Peer-reviewed Articles - Computer sci

58 downloads
577 views

Genome sequencing is rapidly being adopted in reference labs and hospitals for bacterial outbreak investigation and diagnostics where time is critical. Seven gene multi-locus sequence typing is a standard tool for broadly classifying samples into sequence types...

["Bioinformatics","Microbiology","Epidemiology"]
doi:10.7717/peerj.5233
111 downloads
543 views

Background Minimal change disease (MCD) is a kind of nephrotic syndrome (NS). In this study, we aimed to establish a mathematical diagnostic model based on biological parameters to classify MCD. Methods A total of 798 NS patients were divided into MCD group and...

["Bioinformatics","Epidemiology","Nephrology"]
doi:10.7717/peerj.4237
3 citations
344 downloads
2,415 views

Background As next generation sequence technology has advanced, there have been parallel advances in genome-scale analysis programs for determining evolutionary relationships as proxies for epidemiological relationship in public health. Most new programs skip traditional...

["Bioinformatics","Evolutionary Studies","Food Science and Technology","Genomics","Epidemiology"]
doi:10.7717/peerj.3893
1 citation
186 downloads
901 views

Background C-X-C chemokine ligand 12 (CXCL12) has important implications in breast cancer (BC) pathogenesis. It is selectively expressed on B and T lymphocytes and is involved in hematopoiesis, thymocyte trafficking, stem cell motility, neovascularization, and...

["Bioinformatics","Computational Biology","Genetics","Epidemiology"]
doi:10.7717/peerj.3822
3 citations
409 downloads
2,289 views

In this study we developed a genome-based method for detecting Staphylococcus aureus subtypes from metagenome shotgun sequence data. We used a binomial mixture model and the coverage counts at >100,000 known S. aureus SNP (single nucleotide polymorphism) sites...

["Bioinformatics","Genomics","Microbiology","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.2571

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