Peer-reviewed Articles

57 downloads
261 views

Backgrounds and Aims Melanosis coli (MC) is a noninflammatory, benign, and reversible colonic disorder, but its detection rates in China are unclear. We therefore aimed to analyze the epidemiological characteristics of MC in China. Methods We assessed the detection...

["Epidemiology","Evidence Based Medicine","Gastroenterology and Hepatology","Pathology"]
doi:10.7717/peerj.4483
49 downloads
242 views

Purpose This study was performed to investigate the expression pattern of Wnt inhibitory factor 1 (Wif1) and β-catenin during anorectal development in normal and anorectal malformation (ARM) embryos and the possible role of Wif1 and β-catenin in the pathogenesis...

["Developmental Biology","Gastroenterology and Hepatology","Pediatrics"]
doi:10.7717/peerj.4445
89 downloads
482 views

Background In this study, the long-term efficacy of hepatitis B virus (HBV) vaccination was assessed using seroprevalence and an age–period–cohort (APC) model of HBV seromarkers among university entrants 30 years after the introduction of the national neonatal...

["Epidemiology","Gastroenterology and Hepatology","Global Health","Infectious Diseases","Public Health"]
doi:10.7717/peerj.4297
98 downloads
679 views

Liver fibrosis is a disease that causes high morbidity and has become a major health problem. Liver fibrosis can lead to the end stage of liver diseases (livercirrhosisand hepatocellularcarcinoma). Currently, liver transplantation is the only effective treatment...

["Cell Biology","Gastroenterology and Hepatology","Translational Medicine"]
doi:10.7717/peerj.4336
85 downloads
365 views

Objectives To investigate the frequency and prognostic role of deficient mismatch repair (dMMR) and RAS mutation in Chinese patients with colorectal carcinoma. Methods Clinical and pathological information from 813 patients were reviewed and recorded. Expression...

["Gastroenterology and Hepatology","Oncology","Pathology","Medical Genetics"]
doi:10.7717/peerj.4341
100 downloads
465 views

Background Equine metabolic syndrome (EMS) is associated with insulin dysregulation, which often manifests as post-prandial hyperinsulinemia. Circulating concentrations of the incretin hormone, glucagon-like peptide-1 (GLP-1) correlate with an increased insulin...

["Veterinary Medicine","Diabetes and Endocrinology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.4316
139 downloads
884 views

Aim To perform a systematic review and meta-analysis of the weekend effect on the mortality of patients with upper gastrointestinal bleeding(UGIB). Methods The review protocol has been registered in the PROSPERO International Prospective Register of Systematic...

["Emergency and Critical Care","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.4248
344 downloads
1,118 views

Cherries are fruits containing fiber and bioactive compounds (e.g., polyphenolics) with the potential of helping patients with diabetes and weight disorders, a phenomenon likely related to changes in the complex host-microbiota milieu. The objective of this study...

["Biochemistry","Microbiology","Molecular Biology","Diabetes and Endocrinology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.4195
144 downloads
628 views

Background The prognosis of gastric cancer is difficult to determine, although clinical indicators provide valuable evidence. Methods In this study, using screened biomarkers of gastric cancer in combination with random forest variable hunting and multivariable...

["Bioinformatics","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.4204
1 citation
136 downloads
732 views

The core antigen of the hepatitis C virus (HCV Ag) presents an alternative marker to HCV RNA when screening patients for HCV viremia. This study sought to evaluate the utility of HCV Ag as a marker to assess active HCV infection in individuals residing in an HCV-endemic...

["Molecular Biology","Virology","Epidemiology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.4008
1 citation
240 downloads
1,166 views

Aim To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. Methods The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical...

["Clinical Trials","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.3654
154 downloads
856 views

The death-associated protein kinase 1 (DAPK1) can act as an oncogene or a tumor suppressor gene depending on the cellular context as well as external stimuli. Our study aims to investigate the prognostic significance of DAPK1 in liver cancer in both mRNA and protein...

["Biochemistry","Gastroenterology and Hepatology","Oncology","Translational Medicine","Histology"]
doi:10.7717/peerj.3568
3 citations
235 downloads
899 views

Background As the fifth most common cancer worldwide, Hepatocellular carcinoma (HCC) is also the third most common cause of cancer-related death in China. Several lncRNAs have been demonstrated to be associated with occurrence and prognosis of HCC. However, identification...

["Bioinformatics","Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.3575
102 downloads
612 views

Background Other studies have assessed nonadherence to proton pump inhibitors (PPIs), but none has developed a screening test for its detection. Objectives To construct and internally validate a predictive model for nonadherence to PPIs. Methods This prospective...

["Drugs and Devices","Epidemiology","Gastroenterology and Hepatology","Pharmacology","Human-Computer Interaction"]
doi:10.7717/peerj.3455
2 citations
385 downloads
1,755 views

Bariatric surgery is highly successful in improving health compared to conventional dietary treatments. It has been suggested that the gut microbiota is a relevant factor in weight loss after bariatric surgery. Considering that bariatric procedures cause different...

["Genomics","Microbiology","Gastroenterology and Hepatology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3443

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