Peer-reviewed Articles - Medicine

1 citation
127 downloads
575 views

Candidemia and other forms of invasive fungal infections caused by Candida glabrata and to a lesser extent Saccharomyces cerevisiae are a serious health problem, especially if their steadily rising resistance to the limited range of antifungal drugs is taken into...

["Microbiology","Drugs and Devices","Infectious Diseases","Public Health"]
doi:10.7717/peerj.4999
2 citations
143 downloads
756 views

Many infectious diseases disproportionately affect people in the developing world. Cryptococcal meningitis is one of the most common mycoses in HIV-AIDS patients, with the highest burden of disease in sub-Saharan Africa. Current best treatment regimens still result...

["Microbiology","Mycology","Drugs and Devices","Infectious Diseases"]
doi:10.7717/peerj.4761
2 citations
392 downloads
2,152 views

Introduction The repurposing of non-antibiotic drugs as adjuvant antibiotics may help break antimicrobial resistance (AMR). Statins are commonly prescribed worldwide to lower cholesterol. They also possess qualities of AMR “breakers”, namely direct antibacterial...

["Microbiology","Drugs and Devices","Global Health","Infectious Diseases","Pharmacology"]
doi:10.7717/peerj.3952
283 downloads
1,132 views

Background Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid...

["Microbiology","Drugs and Devices","Infectious Diseases"]
doi:10.7717/peerj.3887
3 citations
420 downloads
1,629 views

Rhodomyrtone, a natural antimicrobial compound, displays potent activity against many Gram-positive pathogenic bacteria, comparable to last-defence antibiotics including vancomycin and daptomycin. Our previous studies pointed towards effects of rhodomyrtone on...

["Biochemistry","Computational Biology","Microbiology","Drugs and Devices","Infectious Diseases"]
doi:10.7717/peerj.2962
2 citations
433 downloads
1,412 views

Klebsiella pneumoniae is responsible for numerous infections caused in hospitals, leading to mortality and morbidity. It has been evolving as a multi-drug resistant pathogen, acquiring multiple resistances such as such as horizontal gene transfer, transposon-mediated...

["Microbiology","Molecular Biology","Drugs and Devices","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.2896
13 citations
991 downloads
6,464 views

Viral RNA helicases are involved in duplex unwinding during the RNA replication of the virus. It is suggested that these helicases represent very promising antiviral targets. Viruses of the flaviviridae family are the causative agents of many common and devastating...

["Bioinformatics","Computational Biology","Evolutionary Studies","Drugs and Devices","Infectious Diseases"]
doi:10.7717/peerj.74

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