Peer-reviewed Articles - Medicine

44 downloads
235 views

Background Regular exercise training stimulates physiological adaptations to improve physical performance, reduce chronic disease risk, and slow age-related cognitive decline. Since the physiological mechanisms responsible for aging-associated cognitive decline...

["Geriatrics","Kinesiology"]
doi:10.7717/peerj.6159
135 downloads
549 views

Background The ability to jump has been related to muscle strength and power, speed and amplitude of the lower limbs movements, and specifically for the elderly, the vertical jump has been shown to be a good predictor of functional capacity and risk of falling....

["Geriatrics","Kinesiology"]
doi:10.7717/peerj.5804
124 downloads
654 views

Background Benzodiazepines (BZDs) and z-drugs are effective drugs, but they are prescribed excessively worldwide. International guidelines recommend a maximum treatment duration of 4 weeks. Although these drugs are effective in the short-term, long-term BZD therapy...

["Geriatrics","Pharmacology"]
doi:10.7717/peerj.5535
96 downloads
417 views

Background The current study aimed to reconcile the inconsistent findings between obesity, executive functions, and episodic memory by addressing major limitations of previous studies, including overreliance on body mass index (BMI), small sample sizes, and failure...

["Geriatrics","Psychiatry and Psychology"]
doi:10.7717/peerj.5624
137 downloads
674 views

Introduction Assessment of episodic memory is traditionally used to evaluate potential cognitive impairments in senior adults. The present article discusses the capabilities of Episodix, a game to assess the aforementioned cognitive area, as a valid tool to discriminate...

["Bioengineering","Bioinformatics","Cognitive Disorders","Geriatrics","Neurology"]
doi:10.7717/peerj.5478
171 downloads
688 views

Sarcopenia is an age-related disease characterized by the loss of muscle mass and muscle function. A proper understanding of its pathogenesis and mechanisms may lead to new strategies for diagnosis and treatment of the disease. This study aims to discover the underlying...

["Bioinformatics","Diabetes and Endocrinology","Geriatrics","Medical Genetics"]
doi:10.7717/peerj.5239
97 downloads
364 views

Background Quality of life is an important health outcome for older persons. It predicts the adverse outcomes of institutionalization and premature death. The aim of this cross-sectional study was to determine the influence of both disability in activities of daily...

["Geriatrics","Public Health"]
doi:10.7717/peerj.5425
88 downloads
339 views

Background Lumbar spinal stenosis (LSS) is a common cause of low back pain with degenerative spinal change in older adults. Telomeres are repetitive nucleoprotein DNA sequences of TTAGGG at the ends of chromosomes. Oxidative stress originates from an imbalance...

["Biochemistry","Geriatrics","Orthopedics"]
doi:10.7717/peerj.5381
96 downloads
350 views

Objective To verify self-reported basic and instrumental activities of daily living (IADL) with a disability and the results of performance-based tests (namely the Taiwan performance-based IADL (TPIADL), the 2-minute step test (2MST), the 30-second chair-stand...

["Geriatrics","Global Health","Internal Medicine","Nephrology"]
doi:10.7717/peerj.5286
198 downloads
695 views

Background Alzheimer’s disease (AD) is a neurodegenerative disease that is characterized by deficits in episodic memory. It is the most common form of dementia and affects 50–70% of patients with cognitive impairments over the age of 65. Elderly people are particularly...

["Cognitive Disorders","Epidemiology","Geriatrics","Nursing","Nutrition"]
doi:10.7717/peerj.5150
104 downloads
323 views

Objective MicroRNA (miR)-122 is highly expressed in the liver, where it has been implicated as a regulator of fatty-acid metabolism. A recent study reported that miR-122 plays a role in pathogenesis of atherosclerosis; however, whether it connects with severity...

["Cardiology","Geriatrics"]
doi:10.7717/peerj.5218
213 downloads
730 views

Introduction The long-term use of benzodiazepines (BZD) and z-drugs in older populations is associated with a variety of sociodemographic and health-related factors. Recent studies reported that long-term BZD and z-drugs use is associated with increased age, female...

["Geriatrics","Pharmacology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.4614
307 downloads
2,421 views

Background The purpose of this study was to analyze the relationships between muscular performance consisting of a single repetition on the chair squat exercise (CSQ) and different measures of functional capacity, balance, quality of life and cognitive status in...

["Geriatrics","Kinesiology","Nursing","Science and Medical Education","Human\u2013Computer Interaction"]
doi:10.7717/peerj.4712
1 citation
204 downloads
748 views

Background Frailty associated with aging increases the risk of falls, disability, and death. We investigated gender-associated factors for frailty. Methods Data of 3,079 geriatric subjects were retrieved from the National Health and Nutrition Examination Survey...

["Geriatrics","Public Health"]
doi:10.7717/peerj.4326
1 citation
278 downloads
1,131 views

Background Force platform training with functional electric stimulation aimed at improving balance may be effective in fall prevention for older adults. Aim of the study is to evaluate the effects of the visual-feedback-based force platform balance training with...

["Clinical Trials","Geriatrics"]
doi:10.7717/peerj.4244

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