Preprints (not yet peer-reviewed)

15 downloads
130 views

We investigated the structure and properties of PCL10 nanofiber, PCL5/PCL10 core-shell type nanofibers, as well as PCL5/PCLAg nanofibres prepared by electrospinning. For the production of the fibre variants, a 5-10% solution of polycaprolactone (Mw = 70000-90000),...

["Bioengineering","Biotechnology","Synthetic Biology"]
doi:10.7287/peerj.preprints.2971v1
10 downloads
99 views

Most biological processes within a cell are carried out by protein-protein interaction (PPI) networks, or so called interactomics. Therefore, identification of PPIs is crucial to elucidating protein functions and further understanding of various cellular biological...

["Bioinformatics","Biotechnology","Computational Biology"]
doi:10.7287/peerj.preprints.2964v1
64 downloads
229 views

Characteristics of late maturity in fruits are good agronomic traits for extending the harvest period and marketing time. However, underlying molecular basis of the late-maturing mechanism in fruit is largely unknown. In this study, RNA sequencing (RNA-Seq) technology...

["Agricultural Science","Biotechnology","Molecular Biology","Plant Science"]
doi:10.7287/peerj.preprints.2744v2
15 downloads
110 views

Chinese fir (Cunninghamia lanceolata (Lamb.) Hook) is an excellent fast-growing timber species and has significant value in the forestry industry. In order to increase the nitrogen and phosphorus absorption and utilization in Chinese fir, shared differentially...

["Agricultural Science","Biotechnology","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.2916v1
25 downloads
266 views

Background. The diatom Phaeodactylum tricornutum is a model photosynthetic organism. Functional genomic work in this organism has established a variety of genetic tools including RNA interference (RNAi). RNAi is a post-transcriptional regulatory process that can...

["Biotechnology","Genetics","Marine Biology","Molecular Biology","Synthetic Biology"]
doi:10.7287/peerj.preprints.2907v1
382 downloads
802 views

Microbes, while living in close proximity in biofilms, may in other cases not be closely localized in the environment. In the latter case, their interactions and communications are dependent on myriad factors such as existence of direct connections (e.g., web of...

["Biochemistry","Biotechnology","Cell Biology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.349v6
66 downloads
130 views

Ribulose-1,5-bisphosphate carboxylase/oxygense (RuBisCO) is present in plants and autotrophic organisms like microalgae. The aim of this study was to perform an in silico evaluation of RuBisCo protein in microalgae and cyanobacteria as potential precursors of bioactive...

["Bioinformatics","Biotechnology"]
doi:10.7287/peerj.preprints.2875v1
22 downloads
146 views

It is now widely accepted that oligomers consisting of Aβ peptide are the cytotoxic species contributing mostly to the development of Alzheimer’s disease. Aβ peptide production results from the specific proteolytic processing of the amyloid precursor protein (APP)....

["Biophysics","Biotechnology","Cell Biology","Molecular Biology","Neuroscience"]
doi:10.7287/peerj.preprints.2804v1
52 downloads
119 views

CodonGenie, freely available from http://codon.synbiochem.co.uk, is a simple web application for designing ambiguous codons to support protein mutagenesis applications. Ambiguous codons are derived from specific heterogeneous nucleotide mixtures, which create sequence...

["Bioengineering","Bioinformatics","Biotechnology","Computational Biology","Synthetic Biology"]
doi:10.7287/peerj.preprints.2797v1
60 downloads
348 views

Introduction 2nd generation sequencing or better known as next-generation sequencing (NGS) represents a cutting-edge technology in life sciences and current foundation for unravelling nucleotide sequences. Since advent of first platforms in 2005 the number of different...

["Bioinformatics","Biotechnology","Genomics","Molecular Biology"]
doi:10.7287/peerj.preprints.2771v1
33 downloads
213 views

The filamentous fungus Rhizopus delemar naturally accumulates relatively high amounts of fumarate. Although the culture conditions that increase fumarate yields are well established, the network underlying the accumulation of fumarate is not yet fully understood....

["Biochemistry","Bioinformatics","Biotechnology","Microbiology"]
doi:10.7287/peerj.preprints.2742v1
30 downloads
107 views

Natural product libraries are important tools for drug discovery. However, until now, there has not been a system to allow projections of the potential number of hits from creating these libraries. The objective of this study was to develop a stochastic model system...

["Biodiversity","Biotechnology","Microbiology","Drugs and Devices","Computational Science"]
doi:10.7287/peerj.preprints.2734v1
10 downloads
115 views

The biological activities of quinoxalone, a novel small molecular substance isolated from the broth of the myxobacterium Stigmatella eracta WXNXJ-B, was investigated. This study was designed to determine the anti-proliferative, apoptotic property of quinoxalone,...

["Biotechnology","Microbiology","Pharmacology"]
doi:10.7287/peerj.preprints.2703v1
99 downloads
166 views

Synthetic biology is often misunderstood as creation of artificial life or new biology using principles different from those of extant organisms around us. But, fundamentally, the field is about engineering biology in a more efficient and effective way, and endowing...

["Biochemistry","Bioengineering","Biotechnology","Computational Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.2634v1
137 downloads
121 views

Advancement of modern biotechnology has wide impact on various industries. Modern biotechnology in the past has gone unregulated but the responsible use of biotechnology is the main focus worldwide. The most important living modified organisms (LMOs) regulatory...

["Biodiversity","Biotechnology","Legal Issues"]
doi:10.7287/peerj.preprints.2569v1
What is a PeerJ Preprint?

A PeerJ Preprint is a draft of an article, abstract, or poster that has not yet been peer-reviewed for formal publication. Submit a draft, incomplete, or final version of your work for free.

Submissions today can be approved by Editorial Staff and online in 24 hours.

Establish precedent. Solicit feedback. Publish updates.

Top subject areas - Preprints

Top subject areas - People

View all subject areas