Peer-reviewed Articles - Medicine

123 downloads
388 views

Background Acute kidney injury (AKI) is associated with a significant increase in morbidity, mortality, and health care costs. In intensive care units (ICU), AKI is commonly multifactorial and frequently involves diverse factors, such as hypovolemia, sepsis, and...

["Nephrology","Pharmacology","Public Health"]
doi:10.7717/peerj.5405
55 downloads
277 views

Background Minimal change disease (MCD) is a form of idiopathic nephrotic syndrome. Compared to children, adult-onset MCD patients are reported to have delayed responses to glucocorticoid treatment. Several studies of children have suggested detecting urinary CD80...

["Immunology","Nephrology"]
doi:10.7717/peerj.5400
50 downloads
233 views

Background Medicare is one of the world’s largest health insurance programs. It provides health insurance to nearly 44 million beneficiaries whose entitlements are based on age, disability, or end-stage renal disease (ESRD). Data of these ESRD beneficiaries are...

["Epidemiology","Health Policy","Nephrology","Public Health","Statistics"]
doi:10.7717/peerj.5284
58 downloads
253 views

Objective To verify self-reported basic and instrumental activities of daily living (IADL) with a disability and the results of performance-based tests (namely the Taiwan performance-based IADL (TPIADL), the 2-minute step test (2MST), the 30-second chair-stand...

["Geriatrics","Global Health","Internal Medicine","Nephrology"]
doi:10.7717/peerj.5286
56 downloads
262 views

Background The importance of circulating antibodies as biomarkers of kidney disease has recently been recognized. However, no study has systematically described the methodology of sample preparation and storage regarding antibodies as biomarkers of kidney disease....

["Immunology","Internal Medicine","Nephrology"]
doi:10.7717/peerj.5178
96 downloads
485 views

Background The vermiform appendix serves as a “safe house” for maintaining normal gut bacteria and appendectomy may impair the intestinal microbiota. Appendectomy is expected to profoundly alter the immune system and modulate the pathogenic inflammatory immune...

["Microbiology","Diabetes and Endocrinology","Internal Medicine","Nephrology"]
doi:10.7717/peerj.5019
67 downloads
403 views

Introduction Ureteropelvic junction obstruction (UPJO) is a common congenital anomaly leading to varying degrees of hydronephrosis (HN), ranging from no apparent effect on the renal function to atrophy. Evaluation of these children is based on Diuretic Renal Scintigraphy...

["Nephrology","Pediatrics","Radiology and Medical Imaging","Urology"]
doi:10.7717/peerj.4791
141 downloads
636 views

Background Chronic kidney disease (CKD) is characterised by long-term kidney damage and renal function decline. Diabetic CKD is the principal subtype of kidney disease in Malaysia and is associated with oxidative stress which plays an important role in development...

["Diabetes and Endocrinology","Nephrology"]
doi:10.7717/peerj.4421
110 downloads
475 views

Background Renal biopsies performed in diabetic patients are increasing and becoming more complex. Comprehensive data on modern spectrum of biopsy-proven renal disease in Chinese diabetic patients are lacking. Methods In a nationwide renal biopsy survey including...

["Diabetes and Endocrinology","Epidemiology","Nephrology","Pathology"]
doi:10.7717/peerj.4522
1 citation
123 downloads
588 views

Background Minimal change disease (MCD) is a kind of nephrotic syndrome (NS). In this study, we aimed to establish a mathematical diagnostic model based on biological parameters to classify MCD. Methods A total of 798 NS patients were divided into MCD group and...

["Bioinformatics","Epidemiology","Nephrology"]
doi:10.7717/peerj.4237
176 downloads
555 views

Background Osteoprotegerin (OPG) is a potential biomarker for severity and complications of cardiovascular diseases. Peripheral arterial disease (PAD) is associated with an increased risk of death in kidney transplantation (KT) patients. This prospective cross-sectional...

["Nephrology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3847
1 citation
87 downloads
698 views

Background Frailty exhibits a high prevalence in end-stage renal disease (ESRD) patients and is associated with adverse health-related outcomes, including falls and fractures. Available studies do not address whether frailty is associated with temporal changes...

["Geriatrics","Nephrology","Palliative Care"]
doi:10.7717/peerj.3542
173 downloads
1,063 views

Background Renal supportive care (RSC) is an important option for elderly individuals reaching end-stage renal disease; however, the frequency of RSC practice is very low among Asian countries. We evaluated the attitude, the knowledge, and the preference for specific...

["Geriatrics","Nephrology","Public Health","Palliative Care"]
doi:10.7717/peerj.3540
2 citations
233 downloads
805 views

Objective To compare the risk of postoperative ureteral stricture formation following retroperitoneal laparoscopic ureterolithotomy (RPLU) and ureteroscopy with holmium: YAG laser lithotripsy (URSL) in patients with proximal ureteral stones. Materials and Methods...

["Nephrology","Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.3483
3 citations
499 downloads
1,619 views

Aim To evaluate the effects of sodium-glucose co-transporter 2 (SGLT2) inhibition on renal function and albuminuria in patients with type 2 diabetes. Methods We conducted systematic searches of PubMed, Embase and Cochrane Central Register of Controlled Trials up...

["Diabetes and Endocrinology","Evidence Based Medicine","Nephrology"]
doi:10.7717/peerj.3405

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