Peer-reviewed Articles

72 downloads
795 views

The dodo (Raphus cucullatus) might be the most enigmatic bird of all times. It is, therefore, highly remarkable that no consensus has yet been reached on its body mass; previous scientific estimates of its mass vary by more than 100%. Until now, the vast amount...

["Mathematical Biology","Paleontology"]
doi:10.7717/peerj.4110
34 downloads
411 views

A recurrent question within oncology drug development is predicting phase III outcome for a new treatment using early clinical data. One approach to tackle this problem has been to derive metrics from mathematical models that describe tumour size dynamics termed...

["Mathematical Biology","Clinical Trials","Oncology","Pharmacology","Statistics"]
doi:10.7717/peerj.4111
145 downloads
1,146 views

Background In this paper, we propose a new method, named the intervals’ method, to analyse data from finite element models in a comparative multivariate framework. As a case study, several armadillo mandibles are analysed, showing that the proposed method is useful...

["Animal Behavior","Mathematical Biology","Paleontology"]
doi:10.7717/peerj.3793
76 downloads
381 views

Objective The objective of this study is to conduct a systematic review of multi-scale HIV immunoepidemiological models to improve our understanding of the synergistic impact between the HIV viral-immune dynamics at the individual level and HIV transmission dynamics...

["Computational Biology","Mathematical Biology","Epidemiology","HIV","Immunology"]
doi:10.7717/peerj.3877
90 downloads
572 views

Extinction models vary in the information they require, the simplest considering the rate of certain sightings only. More complicated methods include uncertain sightings and allow for variation in the reliability of uncertain sightings. Generally extinction models...

["Conservation Biology","Ecology","Mathematical Biology"]
doi:10.7717/peerj.3663
1 citation
1,328 downloads
24,775 views

The running ability of Tyrannosaurus rex has been intensively studied due to its relevance to interpretations of feeding behaviour and the biomechanics of scaling in giant predatory dinosaurs. Different studies using differing methodologies have produced a very...

["Mathematical Biology","Paleontology","Zoology"]
doi:10.7717/peerj.3420
65 downloads
400 views

Objective Osteoarthritis (OA) is a disease characterized by degeneration of joint cartilage. It is associated with pain and disability and is the result of either age and activity related joint wear or an injury. Non-invasive treatment options are scarce and prevention...

["Mathematical Biology","Orthopedics"]
doi:10.7717/peerj.3468
110 downloads
511 views

Empirical and mechanistic modeling indicate that pathogens transmitted via aerially dispersed inoculum follow a power law, resulting in dispersive epidemic waves. The spread parameter (b) of the power law model, which is an indicator of the distance of the epidemic...

["Ecology","Mathematical Biology","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.3465
112 downloads
553 views

The purpose of this study was to verify a theoretical model of parents’ responses to difficulties they experienced with their child. The model presents relationships between seven variables: (a) discrepancy between parental goal and the child’s current level of...

["Mathematical Biology","Pediatrics","Psychiatry and Psychology","Statistics"]
doi:10.7717/peerj.3384
97 downloads
424 views

Recruitment is a key demographic process for population persistence. This paper focuses on barnacle (Semibalanus balanoides) recruitment. In rocky intertidal habitats from the Gulf of St. Lawrence coast of Nova Scotia (Canada), ice scour is common during the winter....

["Animal Behavior","Ecology","Marine Biology","Mathematical Biology","Zoology"]
doi:10.7717/peerj.3444
113 downloads
776 views

The changes of protein expression that are monitored in proteomic experiments are a type of biological transformation that also involves changes in chemical composition. Accompanying the myriad molecular-level interactions that underlie any proteomic transformation,...

["Biochemistry","Mathematical Biology","Oncology"]
doi:10.7717/peerj.3421
141 downloads
604 views

Coral reefs are dynamic systems whose composition is highly influenced by unpredictable biotic and abiotic factors. Understanding the spatial scale at which long-term predictions of reef composition can be made will be crucial for guiding conservation efforts....

["Ecology","Marine Biology","Mathematical Biology"]
doi:10.7717/peerj.3290
2 citations
251 downloads
870 views

The Ramachandran plot is important to structural biology as it describes a peptide backbone in the context of its dominant degrees of freedom—the backbone dihedral angles φ and ψ (Ramachandran, Ramakrishnan & Sasisekharan, 1963). Since its introduction, the Ramachandran...

["Computational Biology","Mathematical Biology","Computational Science"]
doi:10.7717/peerj.3327
1 citation
129 downloads
549 views

Background Pyropia haitanensis thalli, which are made of a single layer of polygonal cells, are a perfect model for studying the morphogenesis of multi-celled organisms because their cell proliferation process is an excellent example of the manner in which cells...

["Cell Biology","Mathematical Biology"]
doi:10.7717/peerj.3314
3 citations
286 downloads
1,762 views

Given the rapid population decline and recent petition for listing of the monarch butterfly (Danaus plexippus L.) under the Endangered Species Act, an accurate estimate of the Eastern, migratory population size is needed. Because of difficulty in counting individual...

["Conservation Biology","Ecology","Entomology","Mathematical Biology"]
doi:10.7717/peerj.3221

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