Peer-reviewed Articles

17 downloads
543 views

Aim To perform a systematic review and meta-analysis of the weekend effect on the mortality of patients with upper gastrointestinal bleeding(UGIB). Methods The review protocol has been registered in the PROSPERO International Prospective Register of Systematic...

["Emergency and Critical Care","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.4248
179 downloads
553 views

Cherries are fruits containing fiber and bioactive compounds (e.g., polyphenolics) with the potential of helping patients with diabetes and weight disorders, a phenomenon likely related to changes in the complex host-microbiota milieu. The objective of this study...

["Biochemistry","Microbiology","Molecular Biology","Diabetes and Endocrinology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.4195
45 downloads
319 views

Background The prognosis of gastric cancer is difficult to determine, although clinical indicators provide valuable evidence. Methods In this study, using screened biomarkers of gastric cancer in combination with random forest variable hunting and multivariable...

["Bioinformatics","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.4204
59 downloads
527 views

The core antigen of the hepatitis C virus (HCV Ag) presents an alternative marker to HCV RNA when screening patients for HCV viremia. This study sought to evaluate the utility of HCV Ag as a marker to assess active HCV infection in individuals residing in an HCV-endemic...

["Molecular Biology","Virology","Epidemiology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.4008
1 citation
178 downloads
1,026 views

Aim To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. Methods The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical...

["Clinical Trials","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.3654
112 downloads
672 views

The death-associated protein kinase 1 (DAPK1) can act as an oncogene or a tumor suppressor gene depending on the cellular context as well as external stimuli. Our study aims to investigate the prognostic significance of DAPK1 in liver cancer in both mRNA and protein...

["Biochemistry","Gastroenterology and Hepatology","Oncology","Translational Medicine","Histology"]
doi:10.7717/peerj.3568
1 citation
171 downloads
698 views

Background As the fifth most common cancer worldwide, Hepatocellular carcinoma (HCC) is also the third most common cause of cancer-related death in China. Several lncRNAs have been demonstrated to be associated with occurrence and prognosis of HCC. However, identification...

["Bioinformatics","Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3575
81 downloads
506 views

Background Other studies have assessed nonadherence to proton pump inhibitors (PPIs), but none has developed a screening test for its detection. Objectives To construct and internally validate a predictive model for nonadherence to PPIs. Methods This prospective...

["Drugs and Devices","Epidemiology","Gastroenterology and Hepatology","Pharmacology","Human-Computer Interaction"]
doi:10.7717/peerj.3455
2 citations
304 downloads
1,531 views

Bariatric surgery is highly successful in improving health compared to conventional dietary treatments. It has been suggested that the gut microbiota is a relevant factor in weight loss after bariatric surgery. Considering that bariatric procedures cause different...

["Genomics","Microbiology","Gastroenterology and Hepatology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3443
292 downloads
765 views

Gastric cancer is an aggressive cancer that is often diagnosed late. Early detection and treatment require a better understanding of the molecular pathology of the disease. The present study combined data on gene expression and regulatory levels (microRNA, methylation,...

["Bioinformatics","Genetics","Genomics","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3385
146 downloads
539 views

Background Several studies report aberrant expression of sine oculis homeobox (SIX) homolog family members during cancer development and progression. SIX4 participates in organ development, such as myogenesis and neurogenesis. However, the expression and clinical...

["Biochemistry","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3394
139 downloads
427 views

Helicobacter pylori (H. pylori) is one of the most common human bacterial infections with prevalence rates between 10–80% depending upon geographical location, age and socioeconomic status. H. pylori is commonly found in patients complaining of dyspepsia and is...

["Gastroenterology and Hepatology","HIV"]
doi:10.7717/peerj.3392
2 citations
284 downloads
951 views

Prebiotics are selectively fermentable dietary compounds that result in changes in the composition and/or activity of the intestinal microbiota, thus conferring benefits upon host health. In veterinary medicine, commercially available products containing prebiotics...

["Bioinformatics","Microbiology","Veterinary Medicine","Gastroenterology and Hepatology","Nutrition"]
doi:10.7717/peerj.3184
1 citation
277 downloads
752 views

Background The promising postsurgical weight loss and remission of type 2 diabetes (T2D) from bariatric surgery can be attributed to modified eating physiology after surgical procedures. We sought to investigate the changes in the parameters of consumption behaviors...

["Diabetes and Endocrinology","Gastroenterology and Hepatology","Psychiatry and Psychology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3090
2 citations
142 downloads
468 views

Background and Aim The infection of Helicobacter pylori (H. pylori) is acquired in childhood and the prevalence vary greatly in different countries and regions. The study aimed to investigate the characteristics of H. pylori infection among children with gastrointestinal...

["Gastroenterology and Hepatology","Pediatrics"]
doi:10.7717/peerj.2937

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