Peer-reviewed Articles

17 downloads
156 views

Toxicity issues and biocompatibility concerns with traditional classical chemical cross-linking processes prevent them from being universal approaches for hydrogel fabrication for tissue engineering. Physical cross-linking methods are non-toxic and widely used...

["Bioengineering","Biotechnology"]
doi:10.7717/peerj.3498
21 downloads
143 views

The Gram-negative bacteria Photorhabdus and Xenorhabdus are known to produce a variety of different natural products (NP). These compounds play different roles since the bacteria live in symbiosis with nematodes and are pathogenic to insect larvae in the soil....

["Biochemistry","Biotechnology","Microbiology","Molecular Biology"]
doi:10.7717/peerj.3471
16 downloads
143 views

Clostridium septicum produces a number of diseases in human and farm animals which, in most of the cases, are fatal without clinical intervention. Alpha toxin is an important agent and the unique lethal virulent factor produced by Clostridium septicum. This toxin...

["Biochemistry","Biotechnology"]
doi:10.7717/peerj.3407
35 downloads
263 views

Background Stem cells are normally isolated from dental pulps using the enzymatic digestion or the outgrowth method. However, the effects of the isolation method on the quality of the isolated stem cells are not studied in detail in murine models. The aim of this...

["Biotechnology","Cell Biology"]
doi:10.7717/peerj.3180
72 downloads
273 views

Characteristics of late maturity in fruit are good agronomic traits for extending the harvest period and marketing time. However, underlying molecular basis of the late-maturing mechanism in fruit is largely unknown. In this study, RNA sequencing (RNA-Seq) technology...

["Agricultural Science","Biotechnology","Molecular Biology","Plant Science"]
doi:10.7717/peerj.3343
58 downloads
252 views

Background Adipose-derived mesenchymal stem cells (ADSCs) have shown great potential in the treatment of various diseases. However, the optimum short-term storage condition of ADSCs in 2∼8 °C is rarely reported. This study aimed at optimizing a short-term storage...

["Biotechnology","Cell Biology","Translational Medicine"]
doi:10.7717/peerj.3301
89 downloads
336 views

Background Cell membrane permeabilization by pulsed electromagnetic fields (PEMF) is a novel contactless method which results in effects similar to conventional electroporation. The non-invasiveness of the methodology, independence from the biological object homogeneity...

["Biochemistry","Biophysics","Biotechnology"]
doi:10.7717/peerj.3267
105 downloads
456 views

Alzheimer’s disease is a multifactorial disorder caused by the interaction of genetic, epigenetic and environmental factors. The formation of cytotoxic oligomers consisting of Aβ peptide is widely accepted as being one of the main key events triggering the development...

["Biophysics","Biotechnology","Cell Biology","Molecular Biology","Neuroscience"]
doi:10.7717/peerj.3086
296 downloads
1,052 views

The human population is growing and, globally, we must meet the challenge of increased protein needs required to feed this population. Single cell proteins (SCP), when coupled to aquaculture production, offer a means to ensure future protein needs can be met without...

["Agricultural Science","Aquaculture, Fisheries and Fish Science","Biotechnology","Food Science and Technology","Microbiology"]
doi:10.7717/peerj.3170
62 downloads
502 views

The filamentous fungus Rhizopus delemar naturally accumulates relatively high amounts of fumarate. Although the culture conditions that increase fumarate yields are well established, the network underlying the accumulation of fumarate is not yet fully understood....

["Biochemistry","Bioinformatics","Biotechnology","Microbiology"]
doi:10.7717/peerj.3133
438 downloads
627 views

Fungal pathogenic attacks are one of the major threats to the growth and productivity of crop plants. Currently, instead of synthetic fungicides, the use of plant growth-promoting bacterial endophytes has been considered intriguingly eco-friendly in nature. Here,...

["Agricultural Science","Biotechnology","Plant Science"]
doi:10.7717/peerj.3107
129 downloads
483 views

Background Sesquiterpenes are 15-carbon terpenes synthesized by sesquiterpene synthases using farnesyl diphosphate (FPP) as a substrate. Recently, a sesquiterpene synthase gene that encodes a 65 kDa protein was isolated from the aromatic plant Persicaria minor....

["Biochemistry","Biotechnology","Molecular Biology"]
doi:10.7717/peerj.2961
136 downloads
419 views

Background Polygonum minus is an herbal plant in the Polygonaceae family which is rich in ethnomedicinal plants. The chemical composition and characteristic pungent fragrance of Polygonum minus have been extensively studied due to its culinary and medicinal properties....

["Bioinformatics","Biotechnology","Genomics"]
doi:10.7717/peerj.2938
108 downloads
505 views

Macrobrachium rosenbergii nodavirus (MrNv) poses a major threat to the prawn industry. Currently, no effective vaccine and treatment are available to prevent the spread of MrNv. Its infection mechanism and localisation in a host cell are also not well characterised....

["Biotechnology","Cell Biology","Microbiology","Molecular Biology","Virology"]
doi:10.7717/peerj.2947
1 citation
84 downloads
427 views

Snakebite envenomings represent a neglected public health issue in many parts of the rural tropical world. Animal-derived antivenoms have existed for more than a hundred years and are effective in neutralizing snake venom toxins when timely administered. However,...

["Bioinformatics","Biotechnology","Toxicology","Immunology","Synthetic Biology"]
doi:10.7717/peerj.2924

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