Peer-reviewed Articles - Medicine

28 downloads
132 views

Objective The benefits of IL-35 treatment have been verified in multiple animal models of diseases, while its influence on T cells immunity under normal condition still needs to be elucidated. The present study was designed to investigate the effects modulating...

["Immunology","Translational Medicine"]
doi:10.7717/peerj.5638
24 downloads
502 views

Background Silver nanoparticles (AgNPs) have been widely used in many commercial products due to their excellent antibacterial ability. The AgNPs are released into the environment, gradually accumulate in the ocean, and may affect animals at high trophic levels,...

["Toxicology","Veterinary Medicine","Immunology","Ecotoxicology","Environmental Contamination and Remediation"]
doi:10.7717/peerj.5432
55 downloads
277 views

Background Minimal change disease (MCD) is a form of idiopathic nephrotic syndrome. Compared to children, adult-onset MCD patients are reported to have delayed responses to glucocorticoid treatment. Several studies of children have suggested detecting urinary CD80...

["Immunology","Nephrology"]
doi:10.7717/peerj.5400
51 downloads
300 views

Background Pemphigus is a common life-threatening, autoimmune bullous disease effecting both cutaneous and mucous membranes. Previous diagnosis of pemphigus is based on clinical presentations, histopathology, immunofluorescence and enzyme-linked immunosorbent assay....

["Allergy and Clinical Immunology","Dermatology","Immunology"]
doi:10.7717/peerj.5388
78 downloads
290 views

Disease relapse occurs in unrelated cord blood transplantation (CBT) even when the alleles of human leukocyte antigen (HLA) are fully matched between donor and recipient. This is similar to that observed in other types of hematopoietic stem cell transplantation....

["Immunology"]
doi:10.7717/peerj.5228
71 downloads
582 views

Background Buruli ulcer is a disease of the skin and soft tissues caused by infection with a slow growing pathogen, Mycobacterium ulcerans. A vaccine for this disease is not available but M. ulcerans possesses a giant plasmid pMUM001 that harbours the polyketide...

["Microbiology","Immunology","Infectious Diseases"]
doi:10.7717/peerj.5294
109 downloads
434 views

Background Somatic point substitution mutations in the KRAS proto-oncogene primarily affect codons 12/13 where glycine is converted into other amino acids, and are highly prevalent in pancreatic, colorectal, and non-small cell lung cancers. These cohorts are non-responsive...

["Bioinformatics","Immunology","Oncology"]
doi:10.7717/peerj.5056
56 downloads
262 views

Background The importance of circulating antibodies as biomarkers of kidney disease has recently been recognized. However, no study has systematically described the methodology of sample preparation and storage regarding antibodies as biomarkers of kidney disease....

["Immunology","Internal Medicine","Nephrology"]
doi:10.7717/peerj.5178
85 downloads
454 views

HLA class II proteins are important elements of human adaptive immune recognition and are associated with numerous infectious and immune-mediated diseases. These highly variable molecules can be classified into DP, DQ and DR groups. It has been proposed that in...

["Computational Biology","Immunology"]
doi:10.7717/peerj.5118
89 downloads
499 views

Ovine footrot is a degenerative disease of sheep feet leading to the separation of hoof-horn from the underlying skin and lameness. This study quantitatively examined histological features of the ovine interdigital skin as well as their relationship with pro-inflammatory...

["Agricultural Science","Veterinary Medicine","Immunology","Histology"]
doi:10.7717/peerj.5097
178 downloads
603 views

Background Obesity-induced glucose metabolism disorder is associated with chronic, low-grade, systemic inflammation and is considered a risk factor for diabetes and metabolic syndrome. Resveratrol (RES), a natural anti-inflammatory compound, is observed to improve...

["Diabetes and Endocrinology","Immunology","Nutrition","Metabolic Sciences"]
doi:10.7717/peerj.5173
67 downloads
444 views

Many reports have mentioned the association between chronic periodontitis (CP) and primary Sjögren syndrome (pSS). However, no cohort study has been performed for the risk of pSS in patients with CP. In this study, we evaluated the risk of pSS from CP exposure...

["Dentistry","Epidemiology","Immunology","Public Health","Rheumatology"]
doi:10.7717/peerj.5109
106 downloads
424 views

Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals that has caused tremendous economic losses worldwide. In this study, we designed a chimeric nanoparticles (CNPs) vaccine that displays the predominant epitope of the serotype O...

["Bioengineering","Biotechnology","Immunology"]
doi:10.7717/peerj.4823
95 downloads
1,261 views

Background Epidemiologic data supporting the epilepsy–asthma association are insufficient. Therefore, we examined this association in this study. Methods By using claims data from the National Health Insurance Research Database (Taiwan), we executed a retrospective...

["Epidemiology","Immunology","Internal Medicine","Neurology"]
doi:10.7717/peerj.4792
99 downloads
717 views

Background Periodontitis is associated with increased concentration of inflammatory markers and saliva has been proposed as a non-invasive diagnostic fluid in oral and systemic diseases. The levels of salivary biomarkers, such as cytokines, could potentially be...

["Dentistry","Epidemiology","Immunology","Nursing"]
doi:10.7717/peerj.4710

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