Peer-reviewed Articles

54 downloads
262 views

Background Exergames are a new form of rehabilitation that combine the characteristics of physical exercise and the benefits of non-immersive virtual reality (VR). Effects of this novel therapy in women fibromyalgia are still unknown. The objective was to evaluate...

["Clinical Trials","Kinesiology","Women\u2019s Health"]
doi:10.7717/peerj.3211
126 downloads
693 views

Drug repositioning (i.e., drug repurposing) is the process of discovering new uses for marketed drugs. Historically, such discoveries were serendipitous. However, the rapid growth in electronic clinical data and text mining tools makes it feasible to systematically...

["Bioinformatics","Clinical Trials","Drugs and Devices","Oncology","Statistics"]
doi:10.7717/peerj.3154
385 downloads
974 views

This study investigated whether a yoga exercise intervention influenced the sustained attention and discrimination function in children with ADHD. Forty-nine participants (mean age = 10.50 years) were assigned to either a yoga exercise or a control group. Participants...

["Clinical Trials","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.2883
3 citations
458 downloads
1,589 views

Context Necrotizing enterocolitis (NEC) is the most frequent gastrointestinal emergency in neonates. The microbiome of the preterm gut may regulate the integrity of the intestinal mucosa. Probiotics may positively contribute to mucosal integrity, potentially reducing...

["Clinical Trials","Drugs and Devices","Evidence Based Medicine","Pediatrics"]
doi:10.7717/peerj.2429
2 citations
129 downloads
694 views

Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. The methodologies for generating tolAPC vary greatly...

["Clinical Trials","Immunology","Translational Medicine","Computational Science"]
doi:10.7717/peerj.2300
1 citation
639 downloads
3,829 views

Objective. Probiotics have been reported to support healthy digestive and immune function, aid in protein absorption, and decrease inflammation. Further, a trend to increase vertical jump power has been observed following co-administration of protein and probiotics...

["Clinical Trials","Evidence Based Medicine","Nutrition"]
doi:10.7717/peerj.2276
2 citations
362 downloads
2,367 views

Background. Imaging biomarkers hold tremendous promise for precision medicine clinical applications. Development of such biomarkers relies heavily on image post-processing tools for automated image quantitation. Their deployment in the context of clinical research...

["Bioinformatics","Clinical Trials","Oncology","Radiology and Medical Imaging"]
doi:10.7717/peerj.2057
2 citations
206 downloads
1,038 views

The objective of the study was to examine the feasibility and benefits of a group resistance training exercise programme for improving muscle function in institutionalised older adults. A feasibility and acceptability study was designed for a residential aged care...

["Clinical Trials","Geriatrics","Kinesiology","Public Health"]
doi:10.7717/peerj.2018
4 citations
461 downloads
1,564 views

Background. Due to inadequate UV exposure, intake of small quantities of vitamin D is recommended to prevent musculoskeletal disease. Both basic science and observational literature strongly suggest that higher doses may benefit specific populations and have non-musculoskeletal...

["Clinical Trials","Diabetes and Endocrinology","Evidence Based Medicine","Nutrition","Pediatrics"]
doi:10.7717/peerj.1701
1 citation
211 downloads
926 views

Over the past 60 years, the Mycobacterium bovis bacille Calmette–Guérin (BCG) has been used worldwide to prevent tuberculosis (TB). However, BCG has shown a very variable efficacy in different trials, offering a wide range of protection in adults against pulmonary...

["Mathematical Biology","Clinical Trials","Epidemiology","Infectious Diseases"]
doi:10.7717/peerj.1513
2 citations
398 downloads
1,687 views

Background. Pharmacogenomic testing has the potential to improve the safety and efficacy of pharmacotherapy, but clinical application of pharmacogenetic knowledge has remained uncommon. Clinical Decision Support (CDS) systems could help overcome some of the barriers...

["Clinical trials","Drugs and devices","Health policy","Science policy","Human-Computer interaction"]
doi:10.7717/peerj.1671
2 citations
270 downloads
2,063 views

The validity of studies that assess the effectiveness of an intervention (EoI) depends on variables such as the type of study design, the quality of their methodology, and the participants enrolled. Five leading veterinary journals and 5 leading human medical journals...

["Veterinary medicine","Clinical trials","Evidence based medicine","Translational medicine"]
doi:10.7717/peerj.1649
134 downloads
713 views

The effects of isoflurane on the determinants of blood flow during Coronary Artery Bypass Graft (CABG) surgery are not completely understood. This study characterized the influence of isoflurane on the diastolic Pressure-Flow (P-F) relationship and Critical Occlusion...

["Anaesthesiology and pain management","Cardiology","Clinical trials","Emergency and critical care","Surgery and surgical specialties"]
doi:10.7717/peerj.1619
13 citations
1,543 downloads
9,151 views

Background. Mobile health and digital medicine technologies are becoming increasingly used by individuals with common, chronic diseases to monitor their health. Numerous devices, sensors, and apps are available to patients and consumers–some of which have been...

["Clinical trials","Health policy","Translational medicine"]
doi:10.7717/peerj.1554
2 citations
187 downloads
693 views

Introduction. Colorectal cancer is one of the most frequent cancers in the world and liver metastases are seen in up to 19% of patients with colorectal cancers. Detection of liver metastases is not only vital for sufficient treatment and survival, but also for...

["Clinical Trials","Gastroenterology and Hepatology","Radiology and Medical Imaging","Surgery and Surgical Specialties"]
doi:10.7717/peerj.1532

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