Peer-reviewed Articles - Medicine

32 downloads
198 views

Socioeconomic status is a known determinant of health. In secondary data analyses, we assessed whether socioeconomic status affected health-related quality of life in a group of overweight (body mass index 25–30 kg/m2) middle-aged (45.9 ± 5.4 years) men, recruited...

["Public Health","Metabolic Sciences"]
doi:10.7717/peerj.5193
84 downloads
358 views

Background Obesity-induced glucose metabolism disorder is associated with chronic, low-grade, systemic inflammation and is considered a risk factor for diabetes and metabolic syndrome. Resveratrol (RES), a natural anti-inflammatory compound, is observed to improve...

["Diabetes and Endocrinology","Immunology","Nutrition","Metabolic Sciences"]
doi:10.7717/peerj.5173
41 downloads
309 views

Objective This study was undertaken to detect if free fatty acids (FFA) induce hepatocyte senescence in L-02 cells and if huperzine A has an anti-aging effect in fatty liver cells. Methods L-02 cells were treated with a FFA mixture (oleate/palmitate, at 3:0, 2:1,...

["Gastroenterology and Hepatology","Pharmacology","Medical Genetics","Metabolic Sciences"]
doi:10.7717/peerj.5145
82 downloads
464 views

Every cell in an individual has largely the same genomic sequence and yet cells in different tissues can present widely different phenotypes. This variation arises because each cell expresses a specific subset of genomic instructions. Control over which instructions,...

["Biochemistry","Genetics","Molecular Biology","Metabolic Sciences"]
doi:10.7717/peerj.5062
1 citation
56 downloads
310 views

Background Fetuin-A and leukocyte cell-derived chemotaxin-2 (LECT-2) are liver-derived proteins. Fetuin-A is an independent risk factor for type 2 diabetes (T2D) and obese patients with T2D have higher plasma fetuin-A levels than those without T2D. LECT-2 has positive...

["Gastroenterology and Hepatology","Nutrition","Surgery and Surgical Specialties","Metabolic Sciences"]
doi:10.7717/peerj.4884
76 downloads
459 views

Objectives Osteoarthritis (OA) and vitamin D deficiency are common health conditions in older people. Whether vitamin D concentration is associated with knee OA is controversial. In this study, we aimed to determine the association between serum concentrations...

["Anesthesiology and Pain Management","Orthopedics","Metabolic Sciences"]
doi:10.7717/peerj.4670
176 downloads
750 views

Background Cardiovascular disease is a major cause of mortality and morbidity in people with type 2 diabetes mellitus (T2DM). Studies have consistently identified dyslipidemia as an important risk factor for the development of macrovascular disease. The landmark...

["Diabetes and Endocrinology","Metabolic Sciences"]
doi:10.7717/peerj.4578
103 downloads
590 views

Background Hypoglycemia occurs in an appreciable number of individuals with type 2 diabetes mellitus (T2DM) who are receiving glycemic therapy. Iatrogenic hypoglycemia induces not only complications but also a substantial medical expense. Intervention for relevant...

["Diabetes and Endocrinology","Metabolic Sciences"]
doi:10.7717/peerj.4348
152 downloads
687 views

Objective To investigate the risk factors for osteoporosis in male Taiwanese patients with chronic obstructive pulmonary disease (COPD). Methods This cross-sectional study evaluated male COPD outpatients and age-matched male subjects at a regional teaching hospital....

["Geriatrics","Internal Medicine","Nutrition","Respiratory Medicine","Metabolic Sciences"]
doi:10.7717/peerj.4232
128 downloads
621 views

Background Prader-Willi syndrome (PWS) is a complex, multisystem genetic disorder characterized by a variety of physical, cognitive, and behavioral impairments. PWS is a unique sarcopenia model characterized by an abnormal increase in body fat mass and a decrease...

["Diabetes and Endocrinology","Pediatrics","Medical Genetics","Metabolic Sciences"]
doi:10.7717/peerj.4097
1 citation
126 downloads
622 views

Muscle mass loss and wasting are characteristic features of patients with chronic conditions including cancer. Therapeutic options are still scarce. We hypothesized that cachexia-induced muscle oxidative stress may be attenuated in response to treatment with beta2-adrenoceptor-selective...

["Respiratory Medicine","Metabolic Sciences"]
doi:10.7717/peerj.4109
1 citation
246 downloads
788 views

Background Food selection and ingestion both in humans and rodents, often is a critical factor in determining excess energy intake and its related disorders. Methods Two different concepts of high-fat diets were tested for their obesogenic effects in rats; in both...

["Biochemistry","Nutrition","Metabolic Sciences"]
doi:10.7717/peerj.3697
239 downloads
1,014 views

Background Obesity, a common metabolic disease, is a known cause of male infertility due to its associated health risk. Long noncoding RNAs (lncRNAs) have also been reported to be associated with male reproductive diseases; however, their role in the association...

["Developmental Biology","Molecular Biology","Metabolic Sciences"]
doi:10.7717/peerj.3518
3 citations
157 downloads
842 views

Background Little is known about the role of dietary intake in obstructive sleep apnea (OSA), which could prove important in improving clinical outcomes for people with obesity and/or cardiovascular disease within these populations. Reduction in energy intake typically...

["Epidemiology","Evidence Based Medicine","Nutrition","Respiratory Medicine","Metabolic Sciences"]
doi:10.7717/peerj.3259
2 citations
243 downloads
955 views

Background Synthesis of thyroid hormones and regulation of their metabolism involve free radicals that may affect redox balance in the body. Thyroid disorders causing variations in the levels of thyroid hormones may alter cellular oxidative stress. The aim of this...

["Biochemistry","Molecular Biology","Oncology","Medical Genetics","Metabolic Sciences"]
doi:10.7717/peerj.3365

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