Preprints (not yet peer-reviewed)

17 downloads
74 views

Arbutin (p-hydroxyphenyl-β-D-glucopyranoside), a well-known tyrosinase inhibitor, has been widely used as a cosmetic whitening agent. Although its natural role is to scavenge free radicals within cells, it has also exhibited useful activities for the treatment...

["Animal Behavior","Biochemistry","Molecular Biology"]
doi:10.7287/peerj.preprints.3405v1
17 downloads
100 views

Background: Haemophilus parasuis is a common porcine respiratory disease that causes high rates of morbidity and mortality in farmed swine. We performed a molecular characterization of antimicrobial resistance genes harbored by H. parasuis from pig farms in China....

["Microbiology","Molecular Biology","Epidemiology","Statistics"]
doi:10.7287/peerj.preprints.3386v1
28 downloads
107 views

Specific regulation and activation of focal adhesion kinase (FAK) are thought to be important for focal adhesion formation, and activation of Rho-kinase has been suggested to play a role in determining the effects of FAK on the formation of stress fibers and focal...

["Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3297v1
38 downloads
127 views

Corals rely on a symbiosis with dinoflagellate algae (Symbiodinium spp.) to thrive in nutrient poor tropical oceans. However, the coral-algal symbiosis can break down during bleaching events, potentially leading to coral death. While genome-wide expression studies...

["Genetics","Marine Biology","Molecular Biology","Zoology"]
doi:10.7287/peerj.preprints.3283v1
148 downloads
652 views

DNA metabarcoding provides species composition data for entire communities, yet information on intraspecific diversity is usually lost during data analysis. The capacity to infer intraspecific genetic diversity within whole communities would, however, represent...

["Biogeography","Bioinformatics","Molecular Biology","Freshwater Biology"]
doi:10.7287/peerj.preprints.3269v1
86 downloads
180 views

Although most reef-building corals live near the upper threshold of their thermotolerance, some scleractinians are resilient to temperature increases. For instance, Pocillopora acuta specimens from an upwelling habitat in Southern Taiwan survived a 9-month experimental...

["Cell Biology","Environmental Sciences","Marine Biology","Molecular Biology","Climate Change Biology"]
doi:10.7287/peerj.preprints.3252v1
13 downloads
82 views

Microfluidic cell culture chambers have enabled the isolation, culture and growth of various species of microorganisms and human cells. However, based on elastomers such as poly(dimethyl siloxane) (PDMS), these culture devices are not readily amenable to imaging...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3245v1
44 downloads
229 views

The gastro-intestinal (GI) microbiota of abalone contains a highly complex bacterial assemblage playing an essential role in the overall health of these gastropods. The gut bacterial communities characterized so far reveal considerable interspecific variability,...

["Bioinformatics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.3233v1
24 downloads
339 views

Epigenetic research focuses on understanding non-inheritable factors influencing gene regulation and covers various cellular mechanisms such as DNA methylation, histone modification, miRNA function and transcription factor binding sites. Recent advances in high-throughput...

["Bioinformatics","Computational Biology","Genetics","Molecular Biology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.3224v1
66 downloads
128 views

Single cell studies increasing reveal myriad cellular subtypes beyond those postulated or observed through optical and fluorescence microscopy as well as DNA sequencing studies. While gene sequencing at the single cell level offer a path towards illuminating, in...

["Biochemistry","Biotechnology","Cell Biology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.3193v1
121 downloads
205 views

The USA National Center for Biotechnology Information (NCBI) is one of the world’s most important sources of biological information. NCBI databases like PubMed and GenBank contain millions of records describing bibliographic, genetic, genomic, and medical data....

["Bioinformatics","Genetics","Genomics","Molecular Biology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.3179v2
104 downloads
341 views

DNA analysis of predator feces using high-throughput amplicon sequencing (HTS) enhances our understanding of predator-prey interactions. However, conclusions drawn from this technique are constrained by biases that occur in multiple steps of the HTS workflow. To...

["Bioinformatics","Ecology","Entomology","Molecular Biology","Zoology"]
doi:10.7287/peerj.preprints.3184v1
49 downloads
176 views

Members of the anaerobic gut fungi (AGF) reside in rumen, hindgut, and feces of ruminant and non-ruminant herbivorous mammals and reptilian herbivores. No protocols for gene insertion, deletion, silencing, or mutation are currently available for the AGF, rendering...

["Molecular Biology","Mycology"]
doi:10.7287/peerj.preprints.3177v1
34 downloads
175 views

A growing number of T2/S-RNases are being discovered in plant genomes. Members of this protein family have a variety of known functions, but the vast majority are still uncharacterized. We present data and analyses of phylogenetic relationships among T2/S-RNases,...

["Evolutionary Studies","Genetics","Genomics","Molecular Biology","Plant Science"]
doi:10.7287/peerj.preprints.3171v1
18 downloads
129 views

Particle bombardment is a powerful and relatively easy method for transient expression of genes of interest in plant cells, especially those that are recalcitrant to other transformation methods. This method has facilitated numerous analyses of subcellular localization...

["Cell Biology","Molecular Biology","Plant Science"]
doi:10.7287/peerj.preprints.3164v1
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