Peer-reviewed Articles - Medicine

29 downloads
151 views

Background Growth arrest and DNA-damage-inducible protein 45 alpha (GADD45A) was previously found to be associated with risk of several kinds of human tumors. Here, we studied the expression and clinical significance of GADD45A in breast cancer. Methods We performed...

["Oncology","Translational Medicine"]
doi:10.7717/peerj.5344
35 downloads
516 views

Background When suffering from chronic pain, attempts to control or avoid pain often compete with other daily activities. Engaging in one activity excludes engaging in another, equally valued activity, which is referred to as “goal conflict.” As yet, the presence...

["Anesthesiology and Pain Management","Psychiatry and Psychology","Public Health","Translational Medicine"]
doi:10.7717/peerj.5272
97 downloads
896 views

Background Antibiotic-associated gastrointestinal signs (AAGS) occur commonly in cats. Co-administration of synbiotics is associated with decreased AAGS in people, potentially due to stabilization of the fecal microbiome and metabolome. The purpose of this double-blinded...

["Microbiology","Veterinary Medicine","Gastroenterology and Hepatology","Internal Medicine","Translational Medicine"]
doi:10.7717/peerj.5130
78 downloads
364 views

Background It is possible that physical education professionals, especially those who participate in aerobic activities, have predisposing factors, signs and symptoms of overreaching (OVR) and overtraining (OVT) due to a high load and volume of exercise followed...

["Anatomy and Physiology","Global Health","Kinesiology","Translational Medicine"]
doi:10.7717/peerj.4994
75 downloads
362 views

Background The highly valued medicinal tiger milk mushroom (also known as Lignosus rhinocerus) has the ability to cure numerous ailments. Its anticancer activities are well explored, and recently a partially purified cytotoxic protein fraction termed F5 from the...

["Biochemistry","Genetics","Oncology","Translational Medicine","Data Mining and Machine Learning"]
doi:10.7717/peerj.4940
104 downloads
1,030 views

Background Fecal Microbiota Transplantation (FMT) is an innovative means of treating recurrent Clostridium difficile infection (rCDI), through restoration of gut floral balance. However, there is a lack of data concerning the efficacy of FMT and its impact on the...

["Microbiology","Gastroenterology and Hepatology","Infectious Diseases","Pediatrics","Translational Medicine"]
doi:10.7717/peerj.4663
71 downloads
354 views

Background Antibiotic misuse in the community contributes to antimicrobial resistance. One way to address this may be by better utilizing community pharmacists’ skills in antibiotic prescribing. The aims of this study were to examine the level of support for “down-scheduling”...

["Health Policy","Translational Medicine"]
doi:10.7717/peerj.4726
111 downloads
574 views

Background We established a glioma biobank at Beijing Tiantan Hospital in November, 2010. Specialized residents have been trained to collect, store and manage the biobank in accordance with standard operating procedures. Methods One hundred samples were selected...

["Neurology","Oncology","Translational Medicine"]
doi:10.7717/peerj.4450
139 downloads
779 views

Background Patellofemoral pain (PFP) is often reported as a diffuse pain at the front of the knee during knee-loading activities. A patient’s description of pain location and distribution is commonly drawn on paper by clinicians, which is difficult to quantify,...

["Anesthesiology and Pain Management","Anatomy and Physiology","Orthopedics","Translational Medicine","Human\u2013Computer Interaction"]
doi:10.7717/peerj.4406
115 downloads
707 views

Background Glyburide (also known as glibenclamide) is effective in reducing the severity of tissue destruction and improving functional outcome after experimental spinal cord injury in rodents and so has promise as a therapy in humans. There are many important...

["Veterinary Medicine","Pharmacology","Translational Medicine"]
doi:10.7717/peerj.4387
1 citation
136 downloads
1,057 views

Liver fibrosis is a disease that causes high morbidity and has become a major health problem. Liver fibrosis can lead to the end stage of liver diseases (livercirrhosisand hepatocellularcarcinoma). Currently, liver transplantation is the only effective treatment...

["Cell Biology","Gastroenterology and Hepatology","Translational Medicine"]
doi:10.7717/peerj.4336
2 citations
250 downloads
1,288 views

Background Salvia officinalis (sage) is a native plant to the Mediterranean region and has been used for a long time in traditional medicine for various diseases. We investigated possible anti-diabetic, anti-inflammatory and anti-obesity effects of sage methanol...

["Diabetes and Endocrinology","Nutrition","Translational Medicine"]
doi:10.7717/peerj.4166
188 downloads
754 views

Background and Purpose Oxidative stress is involved in normal and pathological functioning of skeletal muscle. Protection of myoblasts from oxidative stress may improve muscle contraction and delay aging. Here we studied the effect of R. coriaria sumac fruit extract...

["Cell Biology","Translational Medicine"]
doi:10.7717/peerj.4144
122 downloads
764 views

Objective Our previous genome-wide association study (GWAS) identified that the ABO rs633862 variant in chromosome 9q34.2 was associated with the risk of epithelial ovarian cancer (EOC) in Chinese Han women. The aim of the present study was to evaluate its prognostic...

["Oncology","Translational Medicine","Women's Health"]
doi:10.7717/peerj.3946
174 downloads
810 views

Bone marrow stimulation may be applied to regenerate focal cartilage defects, but generally results in transient clinical improvement and formation of fibrocartilage rather than hyaline cartilage. Tissue engineering and regenerative medicine strive to develop new...

["Bioengineering","Evidence Based Medicine","Orthopedics","Rheumatology","Translational Medicine"]
doi:10.7717/peerj.3927

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