Preprints (not yet peer-reviewed)

13 downloads
237 views

Previous studies have used the zebrafish to investigate the biology of lens crystallin proteins and their roles in development and disease. However, little is known about zebrafish α-crystallin promoter function, how it compares to that of mammals, or whether mammalian...

["Developmental Biology","Molecular Biology","Neuroscience","Ophthalmology"]
doi:10.7287/peerj.preprints.2889v1
42 downloads
134 views

BACKGROUNDː This article describes the characterization of a new cell line (IRB-1), which was established from an Iranian child with retinoblastoma. METHODSː Using cell culture techniques, we isolated a clonal population from primary Cultures of retinoblastoma...

["Cell Biology","Oncology","Ophthalmology"]
doi:10.7287/peerj.preprints.2780v1
40 downloads
195 views

Purpose: To compare the intraoperative angle stability and the postoperative outflow of two ab interno trabeculectomy devices that excise the trabecular meshwork. The newer device has an active aspiration and irrigation port while the older requires viscoelastic...

["Drugs and Devices","Ophthalmology","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.2762v2
80 downloads
249 views

Objective: Trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might represent a novel therapeutic breakthrough. Various decellularized TM scaffolds were developed...

["Bioengineering","Ophthalmology","Statistics"]
doi:10.7287/peerj.preprints.2736v3
32 downloads
160 views

Purpose: Microincisional glaucoma surgeons operate in a highly confined space, making it difficult to learn by observation or assistance alone. We hypothesized that an ex vivo model would allow for better refinement of technique, quantification of progress, and...

["Ophthalmology","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.2745v1
123 downloads
475 views

Measurement of pupil size (pupillometry) has recently gained renewed interest from psychologists, but there is little agreement on how pupil-size data is best analyzed. Here we focus on one aspect of pupillometric analyses: baseline correction, that is, analyzing...

["Neuroscience","Ophthalmology","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2725v1
23 downloads
138 views

Background. Opacities of the lens are typical age related phenomena which have high influence on photoreception and consequently circadian rhythm. In mouse lemurs, a small bodied non-human primate, a high incidence (more than 50% when > 7 years) of cataract has...

["Veterinary Medicine","Ophthalmology"]
doi:10.7287/peerj.preprints.2714v1
79 downloads
364 views

Aim/hypothesis The aim of our study was to characterize the human salivary proteome and determine the changes in protein expression in 2 different stages of diabetic retinopathy with type-2 diabetes mellitus: (1) with non-proliferative diabetic retinopathy (NPDR)...

["Biochemistry","Diabetes and Endocrinology","Ophthalmology"]
doi:10.7287/peerj.preprints.1973v1
392 downloads
423 views

Contact with and handling of burs (the flowering heads or infructescences) from the greater burdock (Arctium lappa L., Asteraceae) and other members of the same genus, is a potential hazard for humans, horses, and dogs. The minute, sharply-pointed, bristly pappus...

["Agricultural Science","Veterinary Medicine","Ophthalmology","Public Health","Science and Medical Education"]
doi:10.7287/peerj.preprints.1871v1
85 downloads
385 views

Introduction: The determinant factors that influence self-reported quality of vision have yet to be fully elucidated. This study evaluated a range of contextual information, established psychophysical tests, and in particular, a series of cognitive tests as potentially...

["Epidemiology","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.738v2
315 downloads
389 views

INTRODUCTION: Diabetic retinopathy affects majority (70% to 90%) of diabetic patients, causes visual impairment which leads to severe psycho-social disruption in life. Our objective was to study the patients of diabetic retinopathy, co-relate between the types...

["Diabetes and Endocrinology","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.981v1
129 downloads
187 views

Background: Blindness and severe visual impairment render affected individuals, families and communities economically, socially and physically disadvantaged. The number of adults ≥ 40 years with severe visual impairment and blindness in Nigeria is projected to...

["Health Policy","Ophthalmology","Public Health"]
doi:10.7287/peerj.preprints.974v1
9,218 downloads
3,982 views

Eye-tracking technology is becoming increasingly cheaper, both on the hardware and on the software front. Currently, the EyeTribe tracker is the most inexpensive commercial eye tracker in the world, at a price of $99. The low costs make it a potentially interesting...

["Neuroscience","Ophthalmology","Psychiatry and Psychology","Human-Computer Interaction"]
doi:10.7287/peerj.preprints.585v1
1,996 downloads
1,632 views

Here we show that the pupillary light response reflects exogenous (involuntary) shifts of attention and inhibition of return. Participants fixated in the center of a display that was divided into a bright and a dark half. An exogenous cue attracted attention to...

["Neuroscience","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.422v1
414 downloads
1,867 views

Why are the retinal color receptors cone-shaped? This is not a trivial question: the cone shape is evidently a universal feature of the color receptors while the achromatic rod receptors are always rod-shaped. What might be behind this dichotomy has not previously...

["Biophysics","Anatomy and Physiology","Ophthalmology"]
doi:10.7287/peerj.preprints.331v1
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