Peer-reviewed Articles

29 downloads
164 views

The wood frog (Rana sylvatica) can endure freezing of up to 65% of total body water during winter. When frozen, wood frogs enter a dormant state characterized by a cessation of vital functions (i.e., no heartbeat, blood circulation, breathing, brain activity, or...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.4014
26 downloads
234 views

Robotic labs, in which experiments are carried out entirely by robots, have the potential to provide a reproducible and transparent foundation for performing basic biomedical laboratory experiments. In this article, we investigate whether these labs could be applicable...

["Biochemistry","Science Policy","Computational Science"]
doi:10.7717/peerj.3997
56 downloads
299 views

Background Deficiency of available forms of phosphorus is common in most soils and causes reduction of crop plants growth and yield. Recently, model plants responses to phosphate (Pi) deficiency have been intensively studied. However, acclimation mechanisms of...

["Agricultural Science","Biochemistry","Environmental Sciences","Plant Science","Soil Science"]
doi:10.7717/peerj.3989
101 downloads
403 views

Clinical evidence points to neuroprotective effects of smoking in Parkinson’s disease (PD), but the molecular mechanisms remain unclear. We investigated the pharmacological pathways involved in these neuroprotective effects, which could provide novel ideas for...

["Biochemistry","Molecular Biology","Neuroscience","Neurology","Pharmacology"]
doi:10.7717/peerj.3933
104 downloads
318 views

Increased levels of long noncoding RNA H19 (H19) have been observed in many inflammatory and organ fibrosis diseases including ulcerative colitis, osteoarthritis, liver fibrosis, renal fibrosis and pulmonary fibrosis. However, the role of H19 in bovine mastitis...

["Biochemistry","Cell Biology","Veterinary Medicine"]
doi:10.7717/peerj.3950
68 downloads
540 views

In the context of a hunt for a postulated hormone that is tissue-mass inhibiting and reproductively associated, there is described probable relatedness to a granin protein. A 7–8 kDa polypeptide candidate (gels/MS) appeared in a bioassay-guided fractionation campaign...

["Biochemistry","Cell Biology","Diabetes and Endocrinology","Neurology"]
doi:10.7717/peerj.3833
79 downloads
231 views

Background Aspergillus niger, along with many other lignocellulolytic fungi, has been widely used as a commercial workhorse for cellulase production. A fungal cellulase system generally includes three major classes of enzymes i.e., β-glucosidases, endoglucanases...

["Biochemistry","Biotechnology","Molecular Biology"]
doi:10.7717/peerj.3909
69 downloads
461 views

Italian ryegrass (Lolium multiflorum) is an important cool-season, annual forage crop for the grassland rotation system in Southern China. The primary aim of breeding programs is always to seek to improve forage quality in the animal productivity system; however,...

["Agricultural Science","Biochemistry","Plant Science","Statistics"]
doi:10.7717/peerj.3867
101 downloads
420 views

Rapid proliferation and Warburg effect make cancer cells consume plenty of glucose, which induces a low glucose micro-environment within the tumor. Up to date, how cancer cells keep proliferating in the condition of glucose insufficiency still remains to be explored....

["Biochemistry","Cell Biology","Oncology"]
doi:10.7717/peerj.3804
93 downloads
301 views

Background Food selection and ingestion both in humans and rodents, often is a critical factor in determining excess energy intake and its related disorders. Methods Two different concepts of high-fat diets were tested for their obesogenic effects in rats; in both...

["Biochemistry","Nutrition","Metabolic Sciences"]
doi:10.7717/peerj.3697
76 downloads
580 views

Energy buffering systems are key for homeostasis during variations in energy supply. Spiders are the most important predators for insects and therefore key in terrestrial ecosystems. From biomedical interest, spiders are important for their venoms and as a source...

["Biochemistry","Biophysics","Zoology","Allergy and Clinical Immunology"]
doi:10.7717/peerj.3787
169 downloads
595 views

In recent years, the use of lectins for screening of potential biomarkers has gained increased importance in cancer research, given the development in glycobiology that highlights altered structural changes of glycans in cancer associated processes. Lectins, having...

["Biochemistry","Biotechnology","Oncology"]
doi:10.7717/peerj.3784
110 downloads
519 views

Conserved homologues of the Hrd1 ubiquitin ligase target for degradation proteins that persistently or aberrantly engage the endoplasmic reticulum translocon, including mammalian apolipoprotein B (apoB; the major protein component of low-density lipoproteins) and...

["Biochemistry","Cell Biology","Genetics","Molecular Biology"]
doi:10.7717/peerj.3728
74 downloads
520 views

The variability in zooplankton fatty acid composition may be an indicator of larval fish habitat quality as fatty acids are linked to fish larval growth and survival. We sampled an anadromous fish nursery, the Chowan River, during spring of 2013 in order to determine...

["Aquaculture, Fisheries and Fish Science","Biochemistry","Zoology","Freshwater Biology"]
doi:10.7717/peerj.3667
124 downloads
492 views

Carbon nanotubes (CNTs) have a broad range of applications and are generally considered human-engineered nanomaterials. However, carbon nanostructures have been found in ice cores and oil wells, suggesting that nature may provide appropriate conditions for CNT...

["Biochemistry","Ecology","Ecosystem Science","Soil Science","Synthetic Biology"]
doi:10.7717/peerj.3658

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