Peer-reviewed Articles

60 downloads
255 views

Background Dengue viral infection is an acute infection that has the potential to have severe complications as its major sequela. Currently, there is no routine laboratory biomarker with which to predict the severity of dengue infection or monitor the effectiveness...

["Microbiology","Virology","Epidemiology","Immunology","Infectious Diseases"]
doi:10.7717/peerj.3589
49 downloads
332 views

Background Indigenous populations of the circumpolar Arctic are considered to be endemically infected (>2% prevalence) with hepatitis B virus (HBV), with subgenotype B5 (formerly B6) unique to these populations. The distinctive properties of HBV/B5, including high...

["Computational Biology","Evolutionary Studies","Virology","Infectious Diseases"]
doi:10.7717/peerj.3757
51 downloads
656 views

Background We aimed to determine the prevalence of vaginal colonization by Gardnerella vaginalis and of bacterial vaginosis (BV) in Portuguese pregnant women, and to identify risk factors for BV and G. vaginalis colonization in pregnancy. Methods A cross-sectional...

["Epidemiology","Gynecology and Obstetrics","Infectious Diseases","Women\u2019s Health"]
doi:10.7717/peerj.3750
114 downloads
434 views

In the swine industry, porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease which causes heavy economic losses worldwide. Effective prevention and disease control is an important issue. In this study, we described the construction...

["Veterinary Medicine","Virology","Infectious Diseases"]
doi:10.7717/peerj.3514
64 downloads
525 views

The major virulence factor of the pneumococcus, and target for conjugate vaccines, is the polysaccharide capsule, which is usually encoded by the highly variable cps locus. Serotype 37 is an unusual pneumococcal type in which the single β-glucosyltransferase gene...

["Bioinformatics","Genomics","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3571
106 downloads
615 views

Objective The aim of our study was to identify barriers and enablers to implementation of the Xpert MTB/RIF test within Mongolia’s National Tuberculosis Program. Methods Twenty-foursemi-structured interviews were conducted between June and September 2015 with laboratory...

["Infectious Diseases","Public Health"]
doi:10.7717/peerj.3567
91 downloads
327 views

Background Amoebiasis is the third most common parasitic cause of morbidity and mortality, particularly in countries with poor hygienic settings. There exists an ambiguity in the diagnosis of amoebiasis, and hence there arises a necessity for a better diagnostic...

["Biochemistry","Bioinformatics","Parasitology","Infectious Diseases"]
doi:10.7717/peerj.3160
77 downloads
447 views

Background The microbiome of built environment surfaces is impacted by the presence of humans. In this study, we tested the hypothesis that analysis of surface swabs from clinic toilet/bathroom yields results correlated with sexually transmitted infection (STI)...

["Microbiology","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.3487
109 downloads
386 views

Background Pharyngitis is an inflammatory condition of the pharynx and associated structures commonly caused by the Group A streptococci (GAS). There is a growing interest in discovering plant-based anti-inflammatory compounds as potential alternatives to conventional...

["Agricultural Science","Biochemistry","Cell Biology","Food Science and Technology","Infectious Diseases"]
doi:10.7717/peerj.3469
78 downloads
382 views

Empirical and mechanistic modeling indicate that pathogens transmitted via aerially dispersed inoculum follow a power law, resulting in dispersive epidemic waves. The spread parameter (b) of the power law model, which is an indicator of the distance of the epidemic...

["Ecology","Mathematical Biology","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.3465
219 downloads
398 views

Subclinical mastitis is a persistent problem in dairy farms worldwide. Environmental Escherichia coli is the bacterium predominantly responsible for this condition. In Thailand, subclinical mastitis in dairy cows is usually treated with various antibiotics, which...

["Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3431
121 downloads
610 views

Phytochemicals produced by plants, including at flowers, function in protection against plant diseases, and have a long history of use against trypanosomatid infection. Floral nectar and pollen, the sole food sources for many species of insect pollinators, contain...

["Ecology","Entomology","Parasitology","Plant Science","Infectious Diseases"]
doi:10.7717/peerj.3297
146 downloads
299 views

Tuberculosis is one of the world’s deadliest infectious disease with 1.5 millions deaths annually. It is imperative to discover novel compounds with potent activity against M. tuberculosis. In this study, susceptibilities of M. smegmatis to the octahedral ruthenium(II)...

["Biochemistry","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3252
118 downloads
396 views

Background The enzymatic degradation of quorums sensing (QS) molecules (called quorum quenching, QQ) has been considered as a promising anti-virulence therapy to treat biofilm-related infections and combat antibiotic resistance. The recently-discovered QQ enzyme...

["Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3251
154 downloads
729 views

Mayaro virus (MAYV) is an emergent sylvatic alphavirus in South America, related to sporadic outbreaks of a chikungunya-like human febrile illness accompanied by severe arthralgia. Despite its high potential for urban emergence, MAYV is still an obscure virus with...

["Biochemistry","Microbiology","Virology","Infectious Diseases"]
doi:10.7717/peerj.3245

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