Peer-reviewed Articles

14 downloads
139 views

The past two decades have brought many important advances in our understanding of the hereditary susceptibility to cancer. Numerous studies have provided convincing evidence that identification of germline mutations associated with hereditary cancer syndromes can...

["Genomics","Oncology","Medical Genetics"]
doi:10.7717/peerj.3046
102 downloads
620 views

Background De novo transcriptome assembly of short reads is now a common step in expression analysis of organisms lacking a reference genome sequence. Several software packages are available to perform this task. Even if their results are of good quality it is...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.2988
54 downloads
551 views

Genomic heterogeneity of bacterial species is observed and studied in experimental evolution experiments and clinical diagnostics, and occurs as micro-diversity of natural habitats. The challenge for genome research is to accurately capture this heterogeneity with...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genomics","Microbiology"]
doi:10.7717/peerj.2997
64 downloads
328 views

Streptomyces sp. H-KF8 is an actinobacterial strain isolated from marine sediments of a Chilean Patagonian fjord. Morphological characterization together with antibacterial activity was assessed in various culture media, revealing a carbon-source dependent activity...

["Genomics","Microbiology"]
doi:10.7717/peerj.2912
54 downloads
233 views

Background The endemic Australian freshwater prawn, Macrobrachium koombooloomba, provides a model for exploring genes involved with freshwater adaptation because it is one of the relatively few Macrobrachium species that can complete its entire life cycle in freshwater....

["Aquaculture, Fisheries and Fish Science","Evolutionary Studies","Genomics","Marine Biology"]
doi:10.7717/peerj.2977
92 downloads
769 views

A high-quality draft genome for Proctacanthus coquilletti (Insecta: Diptera: Asilidae) is presented along with transcriptomes for 16 Diptera species from five families: Asilidae, Apioceridae, Bombyliidae, Mydidae, and Tabanidae. Genome sequencing reveals that P....

["Entomology","Genomics"]
doi:10.7717/peerj.2951
54 downloads
235 views

Background Multiple myeloma is a cancer which has a high occurrence rate and causes great injury to people worldwide. In recent years, many studies reported the effects of miRNA on the appearance of multiple myeloma. However, due to the differences of samples and...

["Genomics","Dermatology","Oncology"]
doi:10.7717/peerj.2831
86 downloads
383 views

The production of hydrogen and methane by geochemical reactions associated with the serpentinization of ultramafic rocks can potentially support subsurface microbial ecosystems independent of the photosynthetic biosphere. Methanogenic and methanotrophic microorganisms...

["Ecology","Environmental Sciences","Genomics","Microbiology"]
doi:10.7717/peerj.2945
56 downloads
304 views

Background Transposable element (TE) polymorphisms are important components of population genetic variation. The functional impacts of TEs in gene regulation and generating genetic diversity have been observed in multiple species, but the frequency and magnitude...

["Bioinformatics","Genomics","Plant Science"]
doi:10.7717/peerj.2942
50 downloads
162 views

Viroids are the smallest infectious agents, and their genomes consist of a short single strand of RNA that does not encode any protein. Chrysanthemum stunt viroid (CSVd), a member of the family Pospiviroidae, causes chrysanthemum stunt disease. Here, we report...

["Agricultural Science","Biodiversity","Genomics","Plant Science","Virology"]
doi:10.7717/peerj.2933
54 downloads
300 views

Understanding the processes that give rise to genomic variability in extant species is an active area of research within evolutionary biology. With the availability of whole genome sequences, it is possible to quantify different forms of variability such as variation...

["Genetics","Genomics"]
doi:10.7717/peerj.2901
77 downloads
275 views

Corynespora cassiicola is a common plant pathogen that causes leaf spot disease in a broad range of crop, and it heavily affect rubber trees in Malaysia (Hsueh, 2011; Nghia et al., 2008). The isolation of UM 591 from a patient’s contact lens indicates the pathogenic...

["Genomics","Microbiology"]
doi:10.7717/peerj.2841
131 downloads
567 views

Background Few studies have investigated the gut microbiome of infants, fewer still preterm infants. In this study we sought to quantify and interrogate the resistome within a cohort of premature infants using shotgun metagenomic sequencing. We describe the gut...

["Computational Biology","Genomics","Microbiology","Pediatrics","Public Health"]
doi:10.7717/peerj.2928
120 downloads
618 views

From early 2012, a novel clone of vancomycin resistant Enterococcus faecium (assigned the multi locus sequence type ST796) was simultaneously isolated from geographically separate hospitals in south eastern Australia and New Zealand. Here we describe the complete...

["Evolutionary Studies","Genomics","Microbiology","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.2916
51 downloads
191 views

Methylation of cytosine in DNA is one of the most important epigenetic modifications in eukaryotes and plays a crucial role in the regulation of gene activity and the maintenance of genomic integrity. DNA methylation and other epigenetic mechanisms affect the development,...

["Biodiversity","Genomics","Plant Science"]
doi:10.7717/peerj.2889

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