Preprints (not yet peer-reviewed)

7 downloads
91 views

Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria. This animal species is surprisingly well adapted to free life in the World Ocean inhabiting tidal costal...

["Evolutionary Studies","Genomics","Molecular Biology","Diabetes and Endocrinology"]
doi:10.7287/peerj.preprints.2945v1
11 downloads
106 views

Assay for Transposase Accessible Chromatin (ATAC-seq) is an open chromatin profiling assay that is adapted to interrogate chromatin accessibility from small cell numbers. ATAC-seq surmounted a major technical barrier and enabled epigenome profiling of clinical...

["Bioinformatics","Computational Biology","Genomics"]
doi:10.7287/peerj.preprints.2942v1
11 downloads
215 views

The characteristic ground colour and banding patterns on shells of the land snail Cepaea nemoralis form a classic study system for genetics and adaptation. We use RNAseq analysis to identify candidate genes underlying this polymorphism. We sequenced cDNA from the...

["Evolutionary Studies","Genetics","Genomics"]
doi:10.7287/peerj.preprints.2928v1
8 downloads
94 views

Background. The microbiota in the small intestine relies on their capacity to rapidly import and ferment available carbohydrates to survive in a complex and highly competitive ecosystem. Understanding how these communities function requires elucidating the role...

["Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2918v1
9 downloads
76 views

Chinese fir (Cunninghamia lanceolata (Lamb.) Hook) is an excellent fast-growing timber species and has significant value in the forestry industry. In order to increase the nitrogen and phosphorus absorption and utilization in Chinese fir, shared differentially...

["Agricultural Science","Biotechnology","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.2916v1
20 downloads
123 views

High sensitivity methods such as next generation sequencing and polymerase chain reaction (PCR) are adversely impacted by organismal and DNA contaminants. Current methods for detecting contaminants in microbial materials (genomic DNA and cultures) are not sensitive...

["Bioinformatics","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2913v1
17 downloads
159 views

With the emergence of Next Generation Sequencing, major advances were made with regard to identifying viruses in natural environments. However, bioinformatical research on viruses is still limited because of the low amounts of viral DNA that can be obtained for...

["Biodiversity","Genomics","Microbiology","Virology"]
doi:10.7287/peerj.preprints.2912v1
28 downloads
117 views

In the past decades, novel pharmaceutical compounds have been produced by a wide diverse groups of marine bacteria. These marine bacteria are potential reservoirs for antimicrobial products. In this study, we investigated 40 soil samples collected from the Great...

["Biodiversity","Genomics","Marine Biology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.2910v1
135 downloads
1,143 views

As the generation and use of genomic datasets is becoming increasingly common in all areas of biology, the need for resources to collate, analyse and present data from one or more genome projects is becoming more pressing. The Ensembl platform is a powerful tool...

["Bioinformatics","Genomics"]
doi:10.7287/peerj.preprints.2401v2
29 downloads
110 views

Platycladus orientalis in China has a lifespan of one to several thousands of years. The long lifespans of trees have attracted interest in aging at the molecular level. There is little information on how the global process is controlled. In this study, the MDA...

["Genomics","Plant Science"]
doi:10.7287/peerj.preprints.2866v1
61 downloads
295 views

Metatranscriptomics and metaproteomics make it possible to measure gene expression in microbial communities. So far these approaches were mostly used to get a general overview of the dominant metabolism and physiologies of community members. Recently, environmental...

["Bioinformatics","Ecology","Environmental Sciences","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2846v1
24 downloads
137 views

Microorganism is an important part of ecosystems; it is very sensitive to environmental change. In order to study the effects of sound on organisms, it’s meaningful to study mechanism of microbial exposure to sound. In our previous experiments, the effects of different...

["Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2821v1
54 downloads
134 views

Aerobic anoxygenic phototrophic bacteria (AAPB) containing bacteriochlorophyll a (BChl a) are photoheterotrophic prokaryotes that are a widely distributed functional bacterial group due to their obligately aerobic and facultative photoheterotrophic abilities. Here,...

["Ecology","Environmental Sciences","Genomics","Marine Biology","Microbiology"]
doi:10.7287/peerj.preprints.2820v1
10 downloads
110 views

Basic idea of science is reproducibility of phenomena and experiments. Reproducibility of data analyses and reports is becoming more and more important. It requires structured organization of data, augmented with enought metadata for future re-use of data. Our...

["Bioinformatics","Genomics","Plant Science","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2791v1
777 downloads
579 views

Divergence of treatment responses to chemotherapy exists across patients (often with unknown underlying mechanisms), with some patients exhibiting worsened outcome upon treatment. Genomic approaches (such as microarray profiling and whole genome sequencing) hold...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v6
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