Peer-reviewed Articles

26 downloads
154 views

Purpose To assess the overall quality of published urological meta-analyses and identify predictive factors for high quality. Materials and Methods We systematically searched PubMed to identify meta-analyses published from January 1st, 2011 to December 31st, 2015...

["Epidemiology","Evidence Based Medicine","Urology"]
doi:10.7717/peerj.3129
60 downloads
175 views

Background The diagnostic values of interferon-gamma release assays (IGRA) in tuberculosis (TB) vary a lot with different site of infections, with especially higher sensitivities in chronic forms of TB such as tuberculosis of the lymph node. We conducted a meta-analysis...

["Evidence Based Medicine","Infectious Diseases"]
doi:10.7717/peerj.3136
89 downloads
327 views

Introduction Hospital readmissions are common, expensive, and a key target of the Medicare Value Based Purchasing (VBP) program. Validated risk assessment tools such as the HOSPITAL score and LACE index have been developed to identify patients at high risk of hospital...

["Evidence Based Medicine","Health Policy","Public Health"]
doi:10.7717/peerj.3137
58 downloads
256 views

Previous studies have investigated the association between cytotoxic T-lymphocyte antigen-4 (CTLA-4) polymorphisms and breast cancer susceptibility, but the results remained inconsistent. Therefore, we evaluated the relationship between four common CTLA-4 polymorphisms...

["Evidence Based Medicine","Oncology","Medical Genetics"]
doi:10.7717/peerj.2815
240 downloads
637 views

Background New reliable devices for range of motion (ROM) measures in older adults are necessary to improve knowledge about the functional capability in this population. Dorsiflexion ROM limitation is associated with ankle injuries, foot pain, lower limb disorders,...

["Evidence Based Medicine","Geriatrics","Kinesiology"]
doi:10.7717/peerj.2820
163 downloads
478 views

MicroRNAs (miRNAs) may promote the development and progression of human cancers. Therefore, components of the miRNA biogenesis pathway may play critical roles in human cancer. Single nucleotide polymorphisms (SNPs) or mutations in genes involved in the miRNA biogenesis...

["Genetics","Epidemiology","Evidence Based Medicine","Oncology"]
doi:10.7717/peerj.2706
177 downloads
735 views

Background Observational studies have shown inconsistent results regarding alcohol consumption and risk of fatty liver. We performed a meta-analysis of published literature to investigate the association between alcohol consumption and fatty liver disease (FLD)....

["Evidence Based Medicine","Gastroenterology and Hepatology","Public Health"]
doi:10.7717/peerj.2633
229 downloads
522 views

Background The benefit of maintenance therapy has been confirmed in patients with non-progressing non-small cell lung cancer (NSCLC) after first-line therapy by many trials and meta-analyses. However, since few head-to-head trials between different regimens have...

["Evidence Based Medicine","Oncology","Respiratory Medicine"]
doi:10.7717/peerj.2550
3 citations
451 downloads
1,581 views

Context Necrotizing enterocolitis (NEC) is the most frequent gastrointestinal emergency in neonates. The microbiome of the preterm gut may regulate the integrity of the intestinal mucosa. Probiotics may positively contribute to mucosal integrity, potentially reducing...

["Clinical Trials","Drugs and Devices","Evidence Based Medicine","Pediatrics"]
doi:10.7717/peerj.2429
186 downloads
577 views

Introduction Hospital readmissions are common, expensive, and a key target of the Medicare Value Based Purchasing (VBP) program. Risk assessment tools have been developed to identify patients at high risk of hospital readmission so they can be targeted for interventions...

["Evidence Based Medicine","Health Policy","Internal Medicine"]
doi:10.7717/peerj.2441
194 downloads
577 views

8-Hydroxyquinoline and derivatives exhibit multifunctional properties, including antioxidant, antineurodegenerative, anticancer, anti-inflammatory and antidiabetic activities. In biological systems, elevation of intracellular calcium can cause calpain activation,...

["Neuroscience","Evidence Based Medicine","Neurology"]
doi:10.7717/peerj.2389
490 downloads
1,121 views

Background: Digital medicine and smartphone-enabled health technologies provide a novel source of human health and human biology data. However, in part due to its intricacies, few methods have been established to analyze and interpret data in this domain. We previously...

["Cardiology","Evidence Based Medicine","Translational Medicine","Statistics","Computational Science"]
doi:10.7717/peerj.2284
1 citation
638 downloads
3,821 views

Objective. Probiotics have been reported to support healthy digestive and immune function, aid in protein absorption, and decrease inflammation. Further, a trend to increase vertical jump power has been observed following co-administration of protein and probiotics...

["Clinical Trials","Evidence Based Medicine","Nutrition"]
doi:10.7717/peerj.2276
142 downloads
1,514 views

Introduction. Most documented rare diseases have genetic origin. Because of their low individual frequency, an initial diagnosis based on phenotypic symptoms is not always easy, as practitioners might never have been exposed to patients suffering from the relevant...

["Bioinformatics","Evidence Based Medicine","Translational Medicine","Science and Medical Education","Computational Science"]
doi:10.7717/peerj.2211
1 citation
116 downloads
823 views

Background. Quantitative ultrasound measures are influenced by multiple external factors including examiner scanning force. Force feedback may foster the acquisition of reliable morphometry measures under a variety of scanning conditions. The purpose of this study...

["Evidence Based Medicine","Kinesiology","Radiology and Medical Imaging","Science and Medical Education","Human\u2013Computer Interaction"]
doi:10.7717/peerj.2146

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