Preprints (not yet peer-reviewed)

97 downloads
216 views

This article reports on a conference workshop conducted at CYTO 2018. During the workshop a new Open Science forum "CYTO Lab Hacks" has been launched within the International Society for the Advancement of Cytometry (ISAC). Its goal is to serve as an open, transparent,...

["Cell Biology","Science Policy"]
doi:10.7287/peerj.preprints.27300v3
25 downloads
73 views

Background: To date, the theoretical bases of Lewis’s law and Aboav-Weaire’s law are still unclear. Methods: Software R with package Conicfit was used to fit ellipses based on geometric parameters of polygonal cells of red alga Pyropia haitanensis. Results: The...

["Cell Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.27421v1
116 downloads
69 views

Objectives. Grb2-associated binder 1 (Gab1), a scaffolding adaptor protein, plays an important role in transmitting key signals that control cell growth, migration, and function from multiple tyrosine kinase receptors. This study was designed to investigate the...

["Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.27417v1
33 downloads
95 views

Background: HOXC6 is a member of the HOX gene family. The elevated expression of this gene occurs in prostate and breast cancers. However, the role of HOXC6 in esophageal squamous cell carcinoma (ESCC) remains largely uninvestigated.Methods: The expression of HOXC6...

["Cell Biology","Molecular Biology","Oncology"]
doi:10.7287/peerj.preprints.27324v1
53 downloads
123 views

Describing cell morphology is a tricky task, prone to misinterpretation due to subjective nature of the human observer and his vocabulary limitations. Consequently, these limitations actuate prevalence of non-formalized, statistically unverifiable language use....

["Bioinformatics","Cell Biology","Computational Biology","Marine Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.27271v2
55 downloads
127 views

The fractal formalism in combination with linear image analysis enables statistically significant description and classification of “irregular” (in terms of Euclidean geometry) shapes, such as, outlines of in vitro flattened cells. We developed an optimal model...

["Bioinformatics","Cell Biology","Computational Biology","Marine Biology"]
doi:10.7287/peerj.preprints.27258v1
350 downloads
611 views

The actin cytoskeleton comprises a set of filament networks that perform essential functions in eukaryotic cells. The idea that actin filaments incorporate monomers directly from solution forms both the “textbook picture” of filament elongation and a conventional...

["Biochemistry","Biophysics","Cell Biology"]
doi:10.7287/peerj.preprints.27254v1
80 downloads
219 views

Genomic instability can manifest due to both chromosomal rearrangements and gain and loss of entire chromosomes. One mechanism by which a carcinogen acts is by increasing the rate of mitotic spindle defects during proliferation. These defects can lead to chromosomal...

["Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.27177v1
473 downloads
1,072 views

The microbe-stuffed gut, rather than the genome, represents the most dynamic gene reservoir within complex, multicellular metazoa (animals). Microbes are known to confer increased metabolic efficiency, increased nutrient recovery, and tolerance of ocean acidity...

["Cell Biology","Evolutionary Studies"]
doi:10.7287/peerj.preprints.27173v1
86 downloads
223 views

Background. Insufficient quantities of freshly harvested Limnoperna fortunei gametes and embryos constrain reproduction research in the laboratory. Cryopreservation would allow the accumulation and storage of gametes when they are available. The lack of available...

["Aquaculture, Fisheries and Fish Science","Cell Biology"]
doi:10.7287/peerj.preprints.27165v2
55 downloads
129 views

Tropomodulins (Tmods) are proteins that cap the slow growing (pointed) ends of actin filaments (F-actin). The basis for our current understanding of Tmod function comes from studies in cells with relatively stable and highly organized F-actin networks, leading...

["Biochemistry","Cell Biology","Molecular Biology","Anatomy and Physiology","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.27172v1
102 downloads
207 views

Background. Mesenchymal stem/stromal cells (MSCs) are a promising tool for cell-based therapies in the treatment of tissue injury. The stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4) axis plays a significant role in directing MSC homing to...

["Cell Biology","Mathematical Biology","Drugs and Devices"]
doi:10.7287/peerj.preprints.27144v1
78 downloads
121 views

Microbes live in communities known as biofilm on many surfaces. Thus, understanding the spatially-resolved intercellular communication and signalling link would be important to elucidate the fundamental mechanisms that govern the division of labour within biofilm...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Microbiology"]
doi:10.7287/peerj.preprints.27117v1
51 downloads
141 views

This study focused on the alterations that occur in larval molluscan cells during the induction or inhibition of apoptosis both in standard culture conditions and in response to cold injury during the induction of different death pathways. This is the first report...

["Cell Biology","Marine Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.27100v1
75 downloads
228 views

Programmed cell death signaling networks are frequently activated to coordinate the process of cell differentiation, and a variety of apoptotic events can mediate the process. This can include the ligation of death receptors, the activation of downstream caspases,...

["Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.27080v1
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