Peer-reviewed Articles - Medicine

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Background Dengue fever has rapidly manifested into a serious global health concern. The emergence of various viral serotypes has prompted the urgent need for innovative drug design techniques. Of the viral non-structural enzymes, the NS5 RNA-dependent RNA polymerase...

["Bioinformatics","Computational Biology","Genomics","Infectious Diseases"]
doi:10.7717/peerj.5068
9 downloads
80 views

Microbiota-driven variations in the inflammatory response are predicted to regulate host responses to infection. Increasing evidence indicates that the gastrointestinal and respiratory tracts have an intimate relationship with each other. Gut microbiota can influence...

["Biodiversity","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.5637
49 downloads
596 views

Background The World Health Organization (WHO) declares Chikungunya (CHIK) infection to be endemic in South Asia. Despite its first outbreak in Pakistan, no documented evidence exists which reveals the knowledge or awareness of healthcare students and workers (HCSW)...

["Infectious Diseases","Public Health"]
doi:10.7717/peerj.5481
76 downloads
314 views

Background Extraintestinal pathogenic Escherichia coli (ExPEC) is an important bacterium and responsible for many bloodstream infections, including urinary tract infections and even fatal bacteremia. The aim of this research was to investigate whether ExPEC strains...

["Microbiology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.5470
77 downloads
252 views

Salmonella is one of the major foodborne pathogens worldwide. The antimicrobial resistance (AMR) of this foodborne pathogen has raised a great concern in recent years. Studies on the frequency and characterization of Salmonella serotypes can help to improve our...

["Microbiology","Epidemiology","Global Health","Infectious Diseases","Public Health"]
doi:10.7717/peerj.5482
51 downloads
395 views

The growth of migrant communities continues to rise globally, creating unique and complex health challenges. Literature on immigrant health in New Zealand (NZ) remains scant. This integrative literature review was conducted drawing on peer-reviewed research articles...

["Global Health","Health Policy","Infectious Diseases","Public Health"]
doi:10.7717/peerj.5184
87 downloads
498 views

Background It is possible to detect bacterial species in shotgun metagenome datasets through the presence of only a few sequence reads. However, false positive results can arise, as was the case in the initial findings of a recent New York City subway metagenome...

["Bioinformatics","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.5515
93 downloads
370 views

Background Nontuberculous mycobacterial (NTM) infection is increasing worldwide. Current epidemiological data and knowledge of risk factors for this disease are limited. We investigated the trends in and risk of NTM infection in Northeast Thailand during 2012–2016....

["Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.5479
65 downloads
237 views

Purpose This study aims to assess the microbiological profile, antimicrobial susceptibility and adequacy of intravenous ceftriaxone and metronidazole as empirical therapy for surgical patients presenting with complicated intra-abdominal infection. Methods This...

["Epidemiology","Infectious Diseases","Surgery and Surgical Specialties"]
doi:10.7717/peerj.5383
71 downloads
582 views

Background Buruli ulcer is a disease of the skin and soft tissues caused by infection with a slow growing pathogen, Mycobacterium ulcerans. A vaccine for this disease is not available but M. ulcerans possesses a giant plasmid pMUM001 that harbours the polyketide...

["Microbiology","Immunology","Infectious Diseases"]
doi:10.7717/peerj.5294
62 downloads
264 views

Background Regardless of the advancement in medical technologies, the diagnosis of tuberculosis (TB) in children has remained a challenge. Childhood TB is rampant and an important cause of morbidity and mortality. The objective of this study was to determine the...

["Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.5253
69 downloads
375 views

Anthrax caused by Bacillus anthracis is an old and neglected zoonosis that continues to raise concerns in Southern Africa. In this study, twenty (20) slides with suspected isolates of B. anthracis from anthrax cases between 1990 and 2014 and two (2) from that of...

["Veterinary Medicine","Infectious Diseases"]
doi:10.7717/peerj.5270
71 downloads
257 views

Background Candida may form biofilms, which are thought to underlie the most recalcitrant infections. Methods In this study, activities of antifungal agents alone and in combination with tigecycline against planktonic cells and mature and developing biofilms of...

["Microbiology","Mycology","Infectious Diseases"]
doi:10.7717/peerj.5263
108 downloads
340 views

Background Long noncoding RNAs (lncRNAs) are regulatory molecules that participate in biological processes such as stem cell differentiation. Periodontal ligament stem cells (PDLSCs) exhibit great potential for the regeneration of periodontal tissue and the formation...

["Bioinformatics","Dentistry","Infectious Diseases"]
doi:10.7717/peerj.5214
98 downloads
450 views

Objective The study objective is to analyze influenza vaccination status by demographic factors, perceived vaccine efficacy, social influence, herd immunity, vaccine cost, health insurance status, and barriers to influenza vaccination among adults 18 years and...

["Epidemiology","Infectious Diseases","Public Health","Statistics"]
doi:10.7717/peerj.5171

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