Peer-reviewed Articles

51 downloads
231 views

Since the development of human-induced pluripotent stem cells (hiPSCs), various types of hiPSC-derived cells have been established for regenerative medicine and drug development. Neural stem/progenitor cells (NSPCs) derived from hiPSCs (hiPSC-NSPCs) have shown...

["Neuroscience","Toxicology"]
doi:10.7717/peerj.4187
49 downloads
337 views

Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a high-production volume organophosphate flame retardant widely used within the United States. Within zebrafish, initiation of TDCIPP exposure at 0.75 h post-fertilization (hpf) results in genome-wide alterations...

["Developmental Biology","Toxicology","Ecotoxicology"]
doi:10.7717/peerj.4156
108 downloads
1,721 views

Background Pesticidal RNAs that silence critical gene function have great potential in pest management, but the benefits of this technology must be weighed against non-target organism risks. Methods Published studies that developed pesticidal double stranded RNAs...

["Biotechnology","Ecology","Entomology","Toxicology","Ecotoxicology"]
doi:10.7717/peerj.4131
55 downloads
251 views

The mechanistic target of rapamycin (mTOR) and ryanodine receptor (RyR) signaling pathways regulate fundamental processes of neurodevelopment, and genetic mutations within these pathways have been linked to neurodevelopmental disorders. While previous studies have...

["Developmental Biology","Neuroscience","Toxicology"]
doi:10.7717/peerj.4106
62 downloads
255 views

The objectives of this experiment were to determine the effects of graded dietary lead (Pb) concentrations on body weight and Pb concentrations in blood, hair, soft tissues, and urine from pigs and to generate equations for estimating daily Pb intake. Sixteen barrows...

["Agricultural Science","Toxicology","Nutrition","Ecotoxicology"]
doi:10.7717/peerj.3936
271 downloads
363 views

Background Litchi stink-bug, Tessaratoma papillosa Drury (Hemiptera: Tessaratomidae), is one of the most widespread and destructive pest species on Litchi chinensis Sonn and Dimocarpus longan Lour in Southern China. Inappropriate use of chemical pesticides has...

["Agricultural Science","Entomology","Microbiology","Mycology","Toxicology"]
doi:10.7717/peerj.3888
109 downloads
471 views

Cadmium (Cd) is one of the most toxic heavy metals and is difficult to be removed from contaminated soil and water. Italian ryegrass (Lolium multiflorum), as an energy crop, exhibits a valuable potential to develop Cd polluted sites due to its use as a biofuel...

["Plant Science","Toxicology","Biosphere Interactions","Ecotoxicology","Natural Resource Management"]
doi:10.7717/peerj.3621
122 downloads
506 views

Background High mobility group box 1 (HMGB1) is a well-known damage-related alarmin that participates in cellular inflammatory responses. However, the mechanisms leading to HMGB1 release in inflammatory conditions and the therapeutic agents that could prevent it...

["Biotechnology","Toxicology","Drugs and Devices","Evidence Based Medicine","Pharmacology"]
doi:10.7717/peerj.3808
1 citation
108 downloads
340 views

Objective To determine the profile of 14 polybrominated diphenyl ethers (PBDEs) and 23 polychlorinated biphenyls (PCBs) in serum of domestic canines and whether this was predictive of thyroid hormone status. Samples Serum samples were collected from 51 client-owned...

["Environmental Sciences","Toxicology","Veterinary Medicine","Ecotoxicology"]
doi:10.7717/peerj.3780
61 downloads
401 views

Discarded vehicle tire casings are an important artificial habitat for the developmental stages of numerous vector mosquitoes. Discarded vehicle tires degrade under ultraviolet light and leach numerous soluble metals (e.g., barium, cadmium, zinc) and organic substances...

["Ecology","Entomology","Toxicology"]
doi:10.7717/peerj.3756
73 downloads
473 views

Background Heterocyclic aromatic amines (HAA) are environmental and food contaminants that are potentially carcinogenic for humans. 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) is one of the most abundant HAA formed in cooked meat. MeIQx is metabolized...

["Computational Biology","Toxicology"]
doi:10.7717/peerj.3703
62 downloads
567 views

The growing use of carbon nanotubes (CNTs) in industrial and consumer products raises important questions about their environmental fate and impact on prokaryotes. In the environment, CNTs are exposed to a variety of conditions (e.g., UV light) that could lead...

["Microbiology","Toxicology"]
doi:10.7717/peerj.3721
324 downloads
1,028 views

Worldwide occurrences of honey bee colony losses have raised concerns about bee health and the sustainability of pollination-dependent crops. While multiple causal factors have been identified, seed coating with insecticides of the neonicotinoid family has been...

["Agricultural Science","Ecology","Entomology","Toxicology","Ecotoxicology"]
doi:10.7717/peerj.3670
173 downloads
505 views

This study investigated whether zeolites of different size (Y30 (nano-sized) and H-Beta(OH)-III (forming large aggregates/agglomerates composed of 50 nm small primary particles)) exerted acute toxicity on larvae of the non-biting midge, Chironomus riparius, and...

["Environmental Sciences","Toxicology"]
doi:10.7717/peerj.3525
1 citation
257 downloads
1,337 views

There is widespread concern regarding the effects of agro-chemical exposure on bee health, of which neonicotinoids, systemic insecticides detected in the pollen and nectar of both crops and wildflowers, have been the most strongly debated. The majority of studies...

["Ecology","Entomology","Environmental Sciences","Toxicology","Zoology"]
doi:10.7717/peerj.3417

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