Preprints (not yet peer-reviewed)

139 downloads
311 views

Bacterial vaginosis (BV) is one of most common vaginal infection and its diagnosis by classical methods reveals low specificity. Our goal was to compare the accuracy of BV diagnosis between the gold standard method, Nugent score, and our novel Peptide Nucleic Acid...

["Microbiology","Molecular Biology","Epidemiology","Infectious Diseases","Women's Health"]
doi:10.7287/peerj.preprints.698v1
2,344 downloads
397 views

The success of the proposed HIV testing and counselling (HTC) initiative among learners at high school in South Africa depends on their acceptability of the service, which may be influenced by their HIV/AIDSknowledge, perceptions, and attitudes. The study assessed...

["Epidemiology","Global Health","HIV","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.693v1
209 downloads
346 views

Burul ulcer disease is an infection of the subcutaneous layer. The causative organism, Mycobacterium ulcerans is a slow-growing environmental pathogen often associated with wetland and slow moving streams. One insect order believed to be associated with M.ulcerans...

["Entomology","Microbiology","Epidemiology","Global Health","Infectious Diseases"]
doi:10.7287/peerj.preprints.656v2
293 downloads
717 views

Neisseria gonorrhoeae is the causative agent of gonorrhea, a sexually transmitted infection (STI) of major importance. As a result of antibiotic resistance, there are now limited options for treating patients. We collected whole genome sequences and associated...

["Bioinformatics","Evolutionary Studies","Genomics","Microbiology","Infectious Diseases"]
doi:10.7287/peerj.preprints.636v1
460 downloads
526 views

Planktonic cultures of Mycobacterium tuberculosis, the bacterium responsible for the lung disease tuberculosis (TB), are highly susceptible to killing by ascorbic acid (vitamin C). As planktonically grown M. tuberculosis are unlikely to be representative of the...

["Microbiology","Infectious Diseases"]
doi:10.7287/peerj.preprints.633v1
63 downloads
545 views

If malaria can be eliminated from anywhere it is from isolated areas such as the 2x7 km peninsula of Linga Linga in southern Mozambique. Currently available control strategies include bed nets impregnated with pyrethroid insecticides (long-lasting insecticidal...

["Epidemiology","Global Health","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.630v1
371 downloads
315 views

Rubella is a vaccine-preventable, mild rash-inducing viral disease with complications that include a spectrum of birth defects in the developing foetus, especially if the infection is acquired in the early months of pregnancy. Consequently, the primary objective...

["Epidemiology","Gynecology and Obstetrics","Infectious Diseases","Pediatrics","Women's Health"]
doi:10.7287/peerj.preprints.613v1
72 downloads
286 views

Streptococcus pneumoniae serotype 1 is one of the leading causes of invasive pneumococcal disease. However this invasive serotype is hardly found in nasopharyngeal asymptomatic carriage and therefore large epidemiological studies are needed to assess the dynamics...

["Genomics","Microbiology","Epidemiology","Global Health","Infectious Diseases"]
doi:10.7287/peerj.preprints.611v1
1,782 downloads
463 views

South Asian population suffer a particularly wide range of infectious diseases among which TB and HIV appear to produce most profound influence across various dimensions of social life, healthcare and the economy. Although the countries in this region have a relatively...

["Global Health","Health Policy","HIV","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.579v1
157 downloads
550 views

Background: Emergency department (ED) fever management algorithms require the clinician to categorize febrile children as ‘ill’ or ‘not ill’ appearing when determining the risk for serious bacterial illness (SBI). This study describes a natural experiment where...

["Emergency and Critical Care","Infectious Diseases","Pediatrics"]
doi:10.7287/peerj.preprints.527v1
67 downloads
346 views

We demonstrated that the 3-substituted benzothiophene-1,1-dioxide class of compounds are effective inhibitors of Mycobacterium tuberculosis growth under aerobic conditions. We examined substitution at the C-3 position of the benzothiophene-1,1-dioxide series systematically...

["Microbiology","Global Health","Infectious Diseases"]
doi:10.7287/peerj.preprints.502v1
369 downloads
1,465 views

Tuberculosis remains a major global health problem. Laboratory diagnostic methods that allow effective, early detection of cases are central to management of tuberculosis in the individual patient and in the community. Since the 1880s, laboratory diagnosis of tuberculosis...

["Bioinformatics","Genomics","Microbiology","Infectious Diseases","Respiratory Medicine"]
doi:10.7287/peerj.preprints.482v1
76 downloads
437 views

Acinetobacter baumannii is a nosocomial species frequently isolated from the traumatic wounds of injured military personnel and increasingly detected in civilian healthcare facilities. Many clinical isolates of A. baumannii are drug resistant, so new treatments...

["Ecology","Microbiology","Infectious Diseases"]
doi:10.7287/peerj.preprints.436v1
248 downloads
539 views

The 2014 World Cup Brazil will create excitement around the globe, but viewership in Africa should be especially high after South Africa 2010 and the growing popularity of football. The time difference and scheduling of matches, however, means that 86% of live...

["Ecology","Infectious Diseases"]
doi:10.7287/peerj.preprints.402v1
252 downloads
587 views

HIV disclosure from parent to child is complex and challenging to HIV-positive parents and healthcare professionals. The purpose of the study was to understand the lived experiences of HIV-positive parents and their children during the disclosure process in Kenya....

["Epidemiology","Global Health","HIV","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.303v2
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