Peer-reviewed Articles

64 downloads
314 views

Background To find the best individual chemotherapy for cancer patients, the efficacy of different chemotherapeutic drugs can be predicted by pretesting tumor samples in vitro via the chemotherapy-resistance (CTR)-Test®. Although drug combinations are widely used...

["Gynecology and Obstetrics","Oncology","Pharmacology"]
doi:10.7717/peerj.3030
78 downloads
438 views

LIMKi 3 is a specific selective LIMK inhibitor against LIMK1 and LIMK2, while LIMK1 and LIMK2 are the main regulators of actin cytoskeleton to participate in many cell activities. However, the effect of LIMKi 3 in porcine oocyte meiosis is still unclear. The present...

["Cell Biology","Developmental Biology","Gynecology and Obstetrics"]
doi:10.7717/peerj.2553
130 downloads
601 views

Background Cancer research is a national and international priority, with the efficiency and effectiveness of current anti-tumor therapies being one of the major challenges with which physicians are faced. Objective To assess the impact of exposure to tobacco smoke,...

["Epidemiology","Gynecology and Obstetrics","Oncology","Public Health","Women\u2019s Health"]
doi:10.7717/peerj.2448
1 citation
121 downloads
632 views

Introduction The aim of this study was to determine the incidence rates of endometrial hyperplasia (EH) and endometrial cancer (EC) in the Republic of Korea using national insurance claim data generated from 2009 to 2012. Materials and Methods Data that were generated...

["Epidemiology","Gynecology and Obstetrics","Women\u2019s Health"]
doi:10.7717/peerj.2374
174 downloads
1,101 views

Objectives. The frequency, predisposing factors and impact of urinary incontinence (UI) on quality of life (QoL) during pregnancy were investigated. Materials and Method. A preliminary cross-sectional survey was studied among pregnant women between January and...

["Gynecology and Obstetrics","Health Policy","Nursing","Urology","Women\u2019s Health"]
doi:10.7717/peerj.2283
89 downloads
536 views

Background. The ReproQuestionnaire (ReproQ) measures the client’s experience with maternity care, following the WHO responsiveness model. In 2015, the ReproQ was appointed as national client experience questionnaire and will be added to the national list of indicators...

["Gynecology and Obstetrics","Public Health","Women\u2019s Health","Science and Medical Education","Science Policy"]
doi:10.7717/peerj.2092
14 citations
512 downloads
1,964 views

Background. It is widely assumed that the uterine cavity in non-pregnant women is physiologically sterile, also as a premise to the long-held view that human infants develop in a sterile uterine environment, though likely reflecting under-appraisal of the extent...

["Microbiology","Molecular Biology","Anatomy and Physiology","Gynecology and Obstetrics","Women\u2019s Health"]
doi:10.7717/peerj.1602
1 citation
729 downloads
1,046 views

Current ovarian cancer treatment involves chemotherapy that has serious limitations, such as rapid clearance, unfavorable biodistribution and severe side effects. To overcome these limitations, drug delivery systems (DDS) have been developed to encapsulate chemotherapeutics...

["Drugs and Devices","Gynecology and Obstetrics","Oncology"]
doi:10.7717/peerj.1489
4 citations
340 downloads
1,353 views

Background. Preterm Premature Rupture of Membranes (PPROM) is a major leading cause of preterm births. While the cause for PPROM remains unidentified, it is anticipated to be due to subclinical infection, since a large proportion of PPROM patients display signs...

["Microbiology","Gynecology and Obstetrics"]
doi:10.7717/peerj.1398
1 citation
224 downloads
1,022 views

Ovarian cancer has a poor prognosis. Most patients are diagnosed with ovarian cancer when the disease has reached an advanced stage and cure rates are generally under 30%. Hence, early diagnosis of ovarian cancer is the best means to control the disease in the...

["Gynecology and Obstetrics","Oncology","Translational Medicine","Women\u2019s Health"]
doi:10.7717/peerj.1386
1 citation
123 downloads
940 views

The inconsistent use of hormonal contraceptive methods can result, during the first year of use, in one in twelve women still having an undesired pregnancy. This may lead to women experiencing fear of becoming pregnant (FBP). We have only found one study examining...

["Epidemiology","Gynecology and Obstetrics","Psychiatry and Psychology","Public Health","Women\u2019s Health"]
doi:10.7717/peerj.1200
6 citations
853 downloads
2,816 views

Implantation, trophoblast development and placentation are crucial processes in the establishment and development of normal pregnancy. Abnormalities of these processes can lead to pregnancy complications known as the great obstetrical syndromes: preeclampsia, intrauterine...

["Gynecology and Obstetrics","Immunology"]
doi:10.7717/peerj.691
1 citation
465 downloads
1,066 views

Obstetrical complications including preeclampsia, fetal growth restriction, preterm labor, preterm prelabor rupture of membranes and fetal demise are all the clinical endpoint of several underlying mechanisms (i.e., infection, inflammation, thrombosis, endocrine...

["Gynecology and Obstetrics","Hematology"]
doi:10.7717/peerj.653
6 citations
651 downloads
1,676 views

Objectives. Marijuana is the most commonly used illicit drug during pregnancy. Due to high lipophilicity, cannabinoids can easily penetrate physiological barriers like the human placenta and jeopardize the developing fetus. We evaluated the impact of cannabidiol...

["Gynecology and Obstetrics","Pharmacology"]
doi:10.7717/peerj.153
16 citations
1,766 downloads
16,854 views

Aim. There is no consensus about the normal fetal heart rate. Current international guidelines recommend for the normal fetal heart rate (FHR) baseline different ranges of 110 to 150 beats per minute (bpm) or 110 to 160 bpm. We started with a precise definition...

["Bioinformatics","Evidence Based Medicine","Gynecology and Obstetrics","Statistics"]
doi:10.7717/peerj.82

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