Preprints (not yet peer-reviewed)

405 downloads
907 views

Many pressing medical challenges - such as diagnosing disease, enhancing directed stem cell differentiation, and classifying cancers - have long been hindered by limitations in our ability to quantify proteins in single cells. Mass-spectrometry (MS) is poised to...

["Bioengineering","Biotechnology","Cell Biology","Computational Biology","Genomics"]
doi:10.7287/peerj.preprints.26821v2
245 downloads
702 views

Horizontal gene transfer has had major impacts on the biology of a wide range of organisms from antibiotic resistance in bacteria to adaptations to herbivory in arthropods. A growing body of literature shows that horizontal gene transfer (HGT) between non-animals...

["Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.3462v3
128 downloads
257 views

Bacteria and other microbes play a crucial role in human health and disease. Medicine and clinical microbiology have traditionally attempted to identify the etiological agents that causes disease, and how to eliminate them. Yet this traditional paradigm is becoming...

["Ecology","Evolutionary Studies","Genomics","Infectious Diseases","Translational Medicine"]
doi:10.7287/peerj.preprints.26969v2
84 downloads
468 views

Background. Carnivorous plants have been fascinating researchers with their unique characters and bioinspired applications. These include medicinal trait of some carnivorous plants with potentials for pharmaceutical industry. Methods. This review will cover recent...

["Biochemistry","Biotechnology","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26940v1
83 downloads
108 views

A major obstacle to high-throughput genotyping of micro-hymenoptera is their small size. As species are difficult to discriminate and because complexes may exist, the sequencing of a pool of specimens is hazardous. Thus, one should be able to sequence pangenomic...

["Biodiversity","Entomology","Genomics","Molecular Biology","Taxonomy"]
doi:10.7287/peerj.preprints.26939v1
146 downloads
480 views

Background. Comparative genomics between closely related bacterial strains can distinguish important features determining pathogenesis, antibiotic resistance, and phylogenetic structure. The Streptococcus genus is relevant to public health and food safety and it...

["Biodiversity","Bioinformatics","Genomics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.26665v2
178 downloads
887 views

Studies involving gut microbiome analysis play an increasing role in the evaluation of health and disease in humans and animals alike. Fecal sampling methods for DNA preservation in laboratory, clinical, and field settings can greatly influence inferences of microbial...

["Biodiversity","Bioinformatics","Genomics","Microbiology","Veterinary Medicine"]
doi:10.7287/peerj.preprints.26912v1
145 downloads
211 views

Fish are sensitive to temperature, but the intergenerational consequences of maternal exposure to high temperature on offspring adaptive behaviour and underlying mechanisms are unknown. Here we show that a thermal maternal stress induces emotional and cognitive...

["Animal Behavior","Aquaculture, Fisheries and Fish Science","Developmental Biology","Genomics","Climate Change Biology"]
doi:10.7287/peerj.preprints.26910v1
89 downloads
326 views

Sweet potato is a major food security crop within sub-Saharan Africa where 90 % of Africa’s sweet potato production occurs. One of the major limitations of sweet potato production are viral infections. In this study, we used a combination of whole genome sequences...

["Agricultural Science","Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.26909v1
47 downloads
164 views

Background: Endornaviruses are non-pathogenic viruses infecting multiple agricultural important crops including legumes, with global distribution. However, there is an absence on the complete genome of endornaviruses from legumes in particular with the sub-Saharan...

["Agricultural Science","Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.26904v1
396 downloads
1,166 views

Low-cost Illumina sequencing of clinically-important bacterial pathogens has generated thousands of publicly available genomic datasets. Analyzing these genomes and extracting relevant information for each pathogen and the associated clinical phenotypes requires...

["Bioinformatics","Genomics","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.26890v2
61 downloads
115 views

Xeno-miRNAs are microRNAs originating from exogenous species detected in host biofluids. A growing number of studies have suggested that many of these xeno-miRNAs may be involved in cross-species interactions by targeting host mRNAs. To date, hundreds of xeno-miRNAs...

["Bioinformatics","Computational Biology","Genetics","Genomics","Parasitology"]
doi:10.7287/peerj.preprints.26887v1
429 downloads
1,152 views

Research in Arabidopsis and other model species has uncovered mechanisms regulating important biological processes in plants. With the advent of high quality functional genomic resources in wheat it is now possible to use this knowledge for crop improvement directly...

["Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26877v1
92 downloads
255 views

Strawberry (Fragaria × ananassa) is an ideal plant for fruit development and ripening research due to the rapid substantial changes in fruit color, aroma, taste and softening. To gain deeper insights into the genes that play a central regulatory role in strawberry...

["Bioinformatics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26870v1
200 downloads
591 views

Background. Cytoplasmic male sterility (CMS) is a common phenotype in higher plants, which often is associated with rearrangements in mitochondrial DNA (mtDNA), and is widely used to produce hybrid seeds in a variety of valuable crop species. The CMS phenomenon...

["Agricultural Science","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26438v2
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