Peer-reviewed Articles

67 downloads
388 views

Phytochemicals produced by plants, including at flowers, function in protection against plant diseases, and have a long history of use against trypanosomatid infection. Floral nectar and pollen, the sole food sources for many species of insect pollinators, contain...

["Ecology","Entomology","Parasitology","Plant Science","Infectious Diseases"]
doi:10.7717/peerj.3297
43 downloads
187 views

Tuberculosis is one of the world’s deadliest infectious disease with 1.5 millions deaths annually. It is imperative to discover novel compounds with potent activity against M. tuberculosis. In this study, susceptibilities of M. smegmatis to the octahedral ruthenium(II)...

["Biochemistry","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3252
58 downloads
257 views

Background The enzymatic degradation of quorums sensing (QS) molecules (called quorum quenching, QQ) has been considered as a promising anti-virulence therapy to treat biofilm-related infections and combat antibiotic resistance. The recently-discovered QQ enzyme...

["Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3251
59 downloads
485 views

Mayaro virus (MAYV) is an emergent sylvatic alphavirus in South America, related to sporadic outbreaks of a chikungunya-like human febrile illness accompanied by severe arthralgia. Despite its high potential for urban emergence, MAYV is still an obscure virus with...

["Biochemistry","Microbiology","Virology","Infectious Diseases"]
doi:10.7717/peerj.3245
41 downloads
274 views

Streptococcus pyogenes group A Streptococcus (GAS) is the most common cause of bacterial throat infections, and can cause mild to severe skin and soft tissue infections, including impetigo, erysipelas, necrotizing fasciitis, as well as systemic and fatal infections...

["Bioinformatics","Genomics","Microbiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3226
46 downloads
246 views

Efflux pump inhibitors are of great interest since their use as adjuvants of bacterial chemotherapy can increase the intracellular concentrations of the antibiotics and assist in the battle against the rising of antibiotic-resistant bacteria. In this work, we have...

["Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3168
78 downloads
399 views

Background Staphylococci are commensals of the mucosal surface and skin of humans and animals, but have been implicated in infections such as otitis externa, pyoderma, urinary tract infections and post-surgical complications. Laboratory records provide useful information...

["Veterinary Medicine","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.3198
124 downloads
706 views

Contemporary patterns of land use and global climate change are modifying regional pools of parasite host species. The impact of host community changes on human disease risk, however, is difficult to assess due to a lack of information about zoonotic parasite host...

["Biogeography","Ecology","Entomology","Parasitology","Infectious Diseases"]
doi:10.7717/peerj.3152
83 downloads
243 views

Background The diagnostic values of interferon-gamma release assays (IGRA) in tuberculosis (TB) vary a lot with different site of infections, with especially higher sensitivities in chronic forms of TB such as tuberculosis of the lymph node. We conducted a meta-analysis...

["Evidence Based Medicine","Infectious Diseases"]
doi:10.7717/peerj.3136
43 downloads
296 views

Background With the possible implications of global warming, the effect of temperature on the dynamics of malaria vectors in Africa has become a subject of increasing interest. Information from the field is, however, relatively sparse. We describe the effect of...

["Ecology","Entomology","Epidemiology","Global Health","Infectious Diseases"]
doi:10.7717/peerj.3099
100 downloads
616 views

Background The primary aim of the study reported here was to determine the effectiveness of utilizing local spatial variations in environmental data to uncover the statistical relationships between West Nile Virus (WNV) risk and environmental factors. Because least...

["Biogeography","Environmental Sciences","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3070
148 downloads
488 views

Background Zika virus (ZIKV) transmission has been reported in 67 countries/territories in the Oceania region and the Americas since 2015, prompting the World Health Organization (WHO) to declare ZIKV as a Public Health Emergency of International Concern in February...

["Mathematical Biology","Virology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3015
49 downloads
287 views

Background This study evaluates two procedures for typing of Streptococcus agalactiae (group B streptococci; GBS) isolates, using retrospective typing data from the period 2010 to 2014 with a commercial latex agglutination test (latex test) and the Lancefield precipitation...

["Microbiology","Epidemiology","Infectious Diseases","Internal Medicine","Pediatrics"]
doi:10.7717/peerj.3105
179 downloads
857 views

Zika virus is a newly emergent mosquito-borne flavivirus that has caused recent large outbreaks in the new world, leading to dramatic increases in serious disease pathology including Guillain-Barre syndrome, newborn microcephaly, and infant brain damage. Although...

["Entomology","Virology","Global Health","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3096
69 downloads
329 views

Background Dengue is a global human public health threat, causing severe morbidity and mortality. The occurrence of sequential infection by more than one serotype of dengue virus (DENV) is a major contributing factor for the induction of Dengue Hemorrhagic Fever...

["Molecular Biology","Virology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2970

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