Preprints (not yet peer-reviewed)

64 downloads
327 views

We explore environmentally-induced tumors in the context of the ongoing conflict between long-evolved cancer control mechanisms and the central flaw of multicellularity, using a number of convergent necessary conditions statistical models based on the Data Rate...

["Evolutionary Studies","Mathematical Biology","Oncology","Public Health"]
doi:10.7287/peerj.preprints.1709v1
558 downloads
315 views

Background: Dengue is one of the most important vector-borne diseases, nearly 400000 reported cases in South East Asia and more than 2000 fatalities annually. The first of dengue vaccine called Dengvaxia by the French company, Sanofi Pasteur, was recently approved...

["Computational Biology","Mathematical Biology","Infectious Diseases"]
doi:10.7287/peerj.preprints.1694v1
70 downloads
215 views

Cluster analysis is one of the most commonly used methods in palaeoecological studies, particularly in studies investigating biogeographic patterns. Although a number of different clustering methods are widely used, the approach and underlying assumptions of many...

["Biogeography","Computational Biology","Ecology","Mathematical Biology","Paleontology"]
doi:10.7287/peerj.preprints.1693v1
64 downloads
198 views

Counteracting the worldwide trend of coral reef degeneration is a major challenge for the scientific community. A crucial management approach to minimizing stress effects on healthy reefs and helping the recovery of disturbed reefs is reef protection. However,...

["Aquaculture, Fisheries and Fish Science","Conservation Biology","Ecology","Mathematical Biology"]
doi:10.7287/peerj.preprints.1664v1
168 downloads
114 views

Length of hospital stay (LOS) is of primary importance in health services research because it is directly related to health care management and cost of health care. In some epidemiological settings the actual length of stay is not directly observed but it is known...

["Mathematical Biology","Epidemiology","Infectious Diseases","Public Health","Statistics"]
doi:10.7287/peerj.preprints.1663v1
41 downloads
150 views

The conservation and management of wild populations and ecosystems almost always involves making decisions in the face of uncertainty and risk. The application of science to the ecological decision-making process was something that the late Professor Daniel Goodman...

["Conservation Biology","Ecology","Mathematical Biology","Science Policy","Statistics"]
doi:10.7287/peerj.preprints.1583v1
65 downloads
194 views

An informal review of the history of new quantitative methods in environmental science, including environmental risk assessment, shows about a 10- to 20-year lag in wide acceptance of such methods by management agencies. To reduce that lag time as innovative methods...

["Aquaculture, Fisheries and Fish Science","Conservation Biology","Environmental Sciences","Marine Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.1569v1
57 downloads
138 views

Under models of isolation-by-distance, population structure is determined by the probability of identity-by-descent between pairs of genes according to the geographic distance between them. Well established analytical results indicate that the relationship between...

["Computational Biology","Evolutionary Studies","Genetics","Mathematical Biology"]
doi:10.7287/peerj.preprints.1545v1
502 downloads
267 views

Background. Usain Bolt holds the current world record for a 100-m run, 9.58 s, and has been described as the best human sprinter in history. However, this raises questions concerning the maximum human running speed. Can the world’s fastest men become faster still?...

["Bioengineering","Computational Biology","Mathematical Biology","Anatomy and Physiology","Kinesiology"]
doi:10.7287/peerj.preprints.1484v1
560 downloads
512 views

Mathematical models are frequently used to assess the impact of control interventions for Chlamydia trachomatis and other sexually transmitted infections (STIs). Modeling approaches that stratify the population by the number of sex partners often assume the transmission...

["Computational Biology","Mathematical Biology","Epidemiology","Infectious Diseases","Statistics"]
doi:10.7287/peerj.preprints.940v2
146 downloads
371 views

The sexually transmitted bacterium Neisseria gonorrhoeae has developed resistance to all antibiotic classes that have been used for treatment and strains resistant to multiple antibiotic classes have evolved. In many countries, there is only one antibiotic remaining...

["Computational Biology","Evolutionary Studies","Mathematical Biology","Epidemiology","Infectious Diseases"]
doi:10.7287/peerj.preprints.1449v1
100 downloads
209 views

The conserved nature of sleep in Drosophila has allowed the fruit fly to emerge in the last decade as a powerful model organism in which to study sleep. Recent sleep studies in Drosophila have focused on the discovery and characterization of hyposomnolent mutants....

["Animal Behavior","Entomology","Mathematical Biology","Statistics"]
doi:10.7287/peerj.preprints.1408v1
117 downloads
264 views

Colony Collapse Disorder has become a global problem for beekeepers and for the crops which depend on bee polination. Multiple factors are known to increase the risk of colony colapse, and the ectoparasitic mite Varroa destructor that parasitizes honey bees (Apis...

["Ecology","Mathematical Biology"]
doi:10.7287/peerj.preprints.1396v1
120 downloads
224 views

Ricker’s stock recruitment model is widely used to describe the spawner-offspring relationship for fishes. After model fitting, the spawning stock size that produces the maximum sustainable yield (SMSY), and the harvest corresponding to it (UMSY), are two of the...

["Ecology","Mathematical Biology"]
doi:10.7287/peerj.preprints.1394v1
147 downloads
363 views

In biological mass spectrometry, crude instrumental data need to be converted into meaningful theoretical models. Several data processing and data evaluation steps are required to come to the final results. These operations are often difficult to reproduce, because...

["Bioinformatics","Biophysics","Computational Biology","Mathematical Biology","Statistics"]
doi:10.7287/peerj.preprints.1359v1
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