Peer-reviewed Articles

329 downloads
350 views

Background Antimicrobial use in livestock production is an important contemporary issue, which is of public interest worldwide. Antimicrobials are not freely available to Austrian farmers and can only be administered to livestock by veterinarians, or by farmers...

["Agricultural Science","Veterinary Medicine","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.4072
38 downloads
244 views

Background Dengue disease is a leading cause of illness and death in the tropics and subtropics. Most severe cases occur among patients secondarily infected with a different dengue virus (DENV) serotype compared with that from the first infection, resulting in...

["Biotechnology","Molecular Biology","Virology","Infectious Diseases"]
doi:10.7717/peerj.4021
37 downloads
215 views

Respiratory syncytial virus (RSV) causes acute lower respiratory tract infection in infants and young children worldwide. To investigate the RSV burden in Thailand over four consecutive years (January 2012 to December 2015), we screened 3,306 samples obtained from...

["Virology","Infectious Diseases"]
doi:10.7717/peerj.3970
53 downloads
644 views

Households are an important location for the transmission of communicable diseases. Social contact between household members is typically more frequent, of greater intensity, and is more likely to involve people of different age groups than contact occurring in...

["Anthropology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3958
117 downloads
689 views

Introduction The repurposing of non-antibiotic drugs as adjuvant antibiotics may help break antimicrobial resistance (AMR). Statins are commonly prescribed worldwide to lower cholesterol. They also possess qualities of AMR “breakers”, namely direct antibacterial...

["Microbiology","Drugs and Devices","Global Health","Infectious Diseases","Pharmacology"]
doi:10.7717/peerj.3952
89 downloads
354 views

Background The interaction between influenza virus and the host response to infection clearly plays an important role in determining the outcome of infection. While much is known on the participation of inflammation on the pathogenesis of severe A (H1N1) pandemic...

["Global Health","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3915
56 downloads
234 views

Background Parkinson’s disease (PD) is a disorder characterized by dopaminergic neuron programmed cell death. The etiology of PD remains uncertain—some cases are due to selected genes associated with familial heredity, others are due to environmental exposure to...

["Microbiology","Neuroscience","Infectious Diseases"]
doi:10.7717/peerj.3823
147 downloads
415 views

Human papillomavirus (HPV) is the leading cause of cervical cancer. Urine-based HPV testing offers a simple and non-invasive method because of its increasing acceptance. A total of 164 pairs of cervical swab and urine samples from Thai women who underwent cervical...

["Virology","Infectious Diseases","Oncology","Women\u2019s Health"]
doi:10.7717/peerj.3910
83 downloads
255 views

Background Astragalus polysaccharide (APS) has immunomodulatory activities on porcine peripheral blood mononuclear cells. The immunomodulatory effects of APS on porcine endothelial cells (ECs) expose to classical swine fever virus (CSFV) remain unknown. Methods...

["Cell Biology","Veterinary Medicine","Infectious Diseases","Internal Medicine"]
doi:10.7717/peerj.3862
91 downloads
296 views

Background Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid...

["Microbiology","Drugs and Devices","Infectious Diseases"]
doi:10.7717/peerj.3887
149 downloads
544 views

Background Dengue viral infection is an acute infection that has the potential to have severe complications as its major sequela. Currently, there is no routine laboratory biomarker with which to predict the severity of dengue infection or monitor the effectiveness...

["Microbiology","Virology","Epidemiology","Immunology","Infectious Diseases"]
doi:10.7717/peerj.3589
78 downloads
520 views

Background Indigenous populations of the circumpolar Arctic are considered to be endemically infected (>2% prevalence) with hepatitis B virus (HBV), with subgenotype B5 (formerly B6) unique to these populations. The distinctive properties of HBV/B5, including high...

["Computational Biology","Evolutionary Studies","Virology","Infectious Diseases"]
doi:10.7717/peerj.3757
105 downloads
858 views

Background We aimed to determine the prevalence of vaginal colonization by Gardnerella vaginalis and of bacterial vaginosis (BV) in Portuguese pregnant women, and to identify risk factors for BV and G. vaginalis colonization in pregnancy. Methods A cross-sectional...

["Epidemiology","Gynecology and Obstetrics","Infectious Diseases","Women\u2019s Health"]
doi:10.7717/peerj.3750
177 downloads
597 views

In the swine industry, porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease which causes heavy economic losses worldwide. Effective prevention and disease control is an important issue. In this study, we described the construction...

["Veterinary Medicine","Virology","Infectious Diseases"]
doi:10.7717/peerj.3514
91 downloads
635 views

The major virulence factor of the pneumococcus, and target for conjugate vaccines, is the polysaccharide capsule, which is usually encoded by the highly variable cps locus. Serotype 37 is an unusual pneumococcal type in which the single β-glucosyltransferase gene...

["Bioinformatics","Genomics","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3571

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