Peer-reviewed Articles - Medicine

39 downloads
234 views

Background The vermiform appendix serves as a “safe house” for maintaining normal gut bacteria and appendectomy may impair the intestinal microbiota. Appendectomy is expected to profoundly alter the immune system and modulate the pathogenic inflammatory immune...

["Microbiology","Diabetes and Endocrinology","Internal Medicine","Nephrology"]
doi:10.7717/peerj.5019
84 downloads
384 views

Mitochondria are small, energy-producing structures vital to the energy needs of the body. Genetic mutations cause mitochondria to fail to produce the energy needed by cells and organs which can cause severe disease and death. These genetic mutations are likely...

["Genetics","Internal Medicine","Neurology","Medical Genetics"]
doi:10.7717/peerj.4790
58 downloads
939 views

Background Epidemiologic data supporting the epilepsy–asthma association are insufficient. Therefore, we examined this association in this study. Methods By using claims data from the National Health Insurance Research Database (Taiwan), we executed a retrospective...

["Epidemiology","Immunology","Internal Medicine","Neurology"]
doi:10.7717/peerj.4792
118 downloads
598 views

This study assessed in detail the influence of four different human proteins on the activation of CD4+ and CD8+ T lymphocytes and on the formation of regulatory T cells. Human whole-blood samples were incubated with four different human proteins. The effects of...

["Allergy and Clinical Immunology","Immunology","Internal Medicine","Pathology","Pediatrics"]
doi:10.7717/peerj.4462
140 downloads
774 views

Background Although several studies have identified risk factors for high blood pressure (BP), data from Afro-Caribbean populations are limited. Additionally, less is known about how putative risk factors operate in young adults and how social factors influence...

["Cardiology","Epidemiology","Global Health","Internal Medicine","Public Health"]
doi:10.7717/peerj.4385
170 downloads
1,160 views

Introduction The treatment with tyrosine kinase inhibitors (TKIs) has drastically improved the outcome of chronic myeloid leukemia (CML) patients. This study was conducted to examine the risk of secondary cancers (SCs) in the CML patients who were diagnosed and...

["Epidemiology","Internal Medicine","Oncology"]
doi:10.7717/peerj.4342
215 downloads
1,094 views

Aim To perform a systematic review and meta-analysis of the weekend effect on the mortality of patients with upper gastrointestinal bleeding(UGIB). Methods The review protocol has been registered in the PROSPERO International Prospective Register of Systematic...

["Emergency and Critical Care","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.4248
141 downloads
603 views

Objective To investigate the risk factors for osteoporosis in male Taiwanese patients with chronic obstructive pulmonary disease (COPD). Methods This cross-sectional study evaluated male COPD outpatients and age-matched male subjects at a regional teaching hospital....

["Geriatrics","Internal Medicine","Nutrition","Respiratory Medicine","Metabolic Sciences"]
doi:10.7717/peerj.4232
154 downloads
464 views

Background Pretreatment platelet count has been reported as a potential tool to predict survival outcome in several solid tumors. However, the predictive value of pretreatment platelet count remains obscure in de novo acute myeloid leukemia (AML) excluding acute...

["Hematology","Internal Medicine","Oncology"]
doi:10.7717/peerj.4139
1 citation
410 downloads
1,115 views

Background Few studies compared the diagnostic value of procalcitonin with a combination of other tests including lactate and high-sensitivity C-reactive protein in the prediction of pathogenic bacteremia in emergency department adult patients. Methods We performed...

["Emergency and Critical Care","Infectious Diseases","Internal Medicine","Pathology"]
doi:10.7717/peerj.4094
157 downloads
556 views

Background Astragalus polysaccharide (APS) has immunomodulatory activities on porcine peripheral blood mononuclear cells. The immunomodulatory effects of APS on porcine endothelial cells (ECs) expose to classical swine fever virus (CSFV) remain unknown. Methods...

["Cell Biology","Veterinary Medicine","Infectious Diseases","Internal Medicine"]
doi:10.7717/peerj.3862
3 citations
276 downloads
1,267 views

Aim To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. Methods The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical...

["Clinical Trials","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.3654
2 citations
183 downloads
982 views

Oxidative damage is a major cause of lung diseases, including pulmonary fibrosis. Laminarin is a kind of polysaccharide extracted from brown algae and plays vital roles in various biological processes. However, the functions and mechanisms of laminarin in pulmonary...

["Molecular Biology","Clinical Trials","Internal Medicine","Otorhinolaryngology"]
doi:10.7717/peerj.3642
166 downloads
772 views

Objective The purpose of this study was to assess the effects of age, body condition score (BCS) and muscle condition score (MCS) on indirect radial and coccygeal Doppler systolic arterial blood pressure (SAP) measurements in dogs. Methods Sixty-two privately-owned...

["Veterinary Medicine","Internal Medicine"]
doi:10.7717/peerj.3101
242 downloads
682 views

Background This study evaluates two procedures for typing of Streptococcus agalactiae (group B streptococci; GBS) isolates, using retrospective typing data from the period 2010 to 2014 with a commercial latex agglutination test (latex test) and the Lancefield precipitation...

["Microbiology","Epidemiology","Infectious Diseases","Internal Medicine","Pediatrics"]
doi:10.7717/peerj.3105

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