Peer-reviewed Articles

108 downloads
346 views

Background Pretreatment platelet count has been reported as a potential tool to predict survival outcome in several solid tumors. However, the predictive value of pretreatment platelet count remains obscure in de novo acute myeloid leukemia (AML) excluding acute...

["Hematology","Internal Medicine","Oncology"]
doi:10.7717/peerj.4139
111 downloads
552 views

Background Tibetans have lived at high altitudes for thousands of years, and they have unique physiological traits that enable them to tolerate this hypoxic environment. However, the genetic basis of these traits is still unknown. As a sensitive and highly efficient...

["Molecular Biology","Hematology"]
doi:10.7717/peerj.3726
1 citation
143 downloads
801 views

Background Leukocyte concentrations follow a circadian pattern in mammals, with elevated values at times of potential contact with pathogens and parasites. We hypothesized that this pattern is disturbed after an immune challenge. Methods In Thailand, we captured...

["Animal Behavior","Ecology","Veterinary Medicine","Zoology","Hematology"]
doi:10.7717/peerj.3570
1 citation
198 downloads
950 views

Development of drug resistance limits the effectiveness of anticancer treatments. Understanding the molecular mechanisms triggering this event in tumor cells may lead to improved therapeutic strategies. Here we used RNA-seq to compare the transcriptomes of a murine...

["Molecular Biology","Hematology"]
doi:10.7717/peerj.3432
1 citation
213 downloads
742 views

Aim To investigate the association of C-MYC protein expression and risk stratification in mantle cell lymphoma (MCL), and to evaluate the utility of C-MYC protein as a prognostic biomarker in clinical practice. Methods We conducted immunohistochemical staining...

["Hematology","Oncology"]
doi:10.7717/peerj.3457
3 citations
275 downloads
759 views

Background ABO blood group is a hereditary factor of plasma levels of coagulation factor VIII (FVIII) and von Willebrand factor (VWF). Age and gender have been shown to influence FVIII, VWF, fibrinogen (Fbg), and ADAMTS13 (A disintegrin and metalloprotease with...

["Biochemistry","Global Health","Hematology","Translational Medicine"]
doi:10.7717/peerj.3156
178 downloads
802 views

Background Preanalytic factors such as time and temperature can have significant effects on laboratory test results. For example, ammonium concentration will increase 31% in blood samples stored at room temperature for 30 min before centrifugation. To reduce preanalytic...

["Biochemistry","Veterinary Medicine","Emergency and Critical Care","Gastroenterology and Hepatology","Hematology"]
doi:10.7717/peerj.2732
3 citations
226 downloads
860 views

This study compares and evaluates the prediction of hepatitis in Guangxi Province, China by using back propagation neural networks based genetic algorithm (BPNN-GA), generalized regression neural networks (GRNN), and wavelet neural networks (WNN). In order to compare...

["Epidemiology","Hematology","Infectious Diseases","Computational Science"]
doi:10.7717/peerj.2684
1 citation
1,062 downloads
1,026 views

Background Laparoscopic cholecystectomies (LC) are generally performed in a 12 mmHg-pressured pneumoperitoneum in a slight sitting position. Considerable thromboembolism risk arises in this operation due to pneumoperitoneum, operation position and risk factors...

["Anesthesiology and Pain Management","Gastroenterology and Hepatology","Hematology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.2375
3 citations
515 downloads
1,580 views

Despite the promise of hematological parameters and blood chemistry in monitoring the health of marine fishes, baseline data is often lacking for small fishes that comprise central roles in marine food webs. This study establishes blood chemistry and hematological...

["Aquaculture, Fisheries and Fish Science","Bioinformatics","Marine Biology","Veterinary Medicine","Hematology"]
doi:10.7717/peerj.2262
1 citation
198 downloads
739 views

Background. A “cafeteria” diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy....

["Anatomy and Physiology","Diabetes and Endocrinology","Hematology","Nutrition","Metabolic Sciences"]
doi:10.7717/peerj.2302
2 citations
275 downloads
1,336 views

Objective. Bone lesion is crucial for diagnosing and management of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin change (POEMS) syndrome, a rare plasma cell disorder. This study is to compare the effectiveness of X-ray skeletal survey...

["Hematology","Orthopedics","Radiology and Medical Imaging"]
doi:10.7717/peerj.2294
1 citation
299 downloads
893 views

Background. Geriatric syndromes (GS) exhibit high prevalence in patients with end-stage renal disease (ESRD) under chronic dialysis irrespective of age. We sought to determine whether GS influences medication adherence in ESRD patients. Methods. A prospective cohort...

["Evidence Based Medicine","Geriatrics","Hematology","Nephrology","Palliative Care"]
doi:10.7717/peerj.2122
2 citations
324 downloads
1,180 views

We previously reported that the inflammasome inhibitor cucurbitacin D (CuD) induces apoptosis in human leukemia cell lines. Here, we investigated the effects of CuD and a B-cell lymphoma extra-large (Bcl-xL) inhibitor on autophagy in peripheral blood lymphocytes...

["Cell Biology","Drugs and Devices","Hematology","Oncology"]
doi:10.7717/peerj.2026
5 citations
1,075 downloads
1,166 views

Background: Food insecurity and hidden hunger (micronutrient deficiency) affect about two billion people globally. Household food insecurity (HFI) has been shown to be associated with one or multiple micronutrient (MMN) deficiencies among women and children. Chronic...

["Hematology","Nutrition","Public Health","Women's Health"]
doi:10.7717/peerj.1945

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