Preprints (not yet peer-reviewed)

25 downloads
80 views

Background: Salvia officinalis (sage) is a native plant to the Mediterranean region and has been used for a long time in traditional medicine for various diseases. We investigated possible anti-diabetic, anti-inflammatory and anti-obesity effects of sage methanol...

["Diabetes and Endocrinology","Nutrition","Translational Medicine"]
doi:10.7287/peerj.preprints.3086v1
13 downloads
64 views

Objective: This study aims to compare the sensitivity of dual phase (non-contrast and arterial) versus single phase (arterial) CT for detection of hyper-functioning parathyroid glands in patients with primary hyperparathyroidism. Methods: The CT scans of thirty-two...

["Diabetes and Endocrinology","Radiology and Medical Imaging"]
doi:10.7287/peerj.preprints.3058v1
25 downloads
110 views

Background. The current study aims to explore the effects of advanced glycation end products (AGEs) on the microRNA (miRNA) expression profile in kidney tissues in a murine diabetic nephropathy (DN) model, and to investigate the possible underlying mechanisms....

["Genomics","Molecular Biology","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.3026v1
34 downloads
226 views

Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria. This animal species is surprisingly well adapted to free life in the World Ocean inhabiting tidal costal...

["Evolutionary Studies","Genomics","Molecular Biology","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.2945v1
51 downloads
177 views

Background. Currently, the number of obese people in the world has reached alarming proportions. During the expansion of adipose tissue, a number of functions such as activation and release of cytokines and hormones may be affected. This causes the body to take...

["Diabetes and Endocrinology","Nutrition"]
doi:10.7287/peerj.preprints.2535v1
141 downloads
244 views

Steroids play multiple roles in the regulation of development, physiology, reproduction, and behavior. Measuring circulating steroids is especially challenging since concentrations are extremely labile, responding to stressors within minutes. Matrices that integrate...

["Andrology","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.2069v2
84 downloads
397 views

Aim/hypothesis The aim of our study was to characterize the human salivary proteome and determine the changes in protein expression in 2 different stages of diabetic retinopathy with type-2 diabetes mellitus: (1) with non-proliferative diabetic retinopathy (NPDR)...

["Biochemistry","Diabetes and Endocrinology","Ophthalmology"]
doi:10.7287/peerj.preprints.1973v1
313 downloads
373 views

Purpose. Type 2 diabetes is the leading cause of end stage renal disease in the United States. Atherosclerotic renal artery stenosis is commonly observed in diabetic patients and impacts the rate of renal and cardiovascular disease progression. We hypothesized...

["Cardiology","Diabetes and Endocrinology","Nephrology","Pathology","Translational Medicine"]
doi:10.7287/peerj.preprints.1323v2
135 downloads
285 views

The growing number of wildlife endocrinology studies have greatly enhanced our understanding of comparative endocrinology, and have also generated extensive longitudinal data for a vast number of species. However, the extensive graphical analysis required for these...

["Biodiversity","Computational Biology","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.1546v1
150 downloads
194 views

Type 2 diabetes mellitus (T2DM) is a chronic and progressive disease that is strongly associated with the all-cause and cardiovascular mortality. The present study aimed to analyze the abundance and functionality of intrinsically disordered regions in several biomarkers...

["Biochemistry","Bioinformatics","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.1395v1
956 downloads
559 views

Whether obesity is a disease or a risk factor of chronic diseases including diabetes and fatty liver remains debating. We report here that a high-fat diet (HFD) alone or HFD and intramuscular injection of mice with a high dose (1.2 mg/kg) of lipopolysaccharide...

["Diabetes and Endocrinology","Pathology","Pharmacology","Metabolic Sciences"]
doi:10.7287/peerj.preprints.1229v1
172 downloads
309 views

The metabolic syndrome (MS) affects 21-53% of patients with chronic obstructive pulmonary disease (COPD) with a higher prevalence in the early stages of COPD, with results being highly variable between studies. MS may also correlate with disease characteristics....

["Diabetes and Endocrinology","Epidemiology","Internal Medicine","Respiratory Medicine"]
doi:10.7287/peerj.preprints.1022v1
337 downloads
405 views

INTRODUCTION: Diabetic retinopathy affects majority (70% to 90%) of diabetic patients, causes visual impairment which leads to severe psycho-social disruption in life. Our objective was to study the patients of diabetic retinopathy, co-relate between the types...

["Diabetes and Endocrinology","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.981v1
382 downloads
333 views

Diabetes mellitus (DM) affects 2-37% of patients with chronic obstructive pulmonary disease (COPD), with results being highly variable between studies. DM may also correlate with disease characteristics.The aim of this study was to examine the prevalence of DM...

["Diabetes and Endocrinology","Epidemiology","Internal Medicine","Respiratory Medicine"]
doi:10.7287/peerj.preprints.939v1
88 downloads
508 views

It is unclear whether the adipokine chemerin has pro- or anti-inflammatory properties, plays any role in the aetiology of obesity or type 2 diabetes, or whether agonists or antagonists of the chemerin receptor CMKLR1 have potential in the treatment of these diseases....

["Diabetes and Endocrinology","Pharmacology","Metabolic Sciences"]
doi:10.7287/peerj.preprints.643v1
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