downloads
421 views

Background. Type 2 diabetes, a chronic disease to which susceptibility is hereditary, is characterized by insulin resistance accompanied by defective insulin secretion. Mouse models, especially transgenic mice, play an important role in medical research. However,...

["Agricultural Science","Biotechnology","Diabetes and Endocrinology","Histology","Medical Genetics"]
doi:10.7287/peerj.preprints.3437v1
106 downloads
574 views

Background: Standard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, proliferation...

["Cell Biology","Histology"]
doi:10.7287/peerj.preprints.2984v1
99 downloads
426 views

Insecticidal crystal (Cry) proteins produced by the bacterium Bacillus thuringiensis (Bt) target cells in the midgut epithelium of susceptible larvae. While the mode of action of Cry toxins has been extensively investigated, the midgut response to Cry intoxication...

["Entomology","Microbiology","Histology"]
doi:10.7287/peerj.preprints.2878v1
136 downloads
285 views

Cancer spread away from the primary tumour towards other parts of the body is what is most feared in cancer treatment, and is the leading cause of relapse for patients who are in remission after initial rounds of treatment with surgery, radiation or chemotherapy....

["Biochemistry","Cell Biology","Marine Biology","Molecular Biology","Histology"]
doi:10.7287/peerj.preprints.2800v1
1,241 downloads
1,023 views

Divergence of treatment responses to chemotherapy exists across patients (often with unknown underlying mechanisms), with some patients exhibiting worsened outcome upon treatment. Genomic approaches (such as microarray profiling and whole genome sequencing) hold...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v6
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