Peer-reviewed Articles

25 downloads
231 views

Tartrazine is a synthetic organic azo dye widely used in food and pharmaceutical products. The current study aimed to evaluate the possible adverse effect of this coloring food additive on renal and hepatic structures and functions. Also, the genotoxic potential...

["Biochemistry","Molecular Biology","Zoology","Histology"]
doi:10.7717/peerj.3041
21 downloads
344 views

Quantifying the genetic diversity in natural populations is crucial to address ecological and evolutionary questions. Despite recent advances in whole-genome sequencing, microsatellite markers have remained one of the most powerful tools for a myriad of population...

["Biodiversity","Evolutionary Studies","Genetics","Marine Biology","Molecular Biology"]
doi:10.7717/peerj.2936
56 downloads
436 views

Background Colorectal cancer (CRC) is one of the leading cancers worldwide. Several studies have performed microarray data analyses for cancer classification and prognostic analyses. Microarray assays also enable the identification of gene signatures for molecular...

["Bioinformatics","Mathematical Biology","Molecular Biology","Oncology","Statistics"]
doi:10.7717/peerj.3003
65 downloads
324 views

We estimated the genetic diversity of 50 Jatropha curcas samples from the Costa Rican germplasm bank using 18 EST-SSR, one G-SSR and nrDNA-ITS markers. We also evaluated the phylogenetic relationships among samples using nuclear ribosomal ITS markers. Non-toxicity...

["Biodiversity","Molecular Biology","Plant Science"]
doi:10.7717/peerj.2931
42 downloads
249 views

Synaptotagmin I (Syt I) is most abundant in the brain and is involved in multiple cellular processes. Its two C2 domains, C2A and C2B, are the main functional regions. Our present study employed a pull-down combined with proteomic strategy to identify the C2 domain-interacting...

["Biochemistry","Molecular Biology","Neuroscience"]
doi:10.7717/peerj.2973
53 downloads
286 views

Macrobrachium rosenbergii nodavirus (MrNv) poses a major threat to the prawn industry. Currently, no effective vaccine and treatment are available to prevent the spread of MrNv. Its infection mechanism and localisation in a host cell are also not well characterised....

["Biotechnology","Cell Biology","Microbiology","Molecular Biology","Virology"]
doi:10.7717/peerj.2947
56 downloads
160 views

Background This study investigates orbitally-forced range dynamics at a regional scale by exploring the evolutionary history of Nymania capensis (Meliaceae) across the deeply incised landscapes of the subescarpment coastal lowlands of South Africa; a region that...

["Biogeography","Conservation Biology","Molecular Biology","Plant Science"]
doi:10.7717/peerj.2965
58 downloads
159 views

Root hairs are unicellular elongations of certain rhizodermal cells that improve the uptake of sparingly soluble and immobile soil nutrients. Among different Arabidopsis thaliana genotypes, root hair density, length and the local acclimation to low inorganic phosphate...

["Agricultural Science","Cell Biology","Genetics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.2891
80 downloads
428 views

The development of the brain is sex-dimorphic, and as a result so are many neurological disorders. One approach for studying sex-dimorphic brain development is to measure gene expression in biological samples using RT-qPCR. However, the accuracy and consistency...

["Developmental Biology","Genomics","Molecular Biology","Neuroscience"]
doi:10.7717/peerj.2909
101 downloads
360 views

Klebsiella pneumoniae is responsible for numerous infections caused in hospitals, leading to mortality and morbidity. It has been evolving as a multi-drug resistant pathogen, acquiring multiple resistances such as such as horizontal gene transfer, transposon-mediated...

["Microbiology","Molecular Biology","Drugs and Devices","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.2896
46 downloads
309 views

Intracellular calcium ion (Ca2+) signaling is heavily involved in development, as illustrated by the use of a number of Ca2+ indicators. However, continuous Ca2+ patterns during morphogenesis have not yet been studied using fluorescence resonance energy transfer...

["Developmental Biology","Molecular Biology"]
doi:10.7717/peerj.2894
70 downloads
739 views

Background The wood frog, Rana sylvatica, tolerates freezing as a means of winter survival. Freezing is considered to be an ischemic/anoxic event in which oxygen delivery is significantly impaired. In addition, cellular dehydration occurs during freezing because...

["Biochemistry","Cell Biology","Genetics","Molecular Biology","Zoology"]
doi:10.7717/peerj.2797
61 downloads
438 views

Type I restriction-modification enzymes are multisubunit, multifunctional molecular machines that recognize specific DNA target sequences, and their multisubunit organization underlies their multifunctionality. EcoR124I is the archetype of Type I restriction-modification...

["Biochemistry","Biophysics","Computational Biology","Molecular Biology"]
doi:10.7717/peerj.2887
53 downloads
388 views

An adult Buteo was found dead as a road-kill south of Sacramento, California, and was thought to represent the first state record of the eastern Red-shouldered Hawk (B. lineatus lineatus;). It is now a specimen in the Museum of Wildlife and Fisheries Biology (WFB...

["Molecular Biology","Taxonomy","Zoology"]
doi:10.7717/peerj.2850
73 downloads
355 views

Fish color patterns are among the most diverse phenotypic traits found in the animal kingdom. Understanding the molecular and cellular mechanisms that control in chromatophore distribution and pigmentation underlying this diversity is a major goal in developmental...

["Aquaculture, Fisheries and Fish Science","Biodiversity","Evolutionary Studies","Molecular Biology","Zoology"]
doi:10.7717/peerj.2843

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