Preprints (not yet peer-reviewed)

81 downloads
125 views

We propose a new hypothesis about the physical-chemical mechanisms of nerve conduction in myelinated nerves, tending to bridge the theoretical gap existing to date between the basic neuronal activity and its adaptation to myelination. All the considerations imply...

["Biochemistry","Neuroscience","Neurology"]
doi:10.7287/peerj.preprints.3409v1
11 downloads
57 views

Arbutin (p-hydroxyphenyl-β-D-glucopyranoside), a well-known tyrosinase inhibitor, has been widely used as a cosmetic whitening agent. Although its natural role is to scavenge free radicals within cells, it has also exhibited useful activities for the treatment...

["Animal Behavior","Biochemistry","Molecular Biology"]
doi:10.7287/peerj.preprints.3405v1
15 downloads
84 views

While biochemistry evidently affects the growth rate of cells, many biochemists routinely ignore population variation, just like population geneticists usually ignore causal details of biochemistry that underpin a change in growth rate caused by a mutation. A true...

["Biochemistry","Cell Biology","Computational Biology","Oncology","Computational Science"]
doi:10.7287/peerj.preprints.3371v1
22 downloads
125 views

Background: Oxidative stress plays an important role in the pathogenesis of heart diseases. Antioxidants such as palm tocotrienol-rich fraction (TRF) can reduce oxidative stress, hence preventing and reducing the risk of heart disease. This study was aimed to determine...

["Biochemistry","Nutrition"]
doi:10.7287/peerj.preprints.3333v1
19 downloads
110 views

Transglutaminases (TGases) are a class of enzyme widely spread in nature, and observed in plants, microorganisms, vertebrates and invertebrates. This enzyme catalyzes post-translational protein modification, by acyl transfer reactions, deamidation and crosslinking...

["Biochemistry","Bioinformatics"]
doi:10.7287/peerj.preprints.3320v1
17 downloads
156 views

Quality disciplines have been widely used for decades in industrial and business fields. It is only in recent times, however, that Quality management and approaches have received proper attention in life science. The development, optimization, validation and dissemination...

["Biochemistry","Cell Biology","Developmental Biology","Ethical Issues","Science Policy"]
doi:10.7287/peerj.preprints.3316v1
225 downloads
2,671 views

The classification of Cannabis varieties has been increasingly discussed in the past years, particularly in the wake of emerging legal markets, with implications for intellectual property development, marketing and improvement of the scientific understanding of...

["Agricultural Science","Biochemistry","Biodiversity","Plant Science","Taxonomy"]
doi:10.7287/peerj.preprints.3307v1
24 downloads
79 views

Scale transcends multiple levels of biological and physical organization, and is the critical factor that determines success of any scientific investigation. Specifically, the scale at which a question is posed plays a crucial role in influencing the type of experiments...

["Biochemistry","Bioengineering","Biophysics","Biotechnology","Cell Biology"]
doi:10.7287/peerj.preprints.3261v1
13 downloads
82 views

Microfluidic cell culture chambers have enabled the isolation, culture and growth of various species of microorganisms and human cells. However, based on elastomers such as poly(dimethyl siloxane) (PDMS), these culture devices are not readily amenable to imaging...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3245v1
8 downloads
123 views

Co-existence of microbes in a community is the de facto state of microbial lifestyle in almost all niches on Earth. Thus, microbes live with other microbial species in close proximity, and evolution has selected for specific methods of communication between microbes...

["Biochemistry","Biodiversity","Cell Biology","Ecology","Microbiology"]
doi:10.7287/peerj.preprints.3239v1
14 downloads
231 views

Contemporary proteins can be traced back to a basic set of a few thousand domain prototypes. The origin of these domain prototypes, however, remains poorly understood. We have proposed that they arose from an ancestral set of peptides, which acted as cofactors...

["Biochemistry","Bioinformatics","Evolutionary Studies"]
doi:10.7287/peerj.preprints.3234v1
66 downloads
128 views

Single cell studies increasing reveal myriad cellular subtypes beyond those postulated or observed through optical and fluorescence microscopy as well as DNA sequencing studies. While gene sequencing at the single cell level offer a path towards illuminating, in...

["Biochemistry","Biotechnology","Cell Biology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.3193v1
127 downloads
189 views

Background. Carrot is a multi-nutritional food source. It is an important root vegetable, rich in natural bioactive compounds with health-promoting properties, such as antioxidants that have anti-carcinogenic properties. Aim. This review summarises the occurrences...

["Agricultural Science","Biochemistry","Food Science and Technology","Plant Science","Nutrition"]
doi:10.7287/peerj.preprints.3187v1
289 downloads
758 views

Microbes for environmental research should be cultured in growth media with characteristics (e.g., pH, ionic strength, and ionic composition) as close to their original habitat as possible. Additionally, the medium should also enable high cell density to be obtained,...

["Biochemistry","Bioengineering","Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.1406v6
351 downloads
5,343 views

In 1961, the NIH began to circulate biological preprints in a forgotten experiment called the Information Exchange Groups (IEGs). This system eventually attracted over 3600 participants and saw the production of over 2,500 different documents, but by 1967 it was...

["Biochemistry","Science Policy"]
doi:10.7287/peerj.preprints.3174v1
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