Peer-reviewed Articles

17 downloads
90 views

Background Malaria elimination campaigns are planned or active in many countries. The effects of malaria elimination on immune responses such as antigen-specific IFN- γ responses are not well characterized. Methods IFN- γ responses to the P. falciparum antigens...

["Immunology","Infectious Diseases"]
doi:10.7717/peerj.2855
31 downloads
199 views

The emergence and spread of drug-resistance during treatment of many infectious diseases continue to degrade our ability to control and mitigate infection outcomes using therapeutic measures. While the coverage and efficacy of treatment remain key factors in the...

["Mathematical Biology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2817
51 downloads
178 views

Background Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment,...

["Microbiology","Infectious Diseases","Public Health","Metabolic Sciences"]
doi:10.7717/peerj.2833
99 downloads
363 views

G1P[8] rotaviruses are responsible for the majority of human rotavirus infections worldwide. The effect of universal mass vaccination with rotavirus vaccines on circulating G1P[8] rotaviruses is still poorly understood. Therefore we analyzed the complete genomes...

["Virology","Gastroenterology and Hepatology","Infectious Diseases"]
doi:10.7717/peerj.2733
117 downloads
205 views

Melioidosis, an infection caused by the facultative intracellular pathogen Burkholderia pseudomallei, has been classified as an emerging disease with the number of patients steadily increasing at an alarming rate. B. pseudomalleipossess various virulence determinants...

["Bioinformatics","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.2532
52 downloads
235 views

Tuberculosis is considered a leading cause of death worldwide. More than 95% of cases and deaths occur in low- and middle-income countries. In resource-limited countries, hospitals often lack adequate facilities to manage and isolate patients with infectious tuberculosis...

["Microbiology","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7717/peerj.2795
57 downloads
150 views

Background Daldinia eschscholtzii is a filamentous wood-inhabiting endophyte commonly found in woody plants. Here, we report the identification and characterization of nine D. eschscholtzii isolates from skin scrapings, nail clippings, and blood. Methods The nine...

["Mycology","Infectious Diseases","Pathology"]
doi:10.7717/peerj.2637
70 downloads
233 views

Many pathogenic mycobacteria are known to cause severe disease in humans and animals. M. avium subspecies paratuberculosis (Map) is the causative agent of Johne’s disease—a chronic wasting disease affecting ruminants such as cattle and sheep, responsible for significant...

["Genomics","Microbiology","Veterinary Medicine","Infectious Diseases"]
doi:10.7717/peerj.2793
69 downloads
340 views

Streptococcus pneumoniae is a pathogen that causes serious invasive infections, such as septicemia, meningitis and pneumonia in addition to mild upper respiratory tract infections. Protection from pneumococcal diseases is thought to be mediated mainly by serotype-specific...

["Immunology","Infectious Diseases"]
doi:10.7717/peerj.2737
114 downloads
1,301 views

One of the newest and strongest members of intercellular communicators, the Extracellular vesicles (EVs) and their enclosed RNAs; Extracellular RNAs (exRNAs) have been acknowledged as putative biomarkers and therapeutic targets for various diseases. Although a...

["Bioinformatics","Computational Biology","Infectious Diseases"]
doi:10.7717/peerj.2693
73 downloads
2,665 views

In 2013 approximately 37,000 people were living with HIV in Ecuador (prevalence 0.4%), representing a generalized epidemic where most new infections arise from sexual interactions in the general population. Studies that examine attitudes towards people living with...

["Global Health","Health Policy","HIV","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2726
84 downloads
345 views

Much is known regarding the antibiotic susceptibility of planktonic cultures of Mycobacterium tuberculosis, the bacterium responsible for the lung disease tuberculosis (TB). As planktonically-grown M. tuberculosis are unlikely to be entirely representative of the...

["Microbiology","Infectious Diseases"]
doi:10.7717/peerj.2717
133 downloads
593 views

In the mid-1980s, the largest epidemic of anthrax of the last 200 years was documented in a little known series of studies by Davies in The Central African Journal of Medicine. This epidemic involved thousands of cattle and 10,738 human cases with 200 fatalities...

["Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2686
55 downloads
249 views

This study compares and evaluates the prediction of hepatitis in Guangxi Province, China by using back propagation neural networks based genetic algorithm (BPNN-GA), generalized regression neural networks (GRNN), and wavelet neural networks (WNN). In order to compare...

["Epidemiology","Hematology","Infectious Diseases","Computational Science"]
doi:10.7717/peerj.2684
57 downloads
315 views

The spread of infectious diseases can be impacted by human behavior, and behavioral decisions often depend implicitly on a planning horizon—the time in the future over which options are weighed. We investigate the effects of planning horizons on epidemic dynamics....

["Mathematical Biology","Epidemiology","Infectious Diseases","Public Health","Computational Science"]
doi:10.7717/peerj.2678

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