Peer-reviewed Articles - Medicine

37 downloads
174 views

Leaves from three varieties of Ficus deltoidea, colloquially termed small- (FDS), medium- (FDM), and big-type leaf (FDB), were subjected to water extraction. The crude extracts were fractionated using water (WF) and ethyl acetate (EAF). The phenolic and flavonoid...

["Biochemistry","Cell Biology","Food Science and Technology","Plant Science","Translational Medicine"]
doi:10.7717/peerj.5694
53 downloads
248 views

Objective The benefits of IL-35 treatment have been verified in multiple animal models of diseases, while its influence on T cells immunity under normal condition still needs to be elucidated. The present study was designed to investigate the effects modulating...

["Immunology","Translational Medicine"]
doi:10.7717/peerj.5638
59 downloads
300 views

Background High myopia is a common ocular disease worldwide. To expand our current understanding of the genetic basis of high myopia, we carried out a whole exome sequencing (WES) study to identify potential causal gene mutations. Methods A total of 20 individuals...

["Bioinformatics","Computational Biology","Genetics","Genomics","Translational Medicine"]
doi:10.7717/peerj.5552
59 downloads
279 views

Background Growth arrest and DNA-damage-inducible protein 45 alpha (GADD45A) was previously found to be associated with risk of several kinds of human tumors. Here, we studied the expression and clinical significance of GADD45A in breast cancer. Methods We performed...

["Oncology","Translational Medicine"]
doi:10.7717/peerj.5344
113 downloads
715 views

Background When suffering from chronic pain, attempts to control or avoid pain often compete with other daily activities. Engaging in one activity excludes engaging in another, equally valued activity, which is referred to as “goal conflict.” As yet, the presence...

["Anesthesiology and Pain Management","Psychiatry and Psychology","Public Health","Translational Medicine"]
doi:10.7717/peerj.5272
128 downloads
1,051 views

Background Antibiotic-associated gastrointestinal signs (AAGS) occur commonly in cats. Co-administration of synbiotics is associated with decreased AAGS in people, potentially due to stabilization of the fecal microbiome and metabolome. The purpose of this double-blinded...

["Microbiology","Veterinary Medicine","Gastroenterology and Hepatology","Internal Medicine","Translational Medicine"]
doi:10.7717/peerj.5130
100 downloads
498 views

Background It is possible that physical education professionals, especially those who participate in aerobic activities, have predisposing factors, signs and symptoms of overreaching (OVR) and overtraining (OVT) due to a high load and volume of exercise followed...

["Anatomy and Physiology","Global Health","Kinesiology","Translational Medicine"]
doi:10.7717/peerj.4994
103 downloads
454 views

Background The highly valued medicinal tiger milk mushroom (also known as Lignosus rhinocerus) has the ability to cure numerous ailments. Its anticancer activities are well explored, and recently a partially purified cytotoxic protein fraction termed F5 from the...

["Biochemistry","Genetics","Oncology","Translational Medicine","Data Mining and Machine Learning"]
doi:10.7717/peerj.4940
150 downloads
1,204 views

Background Fecal Microbiota Transplantation (FMT) is an innovative means of treating recurrent Clostridium difficile infection (rCDI), through restoration of gut floral balance. However, there is a lack of data concerning the efficacy of FMT and its impact on the...

["Microbiology","Gastroenterology and Hepatology","Infectious Diseases","Pediatrics","Translational Medicine"]
doi:10.7717/peerj.4663
88 downloads
418 views

Background Antibiotic misuse in the community contributes to antimicrobial resistance. One way to address this may be by better utilizing community pharmacists’ skills in antibiotic prescribing. The aims of this study were to examine the level of support for “down-scheduling”...

["Health Policy","Translational Medicine"]
doi:10.7717/peerj.4726
142 downloads
660 views

Background We established a glioma biobank at Beijing Tiantan Hospital in November, 2010. Specialized residents have been trained to collect, store and manage the biobank in accordance with standard operating procedures. Methods One hundred samples were selected...

["Neurology","Oncology","Translational Medicine"]
doi:10.7717/peerj.4450
167 downloads
864 views

Background Patellofemoral pain (PFP) is often reported as a diffuse pain at the front of the knee during knee-loading activities. A patient’s description of pain location and distribution is commonly drawn on paper by clinicians, which is difficult to quantify,...

["Anesthesiology and Pain Management","Anatomy and Physiology","Orthopedics","Translational Medicine","Human\u2013Computer Interaction"]
doi:10.7717/peerj.4406
133 downloads
783 views

Background Glyburide (also known as glibenclamide) is effective in reducing the severity of tissue destruction and improving functional outcome after experimental spinal cord injury in rodents and so has promise as a therapy in humans. There are many important...

["Veterinary Medicine","Pharmacology","Translational Medicine"]
doi:10.7717/peerj.4387
1 citation
158 downloads
1,185 views

Liver fibrosis is a disease that causes high morbidity and has become a major health problem. Liver fibrosis can lead to the end stage of liver diseases (livercirrhosisand hepatocellularcarcinoma). Currently, liver transplantation is the only effective treatment...

["Cell Biology","Gastroenterology and Hepatology","Translational Medicine"]
doi:10.7717/peerj.4336
2 citations
288 downloads
1,497 views

Background Salvia officinalis (sage) is a native plant to the Mediterranean region and has been used for a long time in traditional medicine for various diseases. We investigated possible anti-diabetic, anti-inflammatory and anti-obesity effects of sage methanol...

["Diabetes and Endocrinology","Nutrition","Translational Medicine"]
doi:10.7717/peerj.4166

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