Preprints (not yet peer-reviewed)

228 downloads
585 views

Many pressing medical challenges -- such as diagnosing disease, enhancing directed stem cell differentiation, and classifying cancers -- have long been hindered by limitations in our ability to quantify proteins in single cells. Mass-spectrometry (MS) is poised...

["Bioengineering","Biotechnology","Cell Biology","Computational Biology","Genomics"]
doi:10.7287/peerj.preprints.26821v1
28 downloads
185 views

We present PromoterPredict, a dynamic multiple regression approach to predict the strength of Escherichia coli promoters binding the σ70 factor of RNA polymerase. σ70 promoters are ubiquitously used in recombinant DNA technology, but characterizing their strength...

["Bioengineering","Bioinformatics","Biotechnology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.26759v2
13 downloads
66 views

Polyethylene glycol is commonly used in fermentations as an anti-foam for preventing the rise of foam to the top plate of the bioreactor, which increases contamination risk. However, its potential toxicity to growth of various microorganisms is not well understood...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Microbiology"]
doi:10.7287/peerj.preprints.26817v1
27 downloads
108 views

Background. Entolimod is a Salmonella enterica flagellin derivate. Previous work has demonstrated that entolimod effectively protects mice and non-human primates from ionizing radiation. However, it caused a “flu-like” syndrome after radioprotective and anticancer...

["Biochemistry","Bioengineering","Biotechnology"]
doi:10.7287/peerj.preprints.26803v1
28 downloads
88 views

The production of lignocellulosic ethanol is one of the most promising alternatives to fossil fuels, however, this technology still faces many challenges related to the viability of the alcohol in the market. In this paper the endocarp of buriti fruit was assessed...

["Agricultural Science","Bioengineering","Food, Water and Energy Nexus"]
doi:10.7287/peerj.preprints.26777v1
37 downloads
73 views

Background. Brain function requires a coordinated flow of information among functionally specialized areas. Quantitative methods provide a multitude of metrics to quantify the oscillatory interactions measured by invasive or non-invasive recording techniques. Granger...

["Bioengineering","Neuroscience"]
doi:10.7287/peerj.preprints.26703v1
33 downloads
77 views

Currently, a variety of display technologies have been developed in the life science field, such as phage display, ribosome display, and yeast display. Many studies have found that display technologies are powerful and universal methods when they are combined with...

["Bioengineering","Biotechnology","Molecular Biology"]
doi:10.7287/peerj.preprints.26702v1
63 downloads
121 views

Jasmonic acid (JA) and its derivatives (called jasmonates) are lipid-derived signalling molecules that are produced by certain bacteria, fungi and plants. Beside this function, jasmonates have a great variety of applications in the flavour and fragrances production....

["Agricultural Science","Biochemistry","Bioengineering","Biotechnology","Microbiology"]
doi:10.7287/peerj.preprints.26655v1
37 downloads
91 views

Bacterial cell surface carries an electrical charge due to the myriad functional groups present, as well as assortment of ions and molecules nonspecifically adsorbed to the cell surface. Thus, solution in contact with the bacterial cell surface play a critical...

["Biochemistry","Bioengineering","Biotechnology","Microbiology","Biogeochemistry"]
doi:10.7287/peerj.preprints.26626v1
43 downloads
132 views

Cell quantification assays are essential components of most biological and clinical labs. However, many currently available quantification assays, including flow cytometry and commercial cell counting systems, suffer from unique drawbacks that limit their overall...

["Bioengineering","Biotechnology"]
doi:10.7287/peerj.preprints.26584v1
35 downloads
114 views

High cell density cultivation necessitates cell division and biomass formation, the mechanisms of which remain poorly understood, especially from the cellular energetics perspective. Specifically, the sensing of energy abundance and the channelling of nutritional...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Microbiology"]
doi:10.7287/peerj.preprints.26598v1
34 downloads
83 views

This study evaluated the potentials of Fluted pumpkin fruit rind and poultry manure for biogas generation. Mechanical and thermo-alkaline pre-treatments were applied to two samples labelled ‘O’ and ‘P’ while the third sample (Q) had no thermo-alkaline treatment....

["Bioengineering","Biotechnology","Mathematical Biology","Microbiology"]
doi:10.7287/peerj.preprints.26564v1
265 downloads
1,211 views

Lack of colour contrast hampers automated identification of colonies on agar, given that many microbial colonies are of the same colour as the background colour of most agar: beige colour. On the other hand, a colourless agar could increase the colour contrast...

["Biochemistry","Bioengineering","Biotechnology","Ecology","Microbiology"]
doi:10.7287/peerj.preprints.89v6
108 downloads
517 views

Bacterial surface charge derives its meaning from the cell’s environment such as the solution in contact with the cell. Determining the surface charge of bacteria in its native environment requires measuring the proxy variable, zeta potential, using cells obtained...

["Biochemistry","Bioengineering","Biophysics","Biotechnology","Microbiology"]
doi:10.7287/peerj.preprints.2086v4
46 downloads
149 views

Proteins that modify the activity of transcription factor (TF), often called modulators, play a vital role in gene transcriptional regulation. Alternative splicing is a critical step of gene processing and it can modulate gene function by adding or removing certain...

["Bioengineering","Bioinformatics","Biotechnology","Genetics","Computational Science"]
doi:10.7287/peerj.preprints.26482v1
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