Peer-reviewed Articles

34 downloads
414 views

Background Bumblebees (Hymenoptera: Apidae: Bombus) are well known for their important inter- and intra-specific variation in hair (or pubescence) color patterns, but the chemical nature of the pigments associated with these patterns is not fully understood. For...

["Biochemistry","Entomology","Evolutionary Studies","Zoology"]
doi:10.7717/peerj.3300
12 downloads
153 views

Biomarkers are the measurable changes associated with a physiological or pathophysiological process. The content of urine frequently changes because it is not controlled by homeostatic mechanisms, and these alterations can be a source of biomarkers. However, urine...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.3350
28 downloads
119 views

Coptis chinensis Franch., the Chinese goldthread (‘Weilian’ in Chinese), one of the most important medicinal plants from the family Ranunculaceae, and its rhizome has been widely used in Traditional Chinese Medicine for centuries. Here, we analyzed the chemical...

["Biochemistry","Bioinformatics","Computational Biology","Plant Science"]
doi:10.7717/peerj.3303
54 downloads
346 views

Background Obesity has become a worldwide burden to public health in recent decades. Given that obesity is caused by an imbalance between caloric intake and expenditure, and that dietary fat is the most important energy source of all macronutrients (by providing...

["Biochemistry","Food Science and Technology","Diabetes and Endocrinology","Nutrition"]
doi:10.7717/peerj.3279
43 downloads
185 views

Tuberculosis is one of the world’s deadliest infectious disease with 1.5 millions deaths annually. It is imperative to discover novel compounds with potent activity against M. tuberculosis. In this study, susceptibilities of M. smegmatis to the octahedral ruthenium(II)...

["Biochemistry","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3252
59 downloads
484 views

Mayaro virus (MAYV) is an emergent sylvatic alphavirus in South America, related to sporadic outbreaks of a chikungunya-like human febrile illness accompanied by severe arthralgia. Despite its high potential for urban emergence, MAYV is still an obscure virus with...

["Biochemistry","Microbiology","Virology","Infectious Diseases"]
doi:10.7717/peerj.3245
37 downloads
106 views

Background Snakes belonging to the Bothrops genus are vastly distributed in Central and South America and are responsible for most cases of reported snake bites in Latin America. The clinical manifestations of the envenomation caused by this genus are due to three...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.3203
63 downloads
275 views

Background Cell membrane permeabilization by pulsed electromagnetic fields (PEMF) is a novel contactless method which results in effects similar to conventional electroporation. The non-invasiveness of the methodology, independence from the biological object homogeneity...

["Biochemistry","Biophysics","Biotechnology"]
doi:10.7717/peerj.3267
105 downloads
994 views

We report the genome sequence of Exiguobacterium chiriqhucha str. N139, isolated from a high-altitude Andean lake. Comparative genomic analyses of the Exiguobacterium genomes available suggest that our strain belongs to the same species as the previously reported...

["Biochemistry","Biodiversity","Bioinformatics","Genomics","Microbiology"]
doi:10.7717/peerj.3162
54 downloads
342 views

Metals are present in aquatic environments as a result of natural and anthropogenic inputs, and may induce toxicity to organisms. One of the main factors that influence this toxicity in fresh water is natural organic matter (NOM) but all NOMs are not the same in...

["Biochemistry","Environmental Sciences","Marine Biology","Toxicology"]
doi:10.7717/peerj.3141
120 downloads
472 views

The Clustered Regularly Interspaced Short Palindromic Repeats associated (CRISPR-Cas) systems consist of RNA-protein complexes that provide bacteria and archaea with sequence-specific immunity against bacteriophages, plasmids, and other mobile genetic elements....

["Biochemistry","Bioinformatics","Evolutionary Studies","Microbiology"]
doi:10.7717/peerj.3161
1 citation
79 downloads
348 views

Background ABO blood group is a hereditary factor of plasma levels of coagulation factor VIII (FVIII) and von Willebrand factor (VWF). Age and gender have been shown to influence FVIII, VWF, fibrinogen (Fbg), and ADAMTS13 (A disintegrin and metalloprotease with...

["Biochemistry","Global Health","Hematology","Translational Medicine"]
doi:10.7717/peerj.3156
56 downloads
435 views

The filamentous fungus Rhizopus delemar naturally accumulates relatively high amounts of fumarate. Although the culture conditions that increase fumarate yields are well established, the network underlying the accumulation of fumarate is not yet fully understood....

["Biochemistry","Bioinformatics","Biotechnology","Microbiology"]
doi:10.7717/peerj.3133
75 downloads
422 views

Background Deficiencies in lysosomal a-mannosidase (LAM) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey...

["Biochemistry","Developmental Biology","Molecular Biology","Toxicology"]
doi:10.7717/peerj.3109
143 downloads
739 views

Hydrolysis of ATP by Na+/K+-ATPase, a P-Type ATPase, catalyzing active Na+ and K+ transport through cellular membranes leads transiently to a phosphorylation of its catalytical α-subunit. Surprisingly, three-dimensional molecular structure analysis of P-type ATPases...

["Biochemistry","Bioinformatics","Biophysics","Computational Biology","Computational Science"]
doi:10.7717/peerj.3087

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