Peer-reviewed Articles

120 downloads
432 views

Rhodomyrtone, a natural antimicrobial compound, displays potent activity against many Gram-positive pathogenic bacteria, comparable to last-defence antibiotics including vancomycin and daptomycin. Our previous studies pointed towards effects of rhodomyrtone on...

["Biochemistry","Computational Biology","Microbiology","Drugs and Devices","Infectious Diseases"]
doi:10.7717/peerj.2962
84 downloads
272 views

Streptococcus pneumoniae remains the leading causative pathogen in pediatric pneumonia and bacteremia throughout the world. The invasive pneumococcal disease (IPD) is known as isolation of S. pneumoniae from a normally sterile site (e.g., blood, cerebrospinal fluid,...

["Emergency and Critical Care","Epidemiology","Infectious Diseases","Pediatrics","Public Health"]
doi:10.7717/peerj.2941
120 downloads
621 views

From early 2012, a novel clone of vancomycin resistant Enterococcus faecium (assigned the multi locus sequence type ST796) was simultaneously isolated from geographically separate hospitals in south eastern Australia and New Zealand. Here we describe the complete...

["Evolutionary Studies","Genomics","Microbiology","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.2916
101 downloads
360 views

Klebsiella pneumoniae is responsible for numerous infections caused in hospitals, leading to mortality and morbidity. It has been evolving as a multi-drug resistant pathogen, acquiring multiple resistances such as such as horizontal gene transfer, transposon-mediated...

["Microbiology","Molecular Biology","Drugs and Devices","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.2896
42 downloads
173 views

Background Malaria elimination campaigns are planned or active in many countries. The effects of malaria elimination on immune responses such as antigen-specific IFN- γ responses are not well characterized. Methods IFN- γ responses to the P. falciparum antigens...

["Immunology","Infectious Diseases"]
doi:10.7717/peerj.2855
51 downloads
302 views

The emergence and spread of drug-resistance during treatment of many infectious diseases continue to degrade our ability to control and mitigate infection outcomes using therapeutic measures. While the coverage and efficacy of treatment remain key factors in the...

["Mathematical Biology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2817
75 downloads
298 views

Background Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment,...

["Microbiology","Infectious Diseases","Public Health","Metabolic Sciences"]
doi:10.7717/peerj.2833
152 downloads
662 views

G1P[8] rotaviruses are responsible for the majority of human rotavirus infections worldwide. The effect of universal mass vaccination with rotavirus vaccines on circulating G1P[8] rotaviruses is still poorly understood. Therefore we analyzed the complete genomes...

["Virology","Gastroenterology and Hepatology","Infectious Diseases"]
doi:10.7717/peerj.2733
140 downloads
268 views

Melioidosis, an infection caused by the facultative intracellular pathogen Burkholderia pseudomallei, has been classified as an emerging disease with the number of patients steadily increasing at an alarming rate. B. pseudomalleipossess various virulence determinants...

["Bioinformatics","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.2532
62 downloads
292 views

Tuberculosis is considered a leading cause of death worldwide. More than 95% of cases and deaths occur in low- and middle-income countries. In resource-limited countries, hospitals often lack adequate facilities to manage and isolate patients with infectious tuberculosis...

["Microbiology","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7717/peerj.2795
78 downloads
212 views

Background Daldinia eschscholtzii is a filamentous wood-inhabiting endophyte commonly found in woody plants. Here, we report the identification and characterization of nine D. eschscholtzii isolates from skin scrapings, nail clippings, and blood. Methods The nine...

["Mycology","Infectious Diseases","Pathology"]
doi:10.7717/peerj.2637
85 downloads
306 views

Many pathogenic mycobacteria are known to cause severe disease in humans and animals. M. avium subspecies paratuberculosis (Map) is the causative agent of Johne’s disease—a chronic wasting disease affecting ruminants such as cattle and sheep, responsible for significant...

["Genomics","Microbiology","Veterinary Medicine","Infectious Diseases"]
doi:10.7717/peerj.2793
97 downloads
381 views

Streptococcus pneumoniae is a pathogen that causes serious invasive infections, such as septicemia, meningitis and pneumonia in addition to mild upper respiratory tract infections. Protection from pneumococcal diseases is thought to be mediated mainly by serotype-specific...

["Immunology","Infectious Diseases"]
doi:10.7717/peerj.2737
139 downloads
1,523 views

One of the newest and strongest members of intercellular communicators, the Extracellular vesicles (EVs) and their enclosed RNAs; Extracellular RNAs (exRNAs) have been acknowledged as putative biomarkers and therapeutic targets for various diseases. Although a...

["Bioinformatics","Computational Biology","Infectious Diseases"]
doi:10.7717/peerj.2693
88 downloads
2,744 views

In 2013 approximately 37,000 people were living with HIV in Ecuador (prevalence 0.4%), representing a generalized epidemic where most new infections arise from sexual interactions in the general population. Studies that examine attitudes towards people living with...

["Global Health","Health Policy","HIV","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2726

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