Peer-reviewed Articles - Medicine

72 downloads
256 views

Diabetic retinopathy (DR) is the most common chronic complication of diabetes. It can cause impaired vision and even blindness. However, the pathological mechanism of DR is still unknown. In the present study, we use bioinformatic analysis to reveal the pathological...

["Bioinformatics","Ophthalmology"]
doi:10.7717/peerj.4762
138 downloads
496 views

Background Polyhexamethylene biguanide (PHMB) eye drops are a frequently used medication to treat Acanthamoeba keratitis. In the absence of marketed PHMB eye drops, pharmacy-compounding units are needed to prepare this much needed treatment, but the lack of validated...

["Drugs and Devices","Ophthalmology"]
doi:10.7717/peerj.4549
88 downloads
734 views

Objective In the foveola of the eye, photoreceptors and Müller cells with a unique morphology have been described, but little is known about their 3D structure and orientation. Considering that there is an angle-dependent change in the foveolar photoreceptor response...

["Biophysics","Cell Biology","Anatomy and Physiology","Ophthalmology","Histology"]
doi:10.7717/peerj.4482
106 downloads
538 views

Based on the existing research on sound symbolism and crossmodal correspondence, this study proposed an extended research on cross-modal correspondence between various sound attributes and color properties in a group of non-synesthetes. In Experiment 1, we assessed...

["Ophthalmology","Psychiatry and Psychology","Statistics"]
doi:10.7717/peerj.4443
134 downloads
719 views

Objective Although research on muscle dysmorphia (MD), a body dysmorphic disorder subtype, has recently increased, the causes and mechanisms underlying this disorder remain unclear. Results from studies examining disorders associated with body image suggest the...

["Kinesiology","Ophthalmology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.4273
1 citation
454 downloads
1,741 views

Recent studies have implicated exotropia as a risk factor for schizophrenia. We determined whether schizophrenia biomarkers have abnormal levels of expression in extraocular muscles from patients with strabismus and explored whether differences in gene expression...

["Ophthalmology","Psychiatry and Psychology"]
doi:10.7717/peerj.4214
133 downloads
2,660 views

Previous studies have used the zebrafish to investigate the biology of lens crystallin proteins and their roles in development and disease. However, little is known about zebrafish α-crystallin promoter function, how it compares to that of mammals, or whether mammalian...

["Developmental Biology","Molecular Biology","Neuroscience","Ophthalmology"]
doi:10.7717/peerj.4093
2 citations
267 downloads
980 views

The purpose of this study was to investigate the benefits of exercises with different cognitive demands for cognitive functions (Executive and non-Executive) in healthy older adults. A cross-sectional design was adopted. In total, 84 healthy older adults were enrolled...

["Neuroscience","Geriatrics","Neurology","Ophthalmology"]
doi:10.7717/peerj.3943
206 downloads
787 views

Background/Aim Strabismus is a common condition with misalignment between two eyes that may lead to decrease of visual acuity, lack of binocularity, and diplopia. It is caused by heterogeneous environmental and genetic risk factors. Our previous research has identified...

["Genetics","Genomics","Ophthalmology","Medical Genetics"]
doi:10.7717/peerj.3935
82 downloads
368 views

Background In late 2015, cut-off points were published for foveal thickness to diagnose diabetic macular oedema taking into account the presence of intraretinal fluid using optical coherence tomography (OCT) in primary care patients (90 µm in the presence of intraretinal...

["Diabetes and Endocrinology","Epidemiology","Evidence Based Medicine","Ophthalmology","Public Health"]
doi:10.7717/peerj.3922
1 citation
136 downloads
792 views

A new method for automatic optic disc localization and segmentation is presented. The localization procedure combines vascular and brightness information to provide the best estimate of the optic disc center which is the starting point for the segmentation algorithm....

["Computational Science","Human-Computer Interaction","Ophthalmology","Radiology and Medical Imaging"]
doi:10.7717/peerj.3763
3 citations
124 downloads
695 views

Objective The trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might be a viable therapeutic approach. Decellularized TM scaffolds have previously been produced...

["Bioengineering","Biotechnology","Ophthalmology"]
doi:10.7717/peerj.3629
171 downloads
790 views

Background Working memory is critical for various cognitive processes and can be separated into two stages: short-term memory storage and manipulation processing. Although previous studies have demonstrated that increased physical activity (PA) improves working...

["Kinesiology","Ophthalmology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.3430
128 downloads
768 views

Background Opacities of the lens are typical age-related phenomena which have a high influence on photoreception and consequently circadian rhythm. In mouse lemurs, a small bodied non-human primate, a high incidence (more than 50% when >seven years) of cataracts...

["Veterinary Medicine","Ophthalmology"]
doi:10.7717/peerj.3258
146 downloads
704 views

The effect of aging on the process of word encoding for fixated words and words presented to the right of the fixation point during the reading of sentences in Chinese was investigated with two disappearing text experiments. The results of Experiment 1 showed that...

["Cognitive Disorders","Ophthalmology","Psychiatry and Psychology"]
doi:10.7717/peerj.2897

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