Peer-reviewed Articles - Medicine

30 downloads
124 views

Background Cyclin A overexpression is found in a variety of human tumors and correlates with unfavorable outcome. We analyzed immunohistochemical expression of cyclin A in Wilms tumor (WT) in relation to clinicopathological characteristics, preoperative chemotherapy...

["Nephrology","Oncology","Pathology","Pediatrics","Urology"]
doi:10.7717/peerj.6212
27 downloads
136 views

Background Autism spectrum disorder (ASD) is a complex heterogeneous developmental disease with a significant genetic background that is frequently caused by rare copy number variants (CNVs). Microarray-based whole-genome approaches for CNV detection are widely...

["Pediatrics","Translational Medicine","Medical Genetics"]
doi:10.7717/peerj.6183
69 downloads
368 views

The study of the burden that parasites can exert upon the bacterial gut microbiota was restricted by the available technologies and their costs. Currently, next-generation sequencing coupled with traditional methodologies allows the study of eukaryotic parasites...

["Bioinformatics","Microbiology","Parasitology","Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.6200
73 downloads
159 views

Background Previous studies have shown that the adaptive immunity function of T cells in disease states correlates with CD3 surface expression closely. During routine assessment of TBNK subsets in peripheral blood of pediatric patients by flow cytometry, we noticed...

["Immunology","Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.6114
39 downloads
239 views

Background Maternal obesity and physical inactivity have been identified as correlates of overweight and obesity and physical inactivity in older preadolescents; however, no study has explored this relationship in Hispanic preadolescents. Furthermore, the relation...

["Epidemiology","Pediatrics","Public Health"]
doi:10.7717/peerj.6100
45 downloads
286 views

Introduction Extant studies have examined the effect of psychological characteristics on clinical features that define behavior problems. The purpose of this study was to analyze the effects of temperament and character as both individual factors and complex profiles...

["Pediatrics","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.6106
54 downloads
288 views

Background Anorectal malformations (ARMs) are the most common congenital malformation of the gut, and regulated by multiple signal transduction pathways. The microRNA (miRNA) expression profiles and their biologial functions in anorectal malformations (ARMs) remain...

["Bioinformatics","Gastroenterology and Hepatology","Pediatrics"]
doi:10.7717/peerj.5774
73 downloads
310 views

Objective Burn wounds are a global public health problem, and a large number of casualties are caused by burns each year. In this study, we explored the epidemiological characteristics associated with burns and the factors affecting the length of hospital stay...

["Epidemiology","Pediatrics","Public Health"]
doi:10.7717/peerj.5740
87 downloads
322 views

Purpose Most studies on neuroblastoma (NB) have been conducted in Western countries or Japan. The objective of our study was to analyze clinical and pathological features, MYCN status, surgical methods, and prognosis in Chinese NB patients. Methods A retrospective,...

["Oncology","Pediatrics","Surgery and Surgical Specialties"]
doi:10.7717/peerj.5665
78 downloads
349 views

Background Sepsis remains a major problem in intensive care medicine. It is often accompanied by coagulopathies, leading to thrombotic occlusion of small vessels with subsequent organ damage and even fatal multi-organ failure. Prediction of the clinical course...

["Emergency and Critical Care","Pediatrics"]
doi:10.7717/peerj.5538
99 downloads
465 views

Objective To systematically review the evidence around the effect of ambient levels of particulate and gaseous pollutants, and the risk of hospitalisation with bronchiolitis for infants under two years of age. Design Systematic review of observational epidemiological...

["Global Health","Pediatrics","Respiratory Medicine"]
doi:10.7717/peerj.5352
112 downloads
421 views

Background Regardless of the advancement in medical technologies, the diagnosis of tuberculosis (TB) in children has remained a challenge. Childhood TB is rampant and an important cause of morbidity and mortality. The objective of this study was to determine the...

["Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.5253
96 downloads
260 views

Background Autotaxin (ATX) is a secreted glycoprotein that is involved in the development of hepatic fibrogenesis via the enzymatic production of lysophosphatidic acid. The aim of this study was to investigate hepatic expression of ATX in biliary atresia (BA) compared...

["Gastroenterology and Hepatology","Pediatrics"]
doi:10.7717/peerj.5224
154 downloads
811 views

The aims of this study were to describe the session rating of perceived exertion (sRPE), total quality recovery (TQR), and variations in countermovement jump (CMJ) height throughout nine weeks of a competitive period in young female basketball players. In total,...

["Kinesiology","Pediatrics"]
doi:10.7717/peerj.5225
91 downloads
476 views

Background The norms for evaluating the maximum expiratory flow (MEF) usually are developed according to chronological age and height. However, to date, little research has been conducted using reference values that take into account the temporal changes of biological...

["Epidemiology","Global Health","Pediatrics","Public Health","Respiratory Medicine"]
doi:10.7717/peerj.5157

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