Preprints (not yet peer-reviewed)

35 downloads
94 views

A scientific theory or hypothesis is presented, in which mineral particles may play a pivotal role in the prion disease transmissible spongiform encephalopathy (TSE), and possibly also in other protein-misfolding diseases. Montmorillonite clay (Mte) and other minerals...

["Cell Biology","Molecular Biology","Infectious Diseases","Neurology"]
doi:10.7287/peerj.preprints.2982v1
58 downloads
229 views

Whole genome sequencing is opening the door to novel insights into the population structure and evolutionary history of poorly known species. In organisms with large genomes, which includes most amphibians, whole-genome sequencing is excessively challenging and...

["Bioinformatics","Evolutionary Studies","Genomics","Molecular Biology","Zoology"]
doi:10.7287/peerj.preprints.2980v1
32 downloads
131 views

The use of multiple sampling areas in landscape genetic analysis has been recognized as a useful way to generalize the patterns of environmental effects on gene flow. It allows reducing the variability of inference, accounting for multiple scales and locations...

["Entomology","Environmental Sciences","Molecular Biology"]
doi:10.7287/peerj.preprints.2968v1
10 downloads
104 views

Movement in proteins requires energy. To this end, natural selection has selected phosphate as the principal energy currency in cells. On the other hand, depicting the state of transcription could come in the form of epigenetic markers, which are modifications...

["Biochemistry","Cell Biology","Computational Biology","Genetics","Molecular Biology"]
doi:10.7287/peerj.preprints.2966v1
9 downloads
98 views

Stenotrophomonas maltophilia is an antibiotic resistant Gram-negative pathogen, which is associated with hospital-acquired infection. The genome encodes a protein highly related to the Ax21 protein of Xanthomonas oryzae pv. oryzae that is implicated in interactions...

["Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.2955v1
39 downloads
149 views

Elevated sea surface temperatures (SSTs) are linked to an increase in the frequency and severity of bleaching events due to temperatures exceeding corals’ upper thermal limits. The temperatures at which a breakdown of the coral-Symbiodinium endosymbiosis (coral...

["Genetics","Marine Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.2949v1
63 downloads
227 views

Characteristics of late maturity in fruits are good agronomic traits for extending the harvest period and marketing time. However, underlying molecular basis of the late-maturing mechanism in fruit is largely unknown. In this study, RNA sequencing (RNA-Seq) technology...

["Agricultural Science","Biotechnology","Molecular Biology","Plant Science"]
doi:10.7287/peerj.preprints.2744v2
27 downloads
180 views

Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria. This animal species is surprisingly well adapted to free life in the World Ocean inhabiting tidal costal...

["Evolutionary Studies","Genomics","Molecular Biology","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.2945v1
6 downloads
115 views

Background: Tibetans have lived at high altitudes for thousands of years, and they have a unique composition of physiological traits that enable them to tolerate this hypoxic environment. However, the genetic basis of these traits is still unknown. As a sensitive...

["Molecular Biology","Hematology"]
doi:10.7287/peerj.preprints.2929v1
44 downloads
155 views

In the past decades, novel pharmaceutical compounds have been produced by a wide diverse groups of marine bacteria. These marine bacteria are potential reservoirs for antimicrobial products. In this study, we investigated 40 soil samples collected from the Great...

["Biodiversity","Genomics","Marine Biology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.2910v1
25 downloads
265 views

Background. The diatom Phaeodactylum tricornutum is a model photosynthetic organism. Functional genomic work in this organism has established a variety of genetic tools including RNA interference (RNAi). RNAi is a post-transcriptional regulatory process that can...

["Biotechnology","Genetics","Marine Biology","Molecular Biology","Synthetic Biology"]
doi:10.7287/peerj.preprints.2907v1
19 downloads
230 views

12R-LOX over-expression has been reported in various pathologies such as psoriasis, proliferative dermatitis as well as pulmonary obstructive diseases indicating that this enzyme plays significant role in pathogenesis of inflammatory diseases. 12R-LOX, therefore,...

["Biochemistry","Molecular Biology"]
doi:10.7287/peerj.preprints.2906v1
30 downloads
151 views

Background. Members of the genus Bifidobacterium are abundant in the feces of babies during the exclusively-milk-diet period of life. Bifidobacterium longum is reported to be a common member of the infant fecal microbiota. However, B. longum is composed of three...

["Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.2899v1
13 downloads
237 views

Previous studies have used the zebrafish to investigate the biology of lens crystallin proteins and their roles in development and disease. However, little is known about zebrafish α-crystallin promoter function, how it compares to that of mammals, or whether mammalian...

["Developmental Biology","Molecular Biology","Neuroscience","Ophthalmology"]
doi:10.7287/peerj.preprints.2889v1
208 downloads
1,067 views

1) DNA metabarcoding holds great promise for the assessment of macroinvertebrates in stream ecosystems. However, few large-scale studies have compared the performance of DNA metabarcoding with that of routine morphological identification. 2) We performed metabarcoding...

["Biodiversity","Environmental Sciences","Molecular Biology","Zoology","Science Policy"]
doi:10.7287/peerj.preprints.2759v3
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