Preprints (not yet peer-reviewed)

70 downloads
302 views

Motivation Nowadays, advances in technology has arisen in a huge amount of data in both biomedical research and healthcare systems. This growing amount of data gives rise to the need for new research methods and analysis techniques. Analysis of these data offers...

["Bioinformatics","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2186v1
44 downloads
285 views

MOTIVATION Alkaptonuria (AKU) is a rare and genetic disease which causes discoloration of bone (a process called ‘ochronosis’) and induces early-onset osteoarthritis. AKU data have not been organized yet and the disease has no approved biomarkers. The ability to...

["Bioinformatics","Computational Biology","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2174v1
149 downloads
475 views

In a recent paper, Beall, Hofer, and Schaller (2016) use observational time series data to test the hypothesis that the 2014 Ebola outbreak influenced the 2014 U.S. Federal Elections. They find substantial associations between online search volume for Ebola and...

["Anthropology","Evolutionary Studies","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2165v2
140 downloads
332 views

The potential of soils to naturally suppress inherent plant pathogens is an important ecosystem function. Usually, pathogen infection assays are used for estimating the suppressive potential of soils. In natural soils, however, co-occurring pathogens might simultaneously...

["Agricultural Science","Biodiversity","Microbiology","Plant Science","Statistics"]
doi:10.7287/peerj.preprints.2156v1
20 downloads
157 views

Hierarchical models are characterized by having N living states connected by N–1 rates of transfer. Demographic measures for such models can be calculated directly from counts of the number of persons in each state at two nearby points in time. Exploiting the ability...

["Public Health","Women's Health","Statistics"]
doi:10.7287/peerj.preprints.2128v1
99 downloads
409 views

Background. Feirana quadranus and Feirana taihangnica, two species of frogs inhabiting in waterbodies in the Qinling Mountains, China, are believed to be sister species that diverged 4.6 million years ago. In their sympatric area, morphological variations found...

["Evolutionary Studies","Molecular Biology","Taxonomy","Zoology","Statistics"]
doi:10.7287/peerj.preprints.2058v2
90 downloads
616 views

Genome-wide association studies (GWAS) have uncovered thousands of associations between genetic variants and diseases. Using the same datasets, prediction of disease risk can be attempted. Phase information is an important biological structure that has seldom been...

["Bioinformatics","Computational Biology","Genomics","Epidemiology","Statistics"]
doi:10.7287/peerj.preprints.2074v1
1,513 downloads
9,146 views

We present a simple mathematical technique that we call GRIM (Granularity-Related Inconsistency of Means) for verifying the summary statistics of published research reports in psychology. This technique evaluates whether the reported means of integer data such...

["Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2064v1
50 downloads
160 views

Background: Skinfold thickness (SFT) measurements are a reliable and feasible method for assessing body fat in children but their use and interpretation is hindered by the scarcity of reference values in representative populations of children. The objectives of...

["Epidemiology","Nutrition","Pediatrics","Public Health","Statistics"]
doi:10.7287/peerj.preprints.2053v1
65 downloads
246 views

Objective: The aim of this study was to use the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines to evaluate the quality of reporting of recent gastric cancer animal experiments. Materials and Methods: A literature search of studies was performed...

["Veterinary Medicine","Gastroenterology and Hepatology","Oncology","Translational Medicine","Statistics"]
doi:10.7287/peerj.preprints.2049v1
46 downloads
191 views

Background. In the early and late stages of cell reprogramming to induced pluripotent stem cells (iPSCs) ectopic expression of Oct4, Sox2, Klf4 and Myc (OSKM) aroused two peaks of transcriptional and epigenetic change respectively. However, it was relatively quiet...

["Bioinformatics","Cell Biology","Mathematical Biology","Molecular Biology","Statistics"]
doi:10.7287/peerj.preprints.1991v1
76 downloads
290 views

Background. Hand gestures play an important role in face-to-face communication. Although studies have shown that the mirror neuron system and the mentalizing system are involved in gesture comprehension, evidence of how the two systems are activated during gesture...

["Neuroscience","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.1975v1
440 downloads
350 views

Objectives: To develop a flexible software application that uses predictive analytics to enable emergency department (ED) decision-makers in virtually any environment to predict the effects of operational interventions and enhance continual process improvement...

["Emergency and Critical Care","Statistics"]
doi:10.7287/peerj.preprints.1891v2
39 downloads
247 views

Residual water is a critical parameter in assessing the quality of immunological veterinary medicinal products (IVMPs). In majority of the laboratories the Karl Fischer titration (KFT) is used for the determination of water content in IVMPs. However, the transfer...

["Veterinary Medicine","Statistics"]
doi:10.7287/peerj.preprints.1858v1
99 downloads
538 views

To statistically evaluate the performance of brain-computer interfaces (BCIs), researchers usually rely on null hypothesis significance testing (NHST), i.e. p-values. However, over-reliance on NHST is often identified as one of the causes of the recent reproducibility...

["Neuroscience","Statistics","Human-Computer Interaction"]
doi:10.7287/peerj.preprints.1828v1
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