Peer-reviewed Articles - Medicine

19 downloads
107 views

Introduction The present study investigated the crucial role of inflammation-based prognostic scores in locally advanced cervical esophageal squamous cell carcinoma (ESCC) patients who underwent curative concurrent chemoradiotherapy (CCRT). Methods There were 411...

["Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5655
30 downloads
132 views

Background Abnormal methylation of TNFRSF10C was found to be associated with different types of cancers, excluding colorectal cancer (CRC). In this paper, the performance of TNFRSF10C methylation in CRC was studied in two stages. Method The discovery stage was...

["Biochemistry","Genetics","Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5336
26 downloads
123 views

Background and Aims To prospectively evaluate the effects of antiviral therapy on liver hemodynamics in patients with hepatitis B cirrhosis. Methods Seventy consecutive eligible HBV-related cirrhotic inpatients were enrolled in the prospective study. Fifty-two...

["Gastroenterology and Hepatology","Radiology and Medical Imaging"]
doi:10.7717/peerj.5484
17 downloads
130 views

Some plants popularly employed for the treatment of peptic ulcers have proved to be attractive sources of new drugs. Despite extensive research, the pharmacological and toxicological potentials of these plants are not fully understood. In this context, the aim...

["Plant Science","Drugs and Devices","Gastroenterology and Hepatology"]
doi:10.7717/peerj.5375
41 downloads
261 views

Background Except for a few studies with contradictory observations, information is lacking on the possibility of association between DNA mismatch repair (MMR) status and the presence of cancer stem cells in colorectal carcinoma (CRC), two important aspects in...

["Gastroenterology and Hepatology","Pathology"]
doi:10.7717/peerj.5530
61 downloads
233 views

Background Intra-abdominal adhesions develop after nearly every abdominal surgery, commonly causing female infertility, chronic pelvic pain, and small bowel obstruction. Pentoxifylline (PTX) is a methylxanthine compound with immunomodulatory and antifibrotic properties....

["Drugs and Devices","Gastroenterology and Hepatology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.5434
79 downloads
307 views

Objective The mechanism underlying colon cancer metastasis remain unclear. This study aimed to elucidate the genes alteration during the metastasis of colon cancer and identify genes that crucial to the metastasis and survival of colon cancer patients. Methods...

["Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5433
153 downloads
623 views

Objectives To comprehensively analyse the global scientific outputs of hepatocellular carcinoma (HCC) research. Methods Data of publications were downloaded from the Web of Science Core Collection. We used CiteSpace IV and Excel 2016 to analyse literature information,...

["Gastroenterology and Hepatology","Oncology","Statistics"]
doi:10.7717/peerj.5477
145 downloads
630 views

The beneficial effects of prebiotic fibres on human health have been related to their capacities to alter the gut microbiota and modify the growth of beneficial microorganisms. It is long appreciated that bacterial metabolites affect the host’s physiology. The...

["Cell Biology","Food Science and Technology","Microbiology","Gastroenterology and Hepatology","Nutrition"]
doi:10.7717/peerj.5288
66 downloads
170 views

Background Autotaxin (ATX) is a secreted glycoprotein that is involved in the development of hepatic fibrogenesis via the enzymatic production of lysophosphatidic acid. The aim of this study was to investigate hepatic expression of ATX in biliary atresia (BA) compared...

["Gastroenterology and Hepatology","Pediatrics"]
doi:10.7717/peerj.5224
117 downloads
1,003 views

Background Antibiotic-associated gastrointestinal signs (AAGS) occur commonly in cats. Co-administration of synbiotics is associated with decreased AAGS in people, potentially due to stabilization of the fecal microbiome and metabolome. The purpose of this double-blinded...

["Microbiology","Veterinary Medicine","Gastroenterology and Hepatology","Internal Medicine","Translational Medicine"]
doi:10.7717/peerj.5130
190 downloads
638 views

Objective Gastric cancer (GC) is the fourth most common cause of cancer-related deaths in the world. In the current study, we aim to identify the hub genes and uncover the molecular mechanisms of GC. Methods The expression profiles of the genes and the miRNAs were...

["Bioinformatics","Gastroenterology and Hepatology","Data Mining and Machine Learning"]
doi:10.7717/peerj.5180
162 downloads
893 views

Background Obesity is a key public health problem. The advancement of gut microbiota research sheds new light on this field. This article aims to present the research trends in global intestinal microbiota studies within the domain of obesity research. Methods...

["Evidence Based Medicine","Gastroenterology and Hepatology","Global Health","Data Mining and Machine Learning","Data Science"]
doi:10.7717/peerj.5091
67 downloads
431 views

Objective This study was undertaken to detect if free fatty acids (FFA) induce hepatocyte senescence in L-02 cells and if huperzine A has an anti-aging effect in fatty liver cells. Methods L-02 cells were treated with a FFA mixture (oleate/palmitate, at 3:0, 2:1,...

["Gastroenterology and Hepatology","Pharmacology","Medical Genetics","Metabolic Sciences"]
doi:10.7717/peerj.5145
80 downloads
361 views

Background Publication bias is the tendency of investigators, reviewers, and editors to submit or accept manuscripts for publication based on their direction or strength of findings. In this study, we investigated if publication bias was present in gastroenterological...

["Epidemiology","Evidence Based Medicine","Gastroenterology and Hepatology"]
doi:10.7717/peerj.4995

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