Peer-reviewed Articles

46 downloads
390 views

Background There is convincing evidence for the benefits of resistance training on vertical jump improvements, but little evidence to guide optimal training prescription. The inability to detect small between modality effects may partially reflect the use of ANOVA...

["Biophysics","Kinesiology"]
doi:10.7717/peerj.4620
63 downloads
331 views

The palm borer moth Paysandisia archon (Castniidae; giant butterfly-moths) has brown dorsal forewings and strikingly orange-coloured dorsal hindwings with white spots surrounded by black margins. Here, we have studied the structure and pigments of the wing scales...

["Biophysics","Entomology"]
doi:10.7717/peerj.4590
86 downloads
603 views

The binding specificity of botulinum neurotoxins (BoNTs) is primarily a consequence of their ability to bind to multiple receptors at the same time. BoNTs consist of three distinct domains, a metalloprotease light chain (LC), a translocation domain (HN) and a receptor-binding...

["Biochemistry","Biophysics","Microbiology"]
doi:10.7717/peerj.4552
58 downloads
527 views

Objective In the foveola of the eye, photoreceptors and Müller cells with a unique morphology have been described, but little is known about their 3D structure and orientation. Considering that there is an angle-dependent change in the foveolar photoreceptor response...

["Biophysics","Cell Biology","Anatomy and Physiology","Ophthalmology","Histology"]
doi:10.7717/peerj.4482
74 downloads
325 views

The structure-thermodynamics correlation analysis was performed for a series of fluorine- and chlorine-substituted benzenesulfonamide inhibitors binding to several human carbonic anhydrase (CA) isoforms. The total of 24 crystal structures of 16 inhibitors bound...

["Biophysics","Drugs and Devices"]
doi:10.7717/peerj.4412
59 downloads
450 views

Osmolytes and macromolecular crowders have the potential to influence the stability of secondary structure motifs and alter preferences for conserved nucleic acid sequences in vivo. To further understand the cellular function of RNA we observed the effects of a...

["Biochemistry","Biophysics"]
doi:10.7717/peerj.4236
127 downloads
568 views

Background N-acetylcarnosine (NAC), a dipeptide with powerful antioxidant properties that is extensively used as a pharmaceutical prodrug for the treatment of cataract and acute gastric disease, was investigated by molecular dynamics with the GROMACS program in...

["Bioengineering","Biophysics","Computational Science"]
doi:10.7717/peerj.4270
77 downloads
321 views

The genome of the chlorarchiniophyte Bigelowiella natans codes for a protein annotated as an α-actinin-like protein. Analysis of the primary sequence indicate that this protein has the same domain structure as other α-actinins, a N-terminal actin-binding domain...

["Biochemistry","Biophysics","Developmental Biology"]
doi:10.7717/peerj.4288
107 downloads
575 views

Coarse-grained (CG) models have been successful in simulating the chemical properties of lipid bilayers, but accurate treatment of membrane proteins and lipid-protein molecular interactions remains a challenge. The CgProt force field, original developed with the...

["Biophysics","Computational Biology","Computational Science"]
doi:10.7717/peerj.4230
136 downloads
571 views

Mushrooms are recognized as one of the main contributors to internal radiation exposure from the activity concentration of radiocesium released by the accident at the Chernobyl nuclear power plant (CNNP). We evaluated the activity concentrations of the artificial...

["Biochemistry","Biophysics","Environmental Sciences","Mycology","Public Health"]
doi:10.7717/peerj.4222
101 downloads
929 views

A frequency ratio of about 1.06 often appears in cochlear mechanics, and the question naturally arises, why? The ratio is close to that of the semitone (1.059) in music, giving reason to think that this aspect of musical perception might have a cochlear basis....

["Biophysics","Neuroscience","Anatomy and Physiology","Otorhinolaryngology"]
doi:10.7717/peerj.4192
68 downloads
354 views

The microtubule depolymerising kinesin-13, MCAK, is phosphorylated at residue T537 by Cdk1. This is the only known phosphorylation site within MCAK’s motor domain. To understand the impact of phosphorylation by Cdk1 on microtubule depolymerisation activity, we...

["Biochemistry","Biophysics","Molecular Biology"]
doi:10.7717/peerj.4034
243 downloads
900 views

The expression of carbonic anhydrase (CA) IX is up-regulated in many types of solid tumors in humans under hypoxic and acidic microenvironment. Inhibition of CA IX enzymatic activity with selective inhibitors, antibodies or labeled probes has been shown to reverse...

["Biochemistry","Biophysics","Drugs and Devices"]
doi:10.7717/peerj.4068
150 downloads
1,177 views

In this paper, we have presented a microwave scattering analysis from multiple human head models. This study incorporates different levels of detail in the human head models and its effect on microwave scattering phenomenon. Two levels of detail are taken into...

["Bioengineering","Biophysics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.4061
1 citation
169 downloads
935 views

Zebrafish is emerging as a species of choice for the study of a number of biomechanics problems, including balance development, schooling, and neuromuscular transmission. The precise quantification of the flow physics around swimming zebrafish is critical toward...

["Animal Behavior","Aquaculture, Fisheries and Fish Science","Bioengineering","Biophysics","Freshwater Biology"]
doi:10.7717/peerj.4041

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