Peer-reviewed Articles - Medicine

23 downloads
125 views

Background Alu is one of the non-autonomous element retrotransposons, constituting nearly 11% of the human DNA. Methylation changes of the Alu element can cause genomic instability, a hallmark of cancer development, ultimately leading to the development of cancer....

["Biochemistry","Anatomy and Physiology","Orthopedics"]
doi:10.7717/peerj.5492
34 downloads
270 views

Background The objective of this study was to evaluate the changes of the median nerve cross-sectional area (MNCSA) and diameters of the median nerve at different finger postures and wrist angles. Methods Twenty-five healthy male participants were recruited in...

["Kinesiology","Orthopedics"]
doi:10.7717/peerj.5406
39 downloads
170 views

Background Lumbar spinal stenosis (LSS) is a common cause of low back pain with degenerative spinal change in older adults. Telomeres are repetitive nucleoprotein DNA sequences of TTAGGG at the ends of chromosomes. Oxidative stress originates from an imbalance...

["Biochemistry","Geriatrics","Orthopedics"]
doi:10.7717/peerj.5381
38 downloads
174 views

Background The aim of this study was to compare muscle activation onset times of knee muscles between the involved and uninvolved knee of patients with unilateral anterior cruciate ligament reconstruction (ACLR), and the uninjured knees of healthy subjects after...

["Kinesiology","Orthopedics"]
doi:10.7717/peerj.5310
101 downloads
994 views

Background The percentage of sustained maximal oxygen uptake and the running economy are important factors that determine the running success of endurance athletes. Running economy is defined as the oxygen uptake required to run at a given speed and depends on...

["Kinesiology","Orthopedics"]
doi:10.7717/peerj.5219
649 downloads
7,531 views

Background Experimental and clinical evidence support a link between body representations and pain. This proof-of-concept study in people with painful knee osteoarthritis (OA) aimed to determine if: (i) visuotactile illusions that manipulate perceived knee size...

["Neuroscience","Anesthesiology and Pain Management","Orthopedics","Psychiatry and Psychology","Rheumatology"]
doi:10.7717/peerj.5206
95 downloads
477 views

Background Electrical stimulation (ES) has a long history of successful use in the clinical treatment of refractory, non-healing bone fractures and has recently been proposed as an adjunct to bone tissue-engineering treatments to optimize their therapeutic potential....

["Cell Biology","Molecular Biology","Orthopedics"]
doi:10.7717/peerj.4959
139 downloads
453 views

Objectives To evaluate the outcomes of patients with rheumatoid arthritis (RA) of the knee who underwent five portal arthroscopic synovectomy, with or without post-operative negative pressure drainage (NPD). Material and Methods A prospective clinical trial was...

["Clinical Trials","Immunology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.4727
86 downloads
502 views

Objectives Osteoarthritis (OA) and vitamin D deficiency are common health conditions in older people. Whether vitamin D concentration is associated with knee OA is controversial. In this study, we aimed to determine the association between serum concentrations...

["Anesthesiology and Pain Management","Orthopedics","Metabolic Sciences"]
doi:10.7717/peerj.4670
135 downloads
788 views

Background Mechanistic understanding of tendon molecular and cellular biology is crucial toward furthering our abilities to design new therapies for tendon and ligament injuries and disease. Recent transcriptomic and epigenomic studies in the field have harnessed...

["Molecular Biology","Orthopedics"]
doi:10.7717/peerj.4664
102 downloads
793 views

Identifying the separate parts in ultrasound images such as bone and skin plays a crucial role in the synovitis detection task. This paper presents a detector of bone and skin regions in the form of a classifier which is trained on a set of annotated images. Selected...

["Orthopedics","Radiology and Medical Imaging","Rheumatology","Human\u2013Computer Interaction","Computational Science"]
doi:10.7717/peerj.4411
202 downloads
855 views

Long-distance running competitions impose a large amount of mechanical loading and strain leading to muscle edema and delayed onset muscle soreness (DOMS). Damage to various muscle fibers, metabolic impairments and fatigue have been linked to explain how DOMS impairs...

["Kinesiology","Orthopedics","Radiology and Medical Imaging"]
doi:10.7717/peerj.4469
1 citation
309 downloads
1,110 views

Background Several water-based sports (swimming, surfing and stand up paddle boarding) require adequate thoracic mobility (specifically rotation) in order to perform the appropriate activity requirements. The measurement of thoracic spine rotation is problematic...

["Kinesiology","Orthopedics","Science and Medical Education","Human\u2013Computer Interaction"]
doi:10.7717/peerj.4431
139 downloads
779 views

Background Patellofemoral pain (PFP) is often reported as a diffuse pain at the front of the knee during knee-loading activities. A patient’s description of pain location and distribution is commonly drawn on paper by clinicians, which is difficult to quantify,...

["Anesthesiology and Pain Management","Anatomy and Physiology","Orthopedics","Translational Medicine","Human\u2013Computer Interaction"]
doi:10.7717/peerj.4406
626 downloads
8,566 views

Background Impaired patient-reported shoulder function and pain, external-rotation strength, abduction strength, and abduction range-of-motion (ROM) is reported in patients with subacromial impingement (SIS). However, it is unknown how much strength and ROM improves...

["Evidence Based Medicine","Kinesiology","Orthopedics","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4400

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