Peer-reviewed Articles

15 downloads
130 views

The present study first identified the biotransformation of starch as a novel preparation method was investigated using the alpha-transglucosidase-producing Geobacillus stearothermophilus U2. Subsequently, 5 L- and 20 L-scale fermentations were performed. After...

["Biochemistry","Biotechnology","Microbiology"]
doi:10.7717/peerj.5086
16 downloads
137 views

Background Entolimod is a Salmonella enterica flagellin derivate. Previous work has demonstrated that entolimod effectively protects mice and non-human primates from ionizing radiation. However, it caused a “flu-like” syndrome after radioprotective and anticancer...

["Biochemistry","Bioengineering","Biotechnology"]
doi:10.7717/peerj.5043
39 downloads
183 views

Background Ganoderma lucidum, a valuable medicinal fungus, is widely distributed in China. It grows alongside with a complex microbial ecosystem in the substrate. As sequencing technology advances, it is possible to reveal the composition and functions of substrate-associated...

["Agricultural Science","Biodiversity","Biotechnology","Microbiology"]
doi:10.7717/peerj.4975
33 downloads
226 views

L-amino acid oxidases (LAAOs) are ubiquitous enzymes in nature. Bioactivities described for these enzymes include apoptosis induction, edema formation, induction or inhibition of platelet aggregation, as well as antiviral, antiparasite, and antibacterial actions....

["Biochemistry","Biotechnology","Microbiology","Toxicology"]
doi:10.7717/peerj.4924
30 downloads
215 views

Cell quantification assays are essential components of most biological and clinical labs. However, many currently available quantification assays, including flow cytometry and commercial cell counting systems, suffer from unique drawbacks that limit their overall...

["Bioengineering","Biotechnology"]
doi:10.7717/peerj.4937
54 downloads
445 views

Background Carnivorous plants have been fascinating researchers with their unique characters and bioinspired applications. These include medicinal trait of some carnivorous plants with potentials for pharmaceutical industry. Methods This review will cover recent...

["Biochemistry","Biotechnology","Genomics","Plant Science"]
doi:10.7717/peerj.4914
49 downloads
218 views

Plant-specific GRAS transcription factors regulate various biological processes in plant growth, development and stress responses. However, this important gene family was not fully characterized in pepper (Capsicum annuum L.), an economically important vegetable...

["Agricultural Science","Biotechnology"]
doi:10.7717/peerj.4796
34 downloads
209 views

Background The Lepidopteran ambidensovirus 1 isolated from Junonia coenia (hereafter JcDV) is an invertebrate parvovirus considered as a viral transduction vector as well as a potential tool for the biological control of insect pests. Previous works showed that...

["Bioinformatics","Biotechnology","Cell Biology","Virology"]
doi:10.7717/peerj.4860
76 downloads
493 views

Experimental protocols are key when planning, performing and publishing research in many disciplines, especially in relation to the reporting of materials and methods. However, they vary in their content, structure and associated data elements. This article presents...

["Biochemistry","Biotechnology","Cell Biology","Molecular Biology","Plant Science"]
doi:10.7717/peerj.4795
64 downloads
213 views

Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor skin to achieve...

["Bioengineering","Biotechnology","Dermatology"]
doi:10.7717/peerj.4815
63 downloads
183 views

Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals that has caused tremendous economic losses worldwide. In this study, we designed a chimeric nanoparticles (CNPs) vaccine that displays the predominant epitope of the serotype O...

["Bioengineering","Biotechnology","Immunology"]
doi:10.7717/peerj.4823
62 downloads
301 views

Proteins that modify the activity of transcription factors (TFs) are often called modulators and play a vital role in gene transcriptional regulation. Alternative splicing is a critical step of gene processing, and differentially spliced isoforms may have different...

["Bioengineering","Bioinformatics","Biotechnology","Genetics","Computational Science"]
doi:10.7717/peerj.4686
124 downloads
587 views

Hypersaline microbial mats develop through seasonal and diel fluctuations, as well as under several physicochemical variables. Hence, resident microorganisms commonly employ strategies such as the synthesis of polyhydroxyalkanoates (PHAs) in order to resist changing...

["Biotechnology","Ecology","Microbiology"]
doi:10.7717/peerj.4780
79 downloads
556 views

Background Tissue engineering has been shown to exhibit great potential for the creation of biomaterials capable of developing into functional tissues. Cellular expansion and integration depends on the quality and surface-determinant factors of the scaffold, which...

["Bioengineering","Biotechnology","Cell Biology"]
doi:10.7717/peerj.4656
110 downloads
795 views

13C-Metabolic flux analysis (MFA) is a powerful approach to estimate intracellular reaction rates which could be used in strain analysis and design. Processing and analysis of labeling data for calculation of fluxes and associated statistics is an essential part...

["Biochemistry","Biotechnology","Computational Biology"]
doi:10.7717/peerj.4716

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