Peer-reviewed Articles

100 downloads
543 views

Segmentation of histopathology sections is a necessary preprocessing step for digital pathology. Due to the large variability of biological tissue, machine learning techniques have shown superior performance over conventional image processing methods. Here we present...

["Bioengineering","Oncology","Radiology and Medical Imaging","Histology","Computational Science"]
doi:10.7717/peerj.3874
57 downloads
680 views

Background Locomotion results from the generation of ground reaction forces (GRF) that cause translations of the center of mass (COM) and generate moments that rotate the body around the COM. The trot is a diagonally-synchronized gait performed by horses at intermediate...

["Animal Behavior","Bioengineering","Veterinary Medicine","Zoology","Kinesiology"]
doi:10.7717/peerj.3866
118 downloads
661 views

The mammalian jaw is often modelled as a third-class lever for the purposes of biomechanical analyses, owing to the position of the resultant muscle force between the jaw joint and the teeth. However, it has been proposed that in some rodents the jaws operate as...

["Bioengineering","Evolutionary Studies","Zoology"]
doi:10.7717/peerj.3741
1 citation
65 downloads
348 views

Objective The trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might be a viable therapeutic approach. Decellularized TM scaffolds have previously been produced...

["Bioengineering","Biotechnology","Ophthalmology"]
doi:10.7717/peerj.3629
102 downloads
618 views

This article describes a public data set containing the three-dimensional kinematics of the whole human body and the ground reaction forces (with a dual force platform setup) of subjects who were standing still for 60 s in different conditions, in which the subjects’...

["Bioengineering","Neuroscience","Kinesiology"]
doi:10.7717/peerj.3626
144 downloads
998 views

Background The ostrich is a cursorial bird with extraordinary speed and endurance, especially in the desert, and thus is an ideal large-scale animal model for mechanic study of locomotion on granular substrate. Methods The plantar pressure distributions of ostriches...

["Animal Behavior","Bioengineering","Biophysics"]
doi:10.7717/peerj.3613
119 downloads
438 views

Introduction Different types of headaches and TMJ click influence the masseter muscle activity. The aim of this study was to assess the trend of energy level of the electromyography (EMG) activity of the masseter muscle during open-close clench cycles in migraine...

["Bioengineering","Computational Biology","Evidence Based Medicine","Radiology and Medical Imaging","Translational Medicine"]
doi:10.7717/peerj.3556
72 downloads
524 views

Cleavage of mRNA molecules causes their rapid degradation, thereby playing an important role in regulation of gene expression and host genome defense from viruses and transposons in bacterial and eukaryotic cells. Current negative-readout, and repressor-based positive-readout...

["Bioengineering","Molecular Biology","Synthetic Biology"]
doi:10.7717/peerj.3602
112 downloads
406 views

Transpedicular transdiscal screw fixation is an alternative technique used in lumbar spine fixation; however, it requires an accurate screw trajectory. The aim of this study is to design a novel 3D-printed custom drill guide and investigate its accuracy to guide...

["Bioengineering","Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.3564
53 downloads
672 views

CodonGenie, freely available from http://codon.synbiochem.co.uk, is a simple web application for designing ambiguous codons to support protein mutagenesis applications. Ambiguous codons are derived from specific heterogeneous nucleotide mixtures, which create sequence...

["Bioengineering","Bioinformatics","Biotechnology","Computational Biology","Synthetic Biology"]
doi:10.7717/peerj-cs.120
82 downloads
390 views

Background Osteoprotegerin (OPG) is used for the systemic treatment of bone diseases, although it has many side effects. The aim of this study was to investigate a newly formulated OPG-chitosan gel for local application to repair bone defects. Recent studies have...

["Bioengineering","Orthopedics","Pharmacology"]
doi:10.7717/peerj.3513
118 downloads
443 views

Artifacts removal and rhythms extraction from electroencephalography (EEG) signals are important for portable and wearable EEG recording devices. Incorporating a novel grouping rule, we proposed an adaptive singular spectrum analysis (SSA) method for artifacts...

["Bioengineering","Computational Biology","Neuroscience"]
doi:10.7717/peerj.3474
185 downloads
691 views

Toxicity issues and biocompatibility concerns with traditional classical chemical cross-linking processes prevent them from being universal approaches for hydrogel fabrication for tissue engineering. Physical cross-linking methods are non-toxic and widely used...

["Bioengineering","Biotechnology"]
doi:10.7717/peerj.3498
131 downloads
864 views

This paper uses X-ray computed tomography to track the mechanical response of a vertebrate (Barnacle goose) long bone subjected to an axial compressive load, which is increased gradually until failure. A loading rig was mounted in an X-ray computed tomography system...

["Bioengineering","Kinesiology","Orthopedics","Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.3416
1 citation
451 downloads
2,205 views

Background The goals of this study were (1) to present the set of data evaluating running biomechanics (kinematics and kinetics), including data on running habits, demographics, and levels of muscle strength and flexibility made available at Figshare (DOI: 10.6084/m9.figshare.4543435);...

["Bioengineering","Neuroscience","Kinesiology","Computational Science"]
doi:10.7717/peerj.3298

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