Peer-reviewed Articles

23 downloads
181 views

Background Good results of drug-eluting balloon (DEB) use are achieved in in-stent restenosis (ISR) lesions, small vessel disease, long lesions, and bifurcations. However, few reports exist about DEB use in acute myocardial infarction (AMI) with ISR. This study’s...

["Cardiology"]
doi:10.7717/peerj.4646
66 downloads
303 views

Background Kawasaki disease (KD) is an immune-mediated systemic vasculitis, and infection plays an important role in the pathophysiology of KD. The susceptibility to infectious disease in patients with KD remains largely unclear. This study aimed to investigate...

["Allergy and Clinical Immunology","Cardiology","Immunology","Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.4539
71 downloads
425 views

Background Patients with acute myocardial infarction (AMI) and bundle-branch block have poor prognoses. The new European Society of Cardiology guideline suggests a primary percutaneous coronary intervention strategy when persistent ischemic symptoms occur in patients...

["Cardiology"]
doi:10.7717/peerj.4497
88 downloads
906 views

RNA editing modifies transcripts and may alter their regulation or function. In humans, the most common modification is adenosine to inosine (A-to-I). We examined the global characteristics of RNA editing in 4,301 human tissue samples. More than 1.6 million A-to-I...

["Computational Biology","Genetics","Genomics","Cardiology","Computational Science"]
doi:10.7717/peerj.4466
80 downloads
751 views

Objectives To assess and compare the predictive ability of three risk evaluation systems (SinoSCORE, EuroSCORE II and the STS risk evaluation system) in patients aged ≥70, and who underwent coronary artery bypass grafting (CABG) in East China. Methods Three risk...

["Cardiology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4413
90 downloads
594 views

Background Although several studies have identified risk factors for high blood pressure (BP), data from Afro-Caribbean populations are limited. Additionally, less is known about how putative risk factors operate in young adults and how social factors influence...

["Cardiology","Epidemiology","Global Health","Internal Medicine","Public Health"]
doi:10.7717/peerj.4385
147 downloads
670 views

Objectives We aimed to evaluate the global scientific output of gene research of myocardial infarction and explore their hotspots and frontiers from 2001 to 2015, using bibliometric methods. Methods Articles about the gene research of myocardial infarction between...

["Genetics","Cardiology","Statistics","Medical Genetics"]
doi:10.7717/peerj.4354
85 downloads
717 views

There is growing interest in applying detailed mathematical models of the heart for ion-channel related cardiac toxicity prediction. However, a debate as to whether such complex models are required exists. Here an assessment in the predictive performance between...

["Mathematical Biology","Toxicology","Cardiology","Pharmacology"]
doi:10.7717/peerj.4352
97 downloads
563 views

Background Long non-coding RNAs (lncRNAs) have been reported to modulate cardiovascular diseases, and expression dynamics of lncRNAs in the bloodstream were proposed to be potential biomarkers for clinical diagnosis. However, few cardiovascular diseases-related...

["Molecular Biology","Cardiology","Pathology","Public Health"]
doi:10.7717/peerj.4246
96 downloads
392 views

Background Bedside non-invasive techniques, such as radial artery tonometry, to estimate hemodynamic parameters have gained increased relevance as an attractive alternative and efficient method to measure hemodynamics in outpatient departments. For our pilot study,...

["Cardiology","Drugs and Devices"]
doi:10.7717/peerj.4132
155 downloads
471 views

Background Cardiac stem cells (CSCs) play a vital role in cardiac homeostasis. A decrease in the efficiency of cardiac stem cells is speculated in various cardiac abnormalities. The maintenance of a healthy stem cell population is essential for the prevention of...

["Cell Biology","Cardiology"]
doi:10.7717/peerj.3882
1 citation
152 downloads
524 views

Objective The present study aimed to assess the effects of exercise with dietary restriction on cardiac autonomic activity, arterial stiffness, and cardiovascular biomarkers in obese individuals. Methods Seventeen obese adults completed an 8-week exercise and dietary...

["Developmental Biology","Neuroscience","Cardiology","Clinical Trials"]
doi:10.7717/peerj.3900
86 downloads
399 views

Background Individuals with type 2 diabetes (T2D) are at an increased risk of coronary heart disease (CHD). Diabetic complications have recently been associated with a measure of glucose metabolism known as the hemoglobin glycation index (HGI). Currently there...

["Cardiology","Diabetes and Endocrinology"]
doi:10.7717/peerj.3875
235 downloads
2,218 views

Objective Extracorporeal life support (ECLS) is a life-saving procedure used in the treatment of severe cardiogenic shock. Within this retrospective single centre study, we examined our experience in this critically ill patient cohort to assess outcomes and clinical...

["Cardiology","Clinical Trials","Emergency and Critical Care","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3813
90 downloads
485 views

Background Hypertension and dyssomnia are increasing significantly in Mongolians, and the related factors of ethnic differences in hypertension and dyssomnia between Mongolians and Han Chinese are unclear. This study examined the relationship of morning surge in...

["Cardiology","Global Health","Public Health"]
doi:10.7717/peerj.3758

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