Peer-reviewed Articles

206 downloads
577 views

Background Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO), the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously...

["Food Science and Technology","Microbiology","Gastroenterology and Hepatology","Nutrition","Pediatrics"]
doi:10.7717/peerj.2876
41 downloads
211 views

Background Liver disease has become an important cause of morbidity and mortality even in those HIV-infected individuals who are devoid of hepatitis virus co-infection. The aim of this study was to evaluate the degree of hepatic fibrosis and the role of associated...

["Gastroenterology and Hepatology","HIV","Public Health"]
doi:10.7717/peerj.2867
115 downloads
497 views

G1P[8] rotaviruses are responsible for the majority of human rotavirus infections worldwide. The effect of universal mass vaccination with rotavirus vaccines on circulating G1P[8] rotaviruses is still poorly understood. Therefore we analyzed the complete genomes...

["Virology","Gastroenterology and Hepatology","Infectious Diseases"]
doi:10.7717/peerj.2733
133 downloads
319 views

This large-scale, controlled cohort study estimated the risks of lung cancer in patients with gastro-esophageal reflux disease (GERD) in Taiwan. We conducted this population-based study using data from the National Health Insurance Research Database of Taiwan during...

["Epidemiology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.2753
43 downloads
346 views

Background Preanalytic factors such as time and temperature can have significant effects on laboratory test results. For example, ammonium concentration will increase 31% in blood samples stored at room temperature for 30 min before centrifugation. To reduce preanalytic...

["Biochemistry","Veterinary Medicine","Emergency and Critical Care","Gastroenterology and Hepatology","Hematology"]
doi:10.7717/peerj.2732
63 downloads
372 views

This study investigated the mechanism of protein disulfide-isomerase A3 (PDIA3)-induced visceral hypersensitivity in irritable bowel syndrome (IBS). Rats were treated with saline (control), acetic acid and restraint stress (IBS model), empty vector (RNAi control)...

["Allergy and Clinical Immunology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.2644
117 downloads
584 views

Background Observational studies have shown inconsistent results regarding alcohol consumption and risk of fatty liver. We performed a meta-analysis of published literature to investigate the association between alcohol consumption and fatty liver disease (FLD)....

["Evidence Based Medicine","Gastroenterology and Hepatology","Public Health"]
doi:10.7717/peerj.2633
123 downloads
405 views

Background Several genes and their single nucleotide polymorphisms (SNPs) are associated with either spontaneous resolution of hepatitis C infection or better treatment-induced viral clearance. We tested a cohort of intravenous drug users (IVDU) diagnosed with...

["Gastroenterology and Hepatology","Immunology","Infectious Diseases","Medical Genetics"]
doi:10.7717/peerj.2576
85 downloads
448 views

Antibiotics are a vital and commonly used therapeutic tool, but their use also results in profound changes in the intestinal microbiota that can, in turn, have significant health consequences. Understanding how the microbiota recovers after antibiotic treatment...

["Bioinformatics","Microbiology","Gastroenterology and Hepatology","Immunology","Nutrition"]
doi:10.7717/peerj.2518
261 downloads
965 views

Background Parenteral nutrition associated cholestasis (PNAC) is a frequently observed pathology in extremely low birth weight (ELBW) infants. Its pathogenesis is determined by the composition and duration of parenteral nutrition (PN) as well as the tolerance of...

["Gastroenterology and Hepatology","Nutrition","Pediatrics"]
doi:10.7717/peerj.2483
983 downloads
606 views

Background Laparoscopic cholecystectomies (LC) are generally performed in a 12 mmHg-pressured pneumoperitoneum in a slight sitting position. Considerable thromboembolism risk arises in this operation due to pneumoperitoneum, operation position and risk factors...

["Anaesthesiology and Pain Management","Gastroenterology and Hepatology","Hematology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.2375
1 citation
161 downloads
635 views

Purpose. The purpose of this study was to evaluate the technical and diagnostic performance of sub-milliSievert ultralow-dose (ULD) CT colonograpy (CTC) in the detection of colonic and extracolonic lesions. Materials and Methods. CTC with standard dose (SD) and...

["Gastroenterology and Hepatology","Radiology and Medical Imaging"]
doi:10.7717/peerj.1883
1 citation
111 downloads
713 views

Crohn’s disease (CD) is a prominent type of inflammatory bowel disease (IBD) that can affect any part of the gastrointestinal tract. CD is known to have higher prevalence in the Western countries, but the number of cases has been increasing in the past decades...

["Genetics","Molecular Biology","Gastroenterology and Hepatology","Medical Genetics"]
doi:10.7717/peerj.1843
412 downloads
1,150 views

During the past decade, irreversible electroporation (IRE) ablation has emerged as a promising tool for the treatment of multiple diseases including hepatic cancer. However, the mechanisms behind the tissue regeneration following IRE ablation have not been investigated....

["Bioengineering","Developmental biology","Gastroenterology and hepatology","Surgery and surgical specialties","Histology"]
doi:10.7717/peerj.1571
161 downloads
588 views

Introduction. Colorectal cancer is one of the most frequent cancers in the world and liver metastases are seen in up to 19% of patients with colorectal cancers. Detection of liver metastases is not only vital for sufficient treatment and survival, but also for...

["Clinical Trials","Gastroenterology and Hepatology","Radiology and Medical Imaging","Surgery and Surgical Specialties"]
doi:10.7717/peerj.1532

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