Preprints (not yet peer-reviewed)

35 downloads
95 views

Extensive investigations over the recent decades have established the anatomical, biomechanical and functional importance of the meniscus in the knee joint. As a functioning part of the joint, it serves to prevent the deterioration of articular cartilage and subsequent...

["Biotechnology","Kinesiology","Orthopedics"]
doi:10.7287/peerj.preprints.3111v1
68 downloads
127 views

Background. To find a better prophylactic regimen, the pathogenesis of acquired heterotopic ossification (AHO) must be more understood. To date, AHO formation is largely thought to be related to inflammation, which is activated by trauma, resulting in AHO by up-regulation...

["Orthopedics"]
doi:10.7287/peerj.preprints.2709v1
53 downloads
305 views

Bone Morphogenic Protein 2 (BMP2) is a multipurpose cytokine, important in the development of bone and cartilage, and with a role in tumour initiation and progression. Because of BMP2’s osteogenic properties, a recombinant human version (rhBMP2) has found utility...

["Bioinformatics","Cell Biology","Genomics","Drugs and Devices","Orthopedics"]
doi:10.7287/peerj.preprints.1719v1
164 downloads
338 views

The aim of this study was to evaluate if low-frequency, low-magnitude vibrations (LFLM) could enhance chondrogenic differentiation potential of human adipose derived mesenchymal stem cells (hASCs) with simultaneous inhibition of their adipogenic properties for...

["Cell Biology","Molecular Biology","Orthopedics","Science and Medical Education"]
doi:10.7287/peerj.preprints.1514v1
183 downloads
264 views

Objective. To explore whether the image noises and the metal artifacts could be further managed by the combined use of two technologies, the adaptive statistical iterative reconstruction (ASIR) and the monochromatic imaging generated by gemstone spectral imaging...

["Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7287/peerj.preprints.1306v1
403 downloads
514 views

The development of predictive mathematical models can contribute to a deeper understanding of the specific stages of bone mechanobiology and the process by which bone adapts to mechanical forces. The objective of this work was to predict, with spatial accuracy,...

["Bioengineering","Computational Biology","Orthopedics"]
doi:10.7287/peerj.preprints.1140v3
188 downloads
399 views

Over the last two decades the number of total joint replacement surgeries increased consistently. With the patient population growing older and therefore suffering from more comorbidities and total joint replacement being progressively indicated even in patients...

["Anatomy and Physiology","Geriatrics","Orthopedics","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.1119v2
83 downloads
252 views

Force plates are a straightforward tool to assess human acceleration as an indicator of human performance. Understanding of the physical principle, and also of the test instruction is required to arrive at meaingful results and interpretations. Notably, performance...

["Anatomy and Physiology","Geriatrics","Orthopedics"]
doi:10.7287/peerj.preprints.1099v1
160 downloads
373 views

Most people consider walking to be a natural and self-evident activity of everyday life. However, this familiarity turns out to be fragile in the face of the question "Do you know how you walk?" The mechanism of walking has puzzled scientists, doctors and writers...

["Anthropology","Anatomy and Physiology","Neurology","Orthopedics","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.1004v1
170 downloads
404 views

Many people prefer running to keep in shape. In recent years many self-tracking and self-optimization gadgets has become popular especially for running. We are interested in the quality of running because individual running style has an impact on the running performance...

["Bioengineering","Bioinformatics","Anatomy and Physiology","Orthopedics","Computational Science"]
doi:10.7287/peerj.preprints.976v1
532 downloads
224 views

A wide range of techniques on ligament reconstruction have been proposed, summarized in three main categories: The direct suturing or indirect reconstruction of the ligament using adjuvant devices, the “biological ligament ” substitution with the use of autografts...

["Orthopedics"]
doi:10.7287/peerj.preprints.810v1
366 downloads
432 views

In the last years the number of long distance runners who wear minimal footwear or run completely barefoot increased considerably. There is an ongoing debate about the benefits and risks of running in minimal footwear/barefoot instead of running in conventional...

["Bioinformatics","Biophysics","Orthopedics"]
doi:10.7287/peerj.preprints.497v1
77 downloads
463 views

Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous synoviocytes from the affected stifle is an attractive cell source for tissue engineering replacement fibrocartilage. However, the diseased state of these cells may impede in vitro...

["Bioengineering","Cell Biology","Veterinary Medicine","Orthopedics"]
doi:10.7287/peerj.preprints.475v1
698 downloads
584 views

Spiraldynamik ® is an anatomically based movement and therapy concept. It was founded by the physiotherapist Yolanda Deswarte, and Dr. med. Christian Larsen. During the time that he was professionally active as a pediatrician, Christian Larsen repeatedly wondered:...

["Evolutionary Studies","Anatomy and Physiology","Orthopedics","Coupled Natural and Human Systems"]
doi:10.7287/peerj.preprints.383v1
131 downloads
439 views

Background: The individual running style has an impact on the running performance as well as the running injury risk. In order to increase the performance and lower the injury risk, runners should be educated towards a healthy running style. But before advices...

["Bioinformatics","Anatomy and Physiology","Orthopedics","Computational Science"]
doi:10.7287/peerj.preprints.370v1
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