Preprints (not yet peer-reviewed)

56 downloads
227 views

Translational models that utilize omics data generated in in vitro studies to predict the drug efficacy of anti-cancer compounds in patients are highly distinct, which complicates the benchmarking process for new computational approaches. In reaction to this, we...

["Computational Biology","Genomics","Statistics","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27256v1
98 downloads
201 views

The ability of certain natural species to restore or regenerate missing structures has been a recurrent source of inspiration to forge our collective knowledge, from being used to adorn mythological figures with superhuman powers to permitting controlled reproducible...

["Developmental Biology","Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.27255v1
45 downloads
167 views

The gut microbiota has been shown to have an important influence on host health. Microbial composition of the gut microbiota is modulated by diet and human habits. The composition of human gut microbiota changes with age; and alterations in this composition may...

["Biotechnology","Genomics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.27252v1
69 downloads
194 views

Background: It is estimated that 13% of arthropod species carry the heritable symbiont Cardinium hertigii. 16S rRNA and gyrB sequence divides this species into three clades, with the A group infecting a range of arthropods, the B group infecting nematode worms,...

["Evolutionary Studies","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.27242v1
129 downloads
188 views

The owlflies (Family Ascalaphidae) belong to the Neuroptera but are often mistaken as dragonflies because of morphological characters. To date, only three mitochondrial genomes of Ascalaphidae, namely Libelloides macaronius; Ascaloptynx appendiculatus; Ascalohybris...

["Entomology","Genomics","Molecular Biology"]
doi:10.7287/peerj.preprints.27183v2
323 downloads
780 views

Pathway and cell-type signatures are patterns present in transcriptome data that are associated with biological processes or phenotypic consequences. These signatures result from specific cell-type and pathway expression, but can require large transcriptomic compendia...

["Bioinformatics","Computational Biology","Genomics","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27229v1
60 downloads
238 views

Complete mitochondrial genomes of Indian tent turtle, Pangshura tentoria was sequenced and annotated as 16,657 bp in length. This first assembly was encoded by 37 genes: 13 protein coding genes (PCGs), 22 transfer RNA (tRNAs), two ribosomal RNA (rRNAs) as similar...

["Genomics","Zoology"]
doi:10.7287/peerj.preprints.27202v1
52 downloads
124 views

Motivation: The identification of functional sequence variations in regulatory DNA regions is one of the major challenges of modern genetics. Here, we report results of a combined multifactor analysis of properties characterizing functional sequence variants located...

["Bioinformatics","Genomics","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27199v1
59 downloads
220 views

Helicobacter pylori is a human pathogenic bacterium with a high genomic plasticity. Although the functional CRISPR-Cas system has not been found in its genome, CRISPR like loci have been recently identified. In this work, 53 genomes from different geographical...

["Bioinformatics","Evolutionary Studies","Genetics","Genomics"]
doi:10.7287/peerj.preprints.27196v1
33 downloads
106 views

MADS-box genes encode transcription factors that participate in various plant growth and development processes, particularly floral organogenesis. To date, MADS-box genes have been reported in many species, the completion of the sequence of the willow genome provides...

["Bioinformatics","Genomics"]
doi:10.7287/peerj.preprints.27195v1
43 downloads
138 views

The pig is a well studied model animal of biomedical and agricultural importance. Genes of this species, Sus scrofa, are known from experiments and predictions, and collected at the NCBI Reference Sequence database section. Gene reconstruction from transcribed...

["Agricultural Science","Bioinformatics","Genomics","Data Science"]
doi:10.7287/peerj.preprints.27191v1
141 downloads
200 views

Maize is an excellent model for the study of plant adaptation. Indeed, post domestication maize quickly adapted to a host of new environments across the globe. And work over the last decade has begun to highlight the role of the wild relatives of maize – the teosintes...

["Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.27190v1
19 downloads
91 views

Complete genome sequence of new virulent actinophages belonging to Streptomyces flavovirens We report biological and physiochemical features and use NGS to provide the complete annotated genomes for two new strains (Sf1 and Sf3) of the virulent phage Streptomyces...

["Genomics","Microbiology","Virology"]
doi:10.7287/peerj.preprints.27186v1
44 downloads
139 views

Next Generation Sequencing (NGS) technologies provide unique possibilities for the comprehensive assessment of the environmental diversity of bacteriophages. Several Bacillus bacteriophages have been isolated, but very few Bacillus megaterium bacteriophages have...

["Agricultural Science","Bioinformatics","Genomics","Microbiology","Virology"]
doi:10.7287/peerj.preprints.27171v1
205 downloads
478 views

ABSTRACT: The discovery of Paranthropus deyiremeda in 3.3–3.5 million year old fossil sites in Afar, together with 30% of the gorilla genome showing lineage sorting between humans and chimpanzees, and a NUMT (“nuclear mitochondrial DNA segment”) on chromosome 5...

["Anthropology","Evolutionary Studies","Genomics","Paleontology"]
doi:10.7287/peerj.preprints.27163v1
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