Preprints (not yet peer-reviewed)

17 downloads
55 views

This detailed analysis provides an insight into aging processes in the human organism. The developmental program that controls the regulation of gene expression through epigenetic modifications leads to cellular senescence in the latter life. This epigenetic development...

["Cell Biology","Developmental Biology","Genetics","Molecular Biology"]
doi:10.7287/peerj.preprints.26998v1
43 downloads
339 views

Human primary T cells are invaluable and feasible model systems to study the characteristics of the immune cells in various contexts, including but not limited to cancer immunotherapy. Following isolation of T cells from fresh human blood samples, it is possible...

["Cell Biology","Genetics","Molecular Biology","Immunology"]
doi:10.7287/peerj.preprints.26993v1
412 downloads
721 views

Domestication is a tractable system for following evolutionary change. Under domestication, wild populations respond to shifting selective pressures, resulting in adaptation to the new ecological niche of cultivation. Due to the important role of domesticated crops...

["Evolutionary Studies","Genetics"]
doi:10.7287/peerj.preprints.26502v2
180 downloads
583 views

If the environmental conditions can or not influence in the phenotype evolution, is a topic that has been discussed during the last ten years. The epigenome regulates the gene expression of all cells and indicates which specific genes must be transcribed. It is...

["Animal Behavior","Ecology","Evolutionary Studies","Genetics"]
doi:10.7287/peerj.preprints.26862v7
103 downloads
497 views

Vervet monkeys (Chlorocebus pygerythrus) are one of the most widely distributed non-human primate species found in South Africa. They occur across all the South African provinces, inhabiting a large variety of habitats. These habitats vary sufficiently that it...

["Anthropology","Biodiversity","Biogeography","Genetics"]
doi:10.7287/peerj.preprints.26577v4
89 downloads
261 views

Background Antimicrobial compounds released by the entomopathogenic nematode-symbiont bacterium Xenorhabdus budapestensis (EMA) are oligopeptides and the "trump" is fabclavine. They kill antibiotic multi-resistant Escherichia coli, Salmonella; mastitis-isolate...

["Genetics","Microbiology"]
doi:10.7287/peerj.preprints.26900v1
69 downloads
201 views

Background. The captive cetacean industry is very profitable and popular worldwide, focusing mainly on leisure activities such as “Swim-with-dolphins” (SWD) programs. However, there is a concern for how captivity could affect the bottlenose dolphin Tursiops truncatus,...

["Conservation Biology","Genetics","Marine Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.26891v1
71 downloads
117 views

Xeno-miRNAs are microRNAs originating from exogenous species detected in host biofluids. A growing number of studies have suggested that many of these xeno-miRNAs may be involved in cross-species interactions by targeting host mRNAs. To date, hundreds of xeno-miRNAs...

["Bioinformatics","Computational Biology","Genetics","Genomics","Parasitology"]
doi:10.7287/peerj.preprints.26887v1
204 downloads
600 views

Background. Cytoplasmic male sterility (CMS) is a common phenotype in higher plants, which often is associated with rearrangements in mitochondrial DNA (mtDNA), and is widely used to produce hybrid seeds in a variety of valuable crop species. The CMS phenomenon...

["Agricultural Science","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26438v2
1,463 downloads
4,257 views

Almost a decade ago, the sequencing of ancient DNA from archaic humans - Neanderthals and Denisovans - revealed that modern and archaic humans interbred at least twice during the Pleistocene. The field of human paleogenomics has now turned its attention towards...

["Anthropology","Evolutionary Studies","Genetics","Genomics"]
doi:10.7287/peerj.preprints.26782v2
96 downloads
289 views

Metabarcoding studies often employ degenerate primers to reduce amplification bias and increase the number of detected taxa. However, degeneracy has the disadvantage of lowering binding specificity although the exact mechanisms and potential biases introduced by...

["Biochemistry","Bioinformatics","Genetics","Molecular Biology"]
doi:10.7287/peerj.preprints.26763v1
54 downloads
160 views

Time-resolved phylogenetic methods use information about the time of sample collection to estimate the rate of evolution. Originally, the models used to estimate evolutionary rates were quite simple, assuming that all lineages evolve at the same rate, an assumption...

["Bioinformatics","Genetics","Computational Science"]
doi:10.7287/peerj.preprints.26744v1
51 downloads
126 views

Habitat fragmentation is one of the main threats to the biodiversity and one of the main challenges faced by conservation biology. This study assessed the effects of habitat fragmentation on the genetic variability of the blue manakin Chiroxiphia caudata, an endemic...

["Conservation Biology","Genetics"]
doi:10.7287/peerj.preprints.26742v1
74 downloads
214 views

Background. Telomeres in Drosophila melanogaster are similar to those of other eukaryotes in terms of their function, although they are formed by non-LTR retrotransposons instead of telomerase-based short repeats. The length of the telomeres in Drosophila depends...

["Genetics"]
doi:10.7287/peerj.preprints.26708v1
110 downloads
221 views

Mycelial compatibility, the ability for fungal isolates to grow together and form one single colony, was defined for Sclerotinia sclerotiorum nearly 30 years ago and has since been used as a marker to describe clonal variation in population genetic studies. While...

["Agricultural Science","Genetics","Mycology","Population Biology"]
doi:10.7287/peerj.preprints.26670v1
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