Peer-reviewed Articles

19 downloads
268 views

Osmolytes and macromolecular crowders have the potential to influence the stability of secondary structure motifs and alter preferences for conserved nucleic acid sequences in vivo. To further understand the cellular function of RNA we observed the effects of a...

["Biochemistry","Biophysics"]
doi:10.7717/peerj.4236
44 downloads
276 views

Background N-acetylcarnosine (NAC), a dipeptide with powerful antioxidant properties that is extensively used as a pharmaceutical prodrug for the treatment of cataract and acute gastric disease, was investigated by molecular dynamics with the GROMACS program in...

["Bioengineering","Biophysics","Computational Science"]
doi:10.7717/peerj.4270
55 downloads
229 views

The genome of the chlorarchiniophyte Bigelowiella natans codes for a protein annotated as an α-actinin-like protein. Analysis of the primary sequence indicate that this protein has the same domain structure as other α-actinins, a N-terminal actin-binding domain...

["Biochemistry","Biophysics","Developmental Biology"]
doi:10.7717/peerj.4288
65 downloads
393 views

Coarse-grained (CG) models have been successful in simulating the chemical properties of lipid bilayers, but accurate treatment of membrane proteins and lipid-protein molecular interactions remains a challenge. The CgProt force field, original developed with the...

["Biophysics","Computational Biology","Computational Science"]
doi:10.7717/peerj.4230
79 downloads
418 views

Mushrooms are recognized as one of the main contributors to internal radiation exposure from the activity concentration of radiocesium released by the accident at the Chernobyl nuclear power plant (CNNP). We evaluated the activity concentrations of the artificial...

["Biochemistry","Biophysics","Environmental Sciences","Mycology","Public Health"]
doi:10.7717/peerj.4222
81 downloads
805 views

A frequency ratio of about 1.06 often appears in cochlear mechanics, and the question naturally arises, why? The ratio is close to that of the semitone (1.059) in music, giving reason to think that this aspect of musical perception might have a cochlear basis....

["Biophysics","Neuroscience","Anatomy and Physiology","Otorhinolaryngology"]
doi:10.7717/peerj.4192
51 downloads
282 views

The microtubule depolymerising kinesin-13, MCAK, is phosphorylated at residue T537 by Cdk1. This is the only known phosphorylation site within MCAK’s motor domain. To understand the impact of phosphorylation by Cdk1 on microtubule depolymerisation activity, we...

["Biochemistry","Biophysics","Molecular Biology"]
doi:10.7717/peerj.4034
151 downloads
740 views

The expression of carbonic anhydrase (CA) IX is up-regulated in many types of solid tumors in humans under hypoxic and acidic microenvironment. Inhibition of CA IX enzymatic activity with selective inhibitors, antibodies or labeled probes has been shown to reverse...

["Biochemistry","Biophysics","Drugs and Devices"]
doi:10.7717/peerj.4068
107 downloads
993 views

In this paper, we have presented a microwave scattering analysis from multiple human head models. This study incorporates different levels of detail in the human head models and its effect on microwave scattering phenomenon. Two levels of detail are taken into...

["Bioengineering","Biophysics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.4061
1 citation
122 downloads
727 views

Zebrafish is emerging as a species of choice for the study of a number of biomechanics problems, including balance development, schooling, and neuromuscular transmission. The precise quantification of the flow physics around swimming zebrafish is critical toward...

["Animal Behavior","Aquaculture, Fisheries and Fish Science","Bioengineering","Biophysics","Freshwater Biology"]
doi:10.7717/peerj.4041
137 downloads
517 views

Solanum lycopersicum, belonging to Solanaceae, is one of the commonly used model plants. The GRAS genes are transcriptional regulators, which play a significant role in plant growth and development, and the functions of several GRAS genes have been recognized,...

["Agricultural Science","Biophysics","Genomics"]
doi:10.7717/peerj.3955
154 downloads
889 views

Neuron types (e.g., pyramidal cells) within one area of the brain are often considered homogeneous, despite variability in their biophysical properties. Here we review literature demonstrating variability in the electrical activity of CA1 hippocampal pyramidal...

["Biophysics","Neuroscience"]
doi:10.7717/peerj.3836
105 downloads
980 views

Energy buffering systems are key for homeostasis during variations in energy supply. Spiders are the most important predators for insects and therefore key in terrestrial ecosystems. From biomedical interest, spiders are important for their venoms and as a source...

["Biochemistry","Biophysics","Zoology","Allergy and Clinical Immunology"]
doi:10.7717/peerj.3787
188 downloads
1,403 views

Background The ostrich is a cursorial bird with extraordinary speed and endurance, especially in the desert, and thus is an ideal large-scale animal model for mechanic study of locomotion on granular substrate. Methods The plantar pressure distributions of ostriches...

["Animal Behavior","Bioengineering","Biophysics"]
doi:10.7717/peerj.3613
218 downloads
760 views

Background The growth and development of plants is deleteriously affected by various biotic and abiotic stress factors. Wounding in plants is caused by exposure to environmental stress, mechanical stress, and via herbivory. Typically, oxidative burst in response...

["Agricultural Science","Biophysics","Environmental Impacts","Environmental Sciences","Plant Science"]
doi:10.7717/peerj.3050

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