Peer-reviewed Articles

14 downloads
240 views

Ginsenoside Rk1 (G-Rk1) is a unique component created by processing the ginseng plant (mainly Sung Ginseng (SG)) at high temperatures. The aim of our study was to systematically review the pharmacological effects of G-Rk1. We utilized and manually searched eight...

["Plant Science","Evidence Based Medicine","Pharmacology"]
doi:10.7717/peerj.3993
49 downloads
223 views

Bone marrow stimulation may be applied to regenerate focal cartilage defects, but generally results in transient clinical improvement and formation of fibrocartilage rather than hyaline cartilage. Tissue engineering and regenerative medicine strive to develop new...

["Bioengineering","Evidence Based Medicine","Orthopedics","Rheumatology","Translational Medicine"]
doi:10.7717/peerj.3927
219 downloads
1,475 views

Objectives Compare the immediate effects of a Neurodynamic Mobilization (NM) treatment or foam roller (FR) treatment after DOMS. Design Double blind randomised clinical trial. Setting The participants performed 100 drop jumps (5 sets of 20 repetitions, separated...

["Clinical Trials","Evidence Based Medicine","Geriatrics","Nursing","Rheumatology"]
doi:10.7717/peerj.3908
39 downloads
178 views

Background In late 2015, cut-off points were published for foveal thickness to diagnose diabetic macular oedema taking into account the presence of intraretinal fluid using optical coherence tomography (OCT) in primary care patients (90 µm in the presence of intraretinal...

["Diabetes and Endocrinology","Epidemiology","Evidence Based Medicine","Ophthalmology","Public Health"]
doi:10.7717/peerj.3922
102 downloads
407 views

Background High mobility group box 1 (HMGB1) is a well-known damage-related alarmin that participates in cellular inflammatory responses. However, the mechanisms leading to HMGB1 release in inflammatory conditions and the therapeutic agents that could prevent it...

["Biotechnology","Toxicology","Drugs and Devices","Evidence Based Medicine","Pharmacology"]
doi:10.7717/peerj.3808
148 downloads
496 views

Introduction Different types of headaches and TMJ click influence the masseter muscle activity. The aim of this study was to assess the trend of energy level of the electromyography (EMG) activity of the masseter muscle during open-close clench cycles in migraine...

["Bioengineering","Computational Biology","Evidence Based Medicine","Radiology and Medical Imaging","Translational Medicine"]
doi:10.7717/peerj.3556
1 citation
166 downloads
433 views

Background Quercus infectoria G. Olivier (Fagaceae) nutgalls have been widely employed in traditional Asian medicine for several treatments, especially wounds and skin disorders. However, the effects of this plant on wound healing have not yet been clearly elucidated....

["Dermatology","Diabetes and Endocrinology","Evidence Based Medicine"]
doi:10.7717/peerj.3608
1 citation
299 downloads
676 views

Aim To evaluate the effects of sodium-glucose co-transporter 2 (SGLT2) inhibition on renal function and albuminuria in patients with type 2 diabetes. Methods We conducted systematic searches of PubMed, Embase and Cochrane Central Register of Controlled Trials up...

["Diabetes and Endocrinology","Evidence Based Medicine","Nephrology"]
doi:10.7717/peerj.3405
1 citation
96 downloads
469 views

Background Little is known about the role of dietary intake in obstructive sleep apnea (OSA), which could prove important in improving clinical outcomes for people with obesity and/or cardiovascular disease within these populations. Reduction in energy intake typically...

["Epidemiology","Evidence Based Medicine","Nutrition","Respiratory Medicine","Metabolic Sciences"]
doi:10.7717/peerj.3259
1 citation
97 downloads
476 views

Purpose To assess the overall quality of published urological meta-analyses and identify predictive factors for high quality. Materials and Methods We systematically searched PubMed to identify meta-analyses published from January 1st, 2011 to December 31st, 2015...

["Epidemiology","Evidence Based Medicine","Urology"]
doi:10.7717/peerj.3129
172 downloads
415 views

Background The diagnostic values of interferon-gamma release assays (IGRA) in tuberculosis (TB) vary a lot with different site of infections, with especially higher sensitivities in chronic forms of TB such as tuberculosis of the lymph node. We conducted a meta-analysis...

["Evidence Based Medicine","Infectious Diseases"]
doi:10.7717/peerj.3136
1 citation
298 downloads
940 views

Introduction Hospital readmissions are common, expensive, and a key target of the Medicare Value Based Purchasing (VBP) program. Validated risk assessment tools such as the HOSPITAL score and LACE index have been developed to identify patients at high risk of hospital...

["Evidence Based Medicine","Health Policy","Public Health"]
doi:10.7717/peerj.3137
132 downloads
430 views

Previous studies have investigated the association between cytotoxic T-lymphocyte antigen-4 (CTLA-4) polymorphisms and breast cancer susceptibility, but the results remained inconsistent. Therefore, we evaluated the relationship between four common CTLA-4 polymorphisms...

["Evidence Based Medicine","Oncology","Medical Genetics"]
doi:10.7717/peerj.2815
1 citation
409 downloads
1,006 views

Background New reliable devices for range of motion (ROM) measures in older adults are necessary to improve knowledge about the functional capability in this population. Dorsiflexion ROM limitation is associated with ankle injuries, foot pain, lower limb disorders,...

["Evidence Based Medicine","Geriatrics","Kinesiology"]
doi:10.7717/peerj.2820
1 citation
331 downloads
810 views

MicroRNAs (miRNAs) may promote the development and progression of human cancers. Therefore, components of the miRNA biogenesis pathway may play critical roles in human cancer. Single nucleotide polymorphisms (SNPs) or mutations in genes involved in the miRNA biogenesis...

["Genetics","Epidemiology","Evidence Based Medicine","Oncology"]
doi:10.7717/peerj.2706

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