Preprints (not yet peer-reviewed)

7 downloads
139 views

Pedigrees, though straightforward and versatile, lack the ability to tell us information about many individuals. Though numerical systems have been developed, there has yet to be a system that tells us the probabilities of a pedigree following certain inheritance...

["Bioinformatics","Genetics","Mathematical Biology","Statistics"]
doi:10.7287/peerj.preprints.2871v3
203 downloads
1,065 views

1. Stable isotope analysis is a widely used tool for the reconstruction and interpretation of animal diets and trophic relationships. Analytical tools have improved the robustness of inferring the relative contribution of different prey sources to an animal’s diet...

["Computational Biology","Ecology","Ecosystem Science","Zoology","Statistics"]
doi:10.7287/peerj.preprints.1950v2
20 downloads
123 views

A measure of statistical evidence should permit the sample size determination so that the probability M of obtaining (strong) misleading evidence can be held as low as desired. On this desideratum the p-value fails completely, as it leads either to an arbitrary...

["Bioinformatics","Epidemiology","Statistics"]
doi:10.7287/peerj.preprints.2869v1
29 downloads
102 views

Mutualistic communities play an important role in biodiversity preservation. They are modeled as bipartite networks and measurements of centrality and degree help to order species and their relative importance for network robustness. Identifying the most endangered...

["Ecology","Ecosystem Science","Statistics"]
doi:10.7287/peerj.preprints.2855v1
17 downloads
114 views

We studied the effect of linearization on the repeatability of the Tofts and reference region models (RRM) for Dynamic Contrast-Enhanced MRI (DCE MRI). We compared the repeatabilities of these two linearized models, the standard non-linear version, and semi-quantitative...

["Mathematical Biology","Radiology and Medical Imaging","Statistics"]
doi:10.7287/peerj.preprints.2824v1
37 downloads
104 views

The ecological niche concept has a revival interest under climate change, especially to study its impact on niche shift and/or conservatism. Here, we propose the Within Outlying Mean Indexes (WitOMI), which refines the Outlying Mean Index (OMI) analysis by using...

["Ecology","Statistics"]
doi:10.7287/peerj.preprints.2810v1
47 downloads
150 views

We present survey questions useful for describing agricultural seed systems. The questions are designed so that they can be used for standardized comparisons among seed systems, addressing both networks for seed movement and networks for the communication of information...

["Agricultural Science","Microbiology","Plant Science","Statistics","Coupled Natural and Human Systems"]
doi:10.7287/peerj.preprints.2806v1
9 downloads
93 views

Basic idea of science is reproducibility of phenomena and experiments. Reproducibility of data analyses and reports is becoming more and more important. It requires structured organization of data, augmented with enought metadata for future re-use of data. Our...

["Bioinformatics","Genomics","Plant Science","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2791v1
53 downloads
206 views

Objective: Trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might represent a novel therapeutic breakthrough. Various decellularized TM scaffolds were developed...

["Bioengineering","Ophthalmology","Statistics"]
doi:10.7287/peerj.preprints.2736v3
100 downloads
255 views

Background RNA sequencing (RNA-Seq) is a powerful technique for transcriptome profiling of the organisms that uses the capabilities of next-generation sequencing (NGS) technologies. Recent advances in NGS let to measure the expression levels of tens to thousands...

["Bioinformatics","Genomics","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2761v1
4,471 downloads
11,525 views

We present the initial results of a reanalysis of four articles from the Cornell Food and Brand Lab based on data collected from diners at an Italian restaurant buffet. On a first glance at these articles, we immediately noticed a number of apparent inconsistencies...

["Ethical Issues","Science Policy","Statistics"]
doi:10.7287/peerj.preprints.2748v1
56 downloads
213 views

Site-specific evolutionary rates can be estimated from codon sequences or from amino-acid sequences. For codon sequences, the most popular methods use some variation of the dN/dS ratio. For amino-acid sequences, one widely-used method is called Rate4Site, and it...

["Bioinformatics","Computational Biology","Evolutionary Studies","Statistics"]
doi:10.7287/peerj.preprints.2739v1
190 downloads
428 views

This study was conducted to investigate the theory of dual coding on remembering words, by testing whether concrete words are better recalled than abstract words. A total of 298 (from Asian ethnicity) participants took part in this study. The participants were...

["Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2719v1
82 downloads
408 views

Measurement of pupil size (pupillometry) has recently gained renewed interest from psychologists, but there is little agreement on how pupil-size data is best analyzed. Here we focus on one aspect of pupillometric analyses: baseline correction, that is, analyzing...

["Neuroscience","Ophthalmology","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2725v1
27 downloads
272 views

Marker gene sequencing of microbial communities has generated big datasets of microbial relative abundances varying across environmental conditions, sample sites and treatments. These data often come with putative phylogenies, providing unique opportunities to...

["Computational Biology","Ecology","Mathematical Biology","Microbiology","Statistics"]
doi:10.7287/peerj.preprints.2685v1
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