Peer-reviewed Articles - Medicine

54 downloads
141 views

Background Diabetic kidney disease is the most common cause of chronic kidney disease (CKD). An early event in diabetic kidney disease is alteration of the glomerular basement membrane and the mesangial expansion. Matrix metalloproteinases (MMP) are a family of...

["Biochemistry","Diabetes and Endocrinology","Urology"]
doi:10.7717/peerj.6067
70 downloads
330 views

Background Urothelial carcinoma (UC) is the fifth most common malignancy that accounts for 5% of all cancers. Diagnostic markers that predict UC progressions are inadequate. NF-κB contributes towards disease progression upon constitutive activation in many solid...

["Bioinformatics","Pathology","Urology"]
doi:10.7717/peerj.5563
70 downloads
713 views

Introduction In this study, a survey was prepared for urologists that asked about their primary choice of treatment for urolithiasis in daily practice and their answers were evaluated. Methods The survey was prepared on the Google Docs website and it was sent to...

["Urology","Human-Computer Interaction"]
doi:10.7717/peerj.5390
71 downloads
597 views

Background The purpose of this study was to investigate the relationship between chronic periodontitis (CP) and upper urinary tract stone (UUTS) in Taiwan by using a population-based data set. Methods A total of 16,292 CP patients and 48,876 randomly-selected controls...

["Dentistry","Epidemiology","Public Health","Urology"]
doi:10.7717/peerj.5287
2 citations
202 downloads
650 views

Background Long non-coding RNAs (lncRNAs) play crucial roles in the initiation and progression of renal cell carcinoma (RCC) by competing in binding to miRNAs, and related competitive endogenous RNA (ceRNA) networks have been constructed in several cancers. However,...

["Bioinformatics","Oncology","Urology"]
doi:10.7717/peerj.5124
2 citations
103 downloads
507 views

Background Solute-linked carrier 26 gene family 6 (SLC26A6), which is mainly expressed in intestines and kidneys, is a multifunctional anion transporter crucial in the transport of oxalate anions. This study aimed to investigate the role of kidney SLC26A6 in urolithiasis....

["Biotechnology","Molecular Biology","Urology"]
doi:10.7717/peerj.5192
102 downloads
491 views

Introduction Ureteropelvic junction obstruction (UPJO) is a common congenital anomaly leading to varying degrees of hydronephrosis (HN), ranging from no apparent effect on the renal function to atrophy. Evaluation of these children is based on Diuretic Renal Scintigraphy...

["Nephrology","Pediatrics","Radiology and Medical Imaging","Urology"]
doi:10.7717/peerj.4791
2 citations
207 downloads
818 views

Background The purpose of this study was to evaluate the efficacy of a smartphone-based reminder system in promoting pelvic floor muscle training (PFMT) to help postpartum women manage urinary incontinence (UI). Methods Forty-nine and 212 postpartum women in the...

["Gynecology and Obstetrics","Nursing","Urology","Women\u2019s Health"]
doi:10.7717/peerj.4372
2 citations
152 downloads
810 views

Tumor-infiltrating lymphocytes (TILs) are associated with better clinical outcomes in many tumors. TILs represent a cell-mediated immune response against the carcinoma. CD8+ TILs are a crucial component of cell-mediated immunity. The significance of CD8+ TILs has...

["Immunology","Oncology","Urology"]
doi:10.7717/peerj.3921
1 citation
310 downloads
1,135 views

Background This study was performed to compare changes in urinary incontinence (UI) symptoms and pelvic floor structure during pregnancy between nulliparous and multiparous women. Methods A cross-sectional survey was performed among pregnant women from July 2016...

["Gynecology and Obstetrics","Nursing","Urology","Women's Health"]
doi:10.7717/peerj.3615
3 citations
267 downloads
873 views

Objective To compare the risk of postoperative ureteral stricture formation following retroperitoneal laparoscopic ureterolithotomy (RPLU) and ureteroscopy with holmium: YAG laser lithotripsy (URSL) in patients with proximal ureteral stones. Materials and Methods...

["Nephrology","Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.3483
4 citations
288 downloads
1,003 views

Purpose To assess the overall quality of published urological meta-analyses and identify predictive factors for high quality. Materials and Methods We systematically searched PubMed to identify meta-analyses published from January 1st, 2011 to December 31st, 2015...

["Epidemiology","Evidence Based Medicine","Urology"]
doi:10.7717/peerj.3129
14 citations
4,067 downloads
19,008 views

Importance Case reports describe persistent erectile dysfunction (PED) associated with exposure to 5α-reductase inhibitors (5α-RIs). Clinical trial reports and the manufacturers’ full prescribing information (FPI) for finasteride and dutasteride state that risk...

["Dermatology","Epidemiology","Internal Medicine","Pharmacology","Urology"]
doi:10.7717/peerj.3020
4 citations
1,019 downloads
1,290 views

Background Although the relationship between a history of kidney stones and chronic kidney disease (CKD) has been explored in many studies, it is still far from being well understood. Thus, we conducted a meta-analysis of studies comparing rates of CKD in patients...

["Epidemiology","Nephrology","Urology"]
doi:10.7717/peerj.2907
6 citations
262 downloads
1,194 views

Purpose To clarify the outcome of flexible ureteroscopy (fURS) for management of renal calculi without preoperative stenting. Methods A total of 171 patients who received 176 fURS procedures for unilateral renal stones were reviewed. All procedures were divided...

["Urology"]
doi:10.7717/peerj.2728

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