Preprints (not yet peer-reviewed)

Previous studies have used the zebrafish to investigate the biology of lens crystallin proteins and their roles in development and disease. However, little is known about zebrafish α-crystallin promoter function, how it compares to that of mammals, or whether mammalian...

["Developmental Biology","Molecular Biology","Neuroscience","Ophthalmology"]
doi:10.7287/peerj.preprints.2889v1

Background. The goals of this study were (1) to present the set of data evaluating running biomechanics (kinematics and kinetics), including data on running habits, demographics, and levels of muscle strength and flexibility made available at Figshare (DOI: 10.6084/m9.figshare.4543435);...

["Bioengineering","Neuroscience","Kinesiology","Computational Science"]
doi:10.7287/peerj.preprints.2888v1
9 downloads
132 views

This article describes a public data set with the three-dimensional kinematics of the whole body and the ground reaction forces (with a dual force platform setup) of subjects standing still for 60 s in different conditions, in which the vision and the standing...

["Bioengineering","Neuroscience","Kinesiology"]
doi:10.7287/peerj.preprints.2865v1
16 downloads
150 views

Background: Bilingualism is a universal phenomenon. Study of bilingual brain has provided evidence to probable advantageous outcomes of early second language learning and brain structural correlates to these outcomes. Preservation of cognitive function with aging...

["Neuroscience","Radiology and Medical Imaging"]
doi:10.7287/peerj.preprints.2853v1
168 downloads
780 views

Synapsida, the clade including therapsids and thus also mammals, is one of the two major branches of amniotes. Organismal design, with modularity as a concept, offers insights into the evolution of therapsids, a group that experienced profound anatomical transformations...

["Developmental Biology","Evolutionary Studies","Neuroscience","Paleontology","Anatomy and Physiology"]
doi:10.7287/peerj.preprints.2313v2
14 downloads
92 views

It is now widely accepted that oligomers consisting of Aβ peptide are the cytotoxic species contributing mostly to the development of Alzheimer’s disease. Aβ peptide production results from the specific proteolytic processing of the amyloid precursor protein (APP)....

["Biophysics","Biotechnology","Cell Biology","Molecular Biology","Neuroscience"]
doi:10.7287/peerj.preprints.2804v1
17 downloads
108 views

Background. Fibroblast growth factors (FGFs) and their receptors (FGFRs) are involved in the development and function of multiple organs and organ systems, including the central nervous system (CNS). FGF signaling via FGFR1, one of the three FGFRs expressed in...

["Cell Biology","Developmental Biology","Neuroscience"]
doi:10.7287/peerj.preprints.2729v1
82 downloads
408 views

Measurement of pupil size (pupillometry) has recently gained renewed interest from psychologists, but there is little agreement on how pupil-size data is best analyzed. Here we focus on one aspect of pupillometric analyses: baseline correction, that is, analyzing...

["Neuroscience","Ophthalmology","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2725v1
117 downloads
310 views

A major goal of systems neuroscience is to understand how the brain represents information, and how those representations are used to drive behavior. Even though genetic model organisms like Drosophila grant unprecedented experimental access to the nervous system...

["Animal Behavior","Computational Biology","Neuroscience"]
doi:10.7287/peerj.preprints.2720v1
32 downloads
179 views

Background. Bax Inhibitor-1 (BI-1), an integral transmembrane protein, acts as a suppressor of Bax-induced apoptosis through regulation of endoplasmic reticulum (ER) stress-induced cell death. The gene is highly conserved being found in a diverse range of organisms...

["Cell Biology","Genetics","Neuroscience"]
doi:10.7287/peerj.preprints.2548v1
61 downloads
176 views

Background. Firefighting requires tremendous cognitive demands including assessing emergency scenes, executing critical decisions, and situational awareness of their surroundings. The aim of this study was to determine the effects of differing rates of increasing...

["Neuroscience","Cognitive Disorders","Kinesiology"]
doi:10.7287/peerj.preprints.2524v1
30 downloads
178 views

Major risk factors for neurodegenerative diseases share brain hypometabolism as one common outcome. In turn, many neurodegenerative pathologies result in brain hypometabolism; both epilepsy and Alzheimer's disease are characterised by disruptions in glucose metabolism....

["Neuroscience","Metabolic Sciences"]
doi:10.7287/peerj.preprints.2521v1
46 downloads
156 views

The purpose of the study was to investigate the characteristics of the attentional network in college table tennis athletes. A total of 65 college students categorized as table tennis athlete group or non-athlete group participated in the study. All participants...

["Neuroscience","Kinesiology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.2508v1
144 downloads
325 views

The main function of brains is to generate adaptive behavior. Far from being the stereotypical, robot-like insect, the fruit fly Drosophila exhibits astounding flexibility and chooses different courses of actions even under identical external circumstances. Due...

["Animal Behavior","Genetics","Neuroscience","Zoology"]
doi:10.7287/peerj.preprints.2491v1
86 downloads
206 views

As such, video games are enjoyed most when the level and speed of the game match the players’ skills. An optimal balance between challenges and skills triggers the subjective experience of “flow”, a focused motivation leading to a feeling of spontaneous joy. Here...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.2482v1
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